Yoshikawa, Tomoko Hata, Jun Sakata, Satoko Nagata, Takuya Hirakawa, Yoichiro Hirooka, Yoshitaka Tsutsui, Hiroyuki Kitazono, Takanari Ninomiya, Toshiharu
Published in
Circulation journal : official journal of the Japanese Circulation Society
Atrial fibrillation (AF) is a common arrhythmia in the elderly, and causes complications such as cardioembolic stroke. Serum high-sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, has been reported to be a risk factor for developing AF in Western countries. However, few community-based studies have examined this issue in g...
Frigyesi, Attila Boström, Lisa Lengquist, Maria Johnsson, Patrik Lundberg, Oscar H. M. Spångfors, Martin Annborn, Martin Cronberg, Tobias Nielsen, Niklas Levin, Helena
...
Published in
Intensive Care Medicine Experimental
BackgroundProenkephalin A 119-159 (penKid) has been suggested as a marker of renal failure and poor outcome. We aimed to investigate the association of penKid on ICU admission with organ dysfunction and mortality in a mixed ICU population. In this retrospective, observational study, admission penKid levels from prospectively collected blood samples...
Yin, Lei Liu, Xiaotian Shao, Xuejun Feng, Tao Xu, Jun Wang, Qi Hua, Shenghao
Published in
Journal of Translational Medicine
Lung cancer is the leading cause of cancer-associated deaths accounting for 24% of all cancer deaths. As a crucial phase of tumor progression, lung cancer metastasis is linked to over 70% of these mortalities. In recent years, exosomes have received increasing research attention in their role in the induction of carcinogenesis and metastasis in the...
Yao, Feng Zhu, Zhao Feng Wen, Jun Zhang, Fu Yong Zhang, Zheng Zhu, Lun Qing Su, Guang Hao Yuan, Quan Wen Zhen, Yun Fang Wang, Xiao Dong
...
Published in
Cancer Cell International
BackgroundOsteosarcoma was the most common primary bone malignancy in children and adolescents. It was imperative to identify effective prognostic biomarkers for this cancer. This study was aimed to identify potential crucial genes of osteosarcoma by integrated bioinformatics analysis.MethodsIdentification of differentially expressed genes from pub...
Jin, Fangfang Yang, Liuqing Wang, Weixiang Yuan, Na Zhan, Shoubin Yang, Ping Chen, Xi Ma, Tonghui Wang, Yanbo
Published in
Molecular Cancer
Schading, Simon Emmenegger, Tim M. Freund, Patrick
Published in
Current Neurology and Neuroscience Reports
Purpose of ReviewTraumatic spinal cord injury (SCI) is a life-changing event with drastic implications for patients due to sensorimotor impairment and autonomous dysfunction. Current clinical evaluations focus on the assessment of injury level and severity using standardized neurological examinations. However, they fail to predict individual trajec...
Kong, Anthony Mehanna, Hisham
Published in
Current Oncology Reports
Purpose of ReviewWEE1 inhibitor has been shown to potential chemotherapy or radiotherapy sensitivity in preclinical models, particularly in p53-mutated or deficient cancer cells although not exclusively. Here, we review the clinical development of WEE1 inhibitor in combination with chemotherapy or radiotherapy with concurrent chemotherapy as well a...
Mut, Tuna Till Acar, Ömer Armutlu, Ayse Incir, Said Uhlig, Annemarie Ertuglu, Lale A. Özel, Melis Taskin, Ali Cihan Baydar, Dilek Ertoy Kanbay, Mehmet
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Published in
BMC Nephrology
BackgroundTo investigate if remote ischemic preconditioning (RIPC) can offer any renoprotective value by counteracting the deleterious effect of partial nephrectomy (PN) under warm ischemia on renal function.MethodsFour groups, each with 5 Wistar albino rats, were constructed; RIPC + PN, PN, RIPC and sham. Right nephrectomy was performed to constit...
Wang, Hui Li, Hong Yan, Qingtao Gao, Sumei Gao, Jianfang Wang, Zhenhua Sun, Yi
Published in
BMC Cancer
BackgroundA significant proportion of newly diagnosed patients with cutaneous squamous cell carcinoma (cSCC) have metastasis and eventually die of the disease, necessitating the exploration of novel biomarkers for early detection of cSCC aggressiveness, risk assessment and monitoring. Matrix metalloproteinase-13 (MMP-13) has been implicated in cSCC...
Quan, Jing Bai, Yuchen Yang, Yunbei Han, Er Lei Bai, Hong Zhang, Qi Zhang, Dahong
Published in
BMC Cancer
BackgroundThe molecular prognostic biomarkers of clear cell renal cell carcinoma (ccRCC) are still unknown. We aimed at researching the candidate biomarkers and potential therapeutic targets of ccRCC.MethodsThree ccRCC expression microarray datasets (include GSE14762, GSE66270 and GSE53757) were downloaded from the gene expression omnibus (GEO) dat...
