Abdelrazig, Salah Ortori, Catharine A Doherty, Michael Valdes, Ana M Chapman, Victoria Barrett, David A
Published in
Metabolomics : Official journal of the Metabolomic Society
Osteoarthritis (OA) is a common cause of disability in older people, but its aetiology is not yet fully understood. Biomarkers of OA from metabolomics studies have shown potential use in understanding the progression and pathophysiology of OA. To investigate possible surrogate biomarkers of knee OA in urine using metabolomics to contribute towards ...
Lindgren, Moa Jansson, Malin Tavelin, Björn Dirix, Luc Vermeulen, Peter Nyström, Hanna
Published in
Clinical & experimental metastasis
No reliable, non-invasive biomarker of metastatic breast cancer (mBC) exists: circulating CA15-3 (cCA15-3) is the marker mostly used to monitor mBC. Circulating collagen IV (cCOLIV) has been evaluated in other metastatic cancers and has been found to be a promising biomarker. The overarching aim of this study was to evaluate cCOLIV as a potential b...
Yang, Chongtu Liu, Fen Liu, Wei Cao, Guijuan Liu, Jiacheng Huang, Songjiang Zhu, Muxin Tu, Chao Wang, Jianwen Xiong, Bin
...
Published in
International journal of cardiology
Coronavirus disease 2019 (COVID-19) pneumonia tends to affect cardiovascular system and cause cardiovascular damage. This study aimed to explore the prevalence of myocardial injury and risk factors for mortality in patients with COVID-19 pneumonia. Two hundred and twenty-four consecutive patients with confirmed diagnosis of SARS-CoV-2 infection and...
Kong, Weili Zheng, Yun Xu, Wei Gu, Hailing Wu, Junhao
Published in
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Patients with severe obstructive sleep apnea-hypopnea syndrome are often accompanied by symptoms such as decreased cognitive function and daytime sleepiness, while cognitive function is often associated with biomarkers of Alzheimer's disease. Therefore, this study aims to explore the level of Alzheimer's disease biomarkers in the plasma of obstruct...
Ueberroth, Benjamin E Khan, Adnan Zhang, Kevin J Philip, Philip A
Published in
Journal of gastrointestinal cancer
Pancreatic adenocarcinoma remains a malignancy with poor prognosis. Black patients experience poorer overall survival compared with other races. Recent studies have elucidated certain prognostic factors at the time of diagnosis of pancreatic cancer which have largely not been studied for differences between racial groups. We present a study examini...
Mueller, Christian Giannitsis, Evangelos Jaffe, Allan S Huber, Kurt Mair, Johannes Cullen, Louise Hammarsten, Ola Mills, Nicholas L Möckel, Martin Krychtiuk, Konstantin
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Published in
European heart journal. Acute cardiovascular care
The coronavirus disease 2019 (COVID-19) pandemic has increased awareness that severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2) may have profound effects on the cardiovascular system. COVID-19 often affects patients with pre-existing cardiac disease, and may trigger acute respiratory distress syndrome (ARDS), venous thromboembol...
Zong, Zhen Hu, Ce-Gui Zhou, Tai-Cheng Yu, Zhuo-Min Tang, Fu-Xin Tian, Hua-Kai Li, Hui Wang, He
Published in
World Journal of Gastrointestinal Surgery
BACKGROUND Investigating molecular biomarkers that accurately predict prognosis is of considerable clinical significance. Accumulating evidence suggests that long non-coding ribonucleic acids (lncRNAs) are frequently aberrantly expressed in colorectal cancer (CRC). AIM To elucidate the prognostic function of multiple lncRNAs serving as biomarkers i...
Lyu, Hai-Rong He, Xiao-Yuan Hao, Hong-Jun Lu, Wen-Yi Jin, Xin Zhao, Yu-Jiao Zhao, Ming-Feng
Published in
World Journal of Clinical Cases
BACKGROUND Central nervous system graft- vs -host disease (CNS-GVHD) is a rare cause of CNS disorders after allogeneic hematopoietic stem cell transplantation. Currently, establishing a diagnosis of CNS-GVHD is challenging because the diagnostic criteria and diagnostic methods are not well defined and many confounding factors need to be ruled out. ...
Park, Jong-Ho Lim, Shinn-Won Myung, Woojae Park, Inho Jang, Hyeok-Jae Kim, Seonwoo Lee, Min-Soo Chang, Hun Soo Yum, DongHo Suh, Yeon-Lim
...
Published in
Scientific Reports
Achieving remission following initial antidepressant therapy in patients with major depressive disorder (MDD) is an important clinical result. Making predictions based on genetic markers holds promise for improving the remission rate. However, genetic variants found in previous genetic studies do not provide robust evidence to aid pharmacogenetic d...
Shaffie, Ahmed Soliman, Ahmed Fu, Xiao-An Nantz, Michael Giridharan, Guruprasad van Berkel, Victor Khalifeh, Hadil Abu Ghazal, Mohammed Elmaghraby, Adel El-baz, Ayman
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Published in
Scientific Reports
This study presents a non-invasive, automated, clinical diagnostic system for early diagnosis of lung cancer that integrates imaging data from a single computed tomography scan and breath bio-markers obtained from a single exhaled breath to quickly and accurately classify lung nodules. CT imaging and breath volatile organic compounds data were coll...
