Ho, Rainbow T H Fong, Ted C T Chan, Wai Chi Kwan, Joseph S K Chiu, Patrick K C Yau, Joshua C Y Lam, Linda C W
Published in
The journals of gerontology. Series B, Psychological sciences and social sciences
Dementia interferes with older adults' functioning in cognitive, daily, psychosocial, and neuroendocrine domains. The present study examined the psychophysiological effects of dance movement therapy (DMT) and physical exercise for older adults with dementia. This randomized controlled trial recruited 204 older adults diagnosed with mild dementia in...
Shaheen, Hala Sobhy, Sayed El Mously, Sherine Abuomira, Marwa Mansour, Mohamed
Published in
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
BackgroundParkinson’s disease (PD) is one of the most common degenerative diseases of the central nervous system (CNS). Alpha-synuclein (A-syn) plays a critical role in the pathogenesis of PD. The close relation between the salivary glands and the CNS could render the A-syn secretions in the saliva useful biomarkers for PD.Aim of the workTo study t...
Katulka, Riley Jeremy Al Saadon, Abdalrhman Sebastianski, Meghan Featherstone, Robin Vandermeer, Ben Silver, Samuel A. Gibney, R. T. Noel Bagshaw, Sean M. Rewa, Oleksa G.
Published in
Critical Care
IntroductionRenal replacement therapy (RRT) is associated with high mortality and costs; however, no clinical guidelines currently provide specific recommendations for clinicians on when and how to stop RRT in recovering patients. Our objective was to systematically review the current evidence for clinical and biochemical parameters that can be use...
Lu, Hongsheng Zhang, Lihong Dai, Yuechu Ruan, Yanyun Cao, Xuequan Cai, Xiaobo Ruan, Sihan Chen, Qi
Published in
Diagnostic Pathology
BackgroundPapillary thyroid carcinoma (PTC) is an indolent tumor that is exploding with increasing thyroid nodules (TN). Environmental carcinogens, lifestyle changes increased the incidence of thyroid carcinoma. With the development of B-ultrasound imaging, more and more thyroid cancer has been found. There has been a debate about whether thyroid c...
Fontes-Sousa, Mário Lobo, João Lobo, Silvana Salta, Sofia Amorim, Maria Lopes, Paula Antunes, Luís de Sousa, Susana Palma Henrique, Rui Jerónimo, Carmen
...
Published in
Molecular Medicine
BackgroundBreast cancer (BC) is a major health concern and better understanding of its biology might improve treatment decisions and patient outcomes. Histone3 Lysine27 tri-methylation (H3K27me3) is a post-translational histone modification frequently associated with altered gene expression. In BC patients, lower H3K27me3 expression has been associ...
Burnham, Philip Gomez-Lopez, Nardhy Heyang, Michael Cheng, Alexandre Pellan Lenz, Joan Sesing Dadhania, Darshana M. Lee, John Richard Suthanthiran, Manikkam Romero, Roberto De Vlaminck, Iwijn
...
Published in
Microbiome
BackgroundCell-free DNA (cfDNA) in blood, urine, and other biofluids provides a unique window into human health. A proportion of cfDNA is derived from bacteria and viruses, creating opportunities for the diagnosis of infection via metagenomic sequencing. The total biomass of microbial-derived cfDNA in clinical isolates is low, which makes metagenom...
Begg, Gordon A. Swoboda, Peter P. Karim, Rashed Oesterlein, Tobias Rhode, Kawal Holden, Arun V. Greenwood, John P. Shantsila, Eduard Lip, Gregory Y. H. Plein, Sven
...
Published in
Journal of Cardiovascular Magnetic Resonance
BackgroundUsing cardiovascular magnetic resonance imaging (CMR), it is possible to detect diffuse fibrosis of the left ventricle (LV) in patients with atrial fibrillation (AF), which may be independently associated with recurrence of AF after ablation. By conducting CMR, clinical, electrophysiology and biomarker assessment we planned to investigate...
Zakaria, Rasheed Chen, Yin Jie Hughes, David M. Wang, Sumei Chawla, Sanjeev Poptani, Harish Berghoff, Anna S. Preusser, Matthias Jenkinson, Michael D. Mohan, Suyash
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Published in
Cancer Imaging
BackgroundBrain metastases are common in clinical practice. Many clinical scales exist for predicting survival and hence deciding on best treatment but none are individualised and none use quantitative imaging parameters. A multicenter study was carried out to evaluate the prognostic utility of a simple diffusion weighted MRI parameter, tumor appar...
Zhou, Wenjia Chen, Lu Li, Chao Huang, Rui Guo, Mian Ning, Shangwei Ji, Jingjing Guo, Xiaorong Lou, Ge Jia, Xinqi
...
Published in
Cancer Cell International
Pancreatic cancer (PC) is one of the leading causes of cancer-related deaths worldwide. Due to the shortage of effective biomarkers for predicting survival and diagnosing PC, the underlying mechanism is still intensively investigated but poorly understood. Long noncoding RNAs (lncRNAs) provide biological functional diversity and complexity in prote...
Khatun, Ayesha Paterson, Ross W. Schöll, Michael
Published in
Alzheimer's Research & Therapy
Biomarkers are increasingly employed for effective research into neurodegenerative diseases. They have become essential for reaching an accurate clinical diagnosis, monitoring disease, and refining entry criteria for participation in clinical treatment trials, and will be key in measuring target engagement and treatment outcome in disease-modifying...
