Garro-Aguilar, Yaiza Cayssials, Valerie Achaintre, David Boeing, Heiner Mancini, Francesca Romana Mahamat-Saleh, Yahya Boutron-Ruault, Marie-Christine Kühn, Tilman Katzke, Verena Trichopoulou, Antonia
...
Published in
European journal of nutrition
In this study, we aimed to study the correlation between acute and habitual intakes of flavonols, their main food sources and their 24-h urinary concentrations in an European population. A 24-h dietary recall (24-HDR) and 24-h urine samples were collected on the same day from a convenience subsample of 475 men and women from four countries (France,...
canu, guseva
Oxidative stress reflects a disturbance in the balance between the production and accumulation of reactive oxygen species (ROS). ROS are scavenged by the antioxidant system, but when in excess concentration, they can oxidize proteins, lipids, and DNA. DNA damage is usually repaired, and the oxidized products are excreted in urine. 8-hydroxy-2-deoxy...
Huang, Biao Han, Wei Sheng, Zu-Feng Shen, Guo-Liang
Published in
Cancer Cell International
BackgroundSkin cutaneous melanoma (SKCM) is one of the most malignant and aggressive cancers, causing about 72% of deaths in skin carcinoma. Although extensive study has explored the mechanism of recurrence and metastasis, the tumorigenesis of cutaneous melanoma remains unclear. Exploring the tumorigenesis mechanism may help identify prognostic bio...
Ni, Wen-Juan Leng, Xiao-Min
Published in
Molecular Medicine
BackgroundMicroRNAs (miRNAs) play crucial roles in regulating eukaryotic gene expression. Recent studies indicated that aberrantly expressed miRNAs are involved in the pathogenesis of ankylosing spondylitis (AS). Indeed, hsa-miR-495-3p (miR-495) has been reported as an anti-oncogene in different cancers. However, the role of miR-495 in AS is still ...
Norouzi-Barough, Leyla Asgari Khosro Shahi, Amir Mohebzadeh, Farnoosh Masoumi, Ladan Haddadi, Mohammad Reza Shirian, Sadegh
Published in
Cancer Cell International
Exosomes (EXs) are small extracellular vesicles, a size range of 40-100 nm in diameter, actively secreted by most eukaryotic cells into surrounding body fluids like blood, saliva, urine, bile, breast milk and etc. These endosomal-derived vesicles mediate cell–cell communication between various cell populations through transmitting different signali...
Konan, Henri-Philippe Kassem, Loay Omarjee, Soleilmane Surmieliova-Garnès, Ausra Jacquemetton, Julien Cascales, Elodie Rezza, Amélie Trédan, Olivier Treilleux, Isabelle Poulard, Coralie
...
Published in
Breast Cancer Research
BackgroundAlterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR), respectively, are largely involved in the development of breast cancer (BC). The recent identification of ERα-36, a splice variant of ERα, has uncovered a new facet of this pathology. Although E...
Zhang, Lu Wang, Qiang Wang, Lijie Xie, Longxiang An, Yang Zhang, Guosen Zhu, Wan Li, Yongqiang Liu, Zhihui Zhang, Xiaochen
...
Published in
Cancer Cell International
BackgroundCutaneous melanoma is one of the most aggressive and lethal skin cancers. It is greatly important to identify prognostic biomarkers to guide the clinical management. However, it is technically challenging for untrained researchers to process high dimensional profiling data and identify potential prognostic genes in profiling datasets.Meth...
Tribukait, Bernhard
Published in
BMC Cancer
BackgroundAfter neoadjuvant chemotherapy of breast cancer pathologic complete response (pCR) indicates a favorable prognosis. Among non-selected patients, pCR is, however, achieved in only 10–30%. Early evaluation of tumour response to treatment would facilitate individualized therapy, with ineffective chemotherapy interrupted or changed. The metho...
Abdelhak, A. Huss, A. Brück, A. Sebert, U. Mayer, B. Müller, H. P. Tumani, H. Otto, M. Yilmazer-Hanke, D. Ludolph, A. C.
...
Published in
Neurological Research and Practice
BackgroundCerebral small vessel disease (CSVD) is a disorder of brain vasculature that causes various structural changes in the brain parenchyma, and is associated with various clinical symptoms such as cognitive impairment and gait disorders. Structural changes of brain arterioles cannot be visualized with routine imaging techniques in vivo. Howev...
Wu, Helen Zong Ying Thalamuthu, Anbupalam Cheng, Lesley Fowler, Christopher Masters, Colin L. Sachdev, Perminder Mather, Karen A.
Published in
Alzheimer's Research & Therapy
BackgroundPeripheral blood microRNAs (miRNA) have been identified as potential biomarkers for Alzheimer’s disease (AD). Study results have generally been inconsistent and limited by sample heterogeneity. The aim of this study is to establish candidate blood miRNA biomarkers for AD by comparing differences in miRNA expression between participants wi...
