Ceballos, Diana M Young, Anna S Allen, Joseph G Specht, Aaron J Nguyen, Vy T Craig, Jessica A Miller, Melissa Webster, Thomas F
Published in
International journal of hygiene and environmental health
Nail polishes have evolved considerably. Toxic elements, such as lead, have been found in nail polish, and it is unclear if new finishes using metallic effect pigments may be contributing to metals exposure in nail technicians. We characterized concentrations of trace elements in 40 nail polishes, 9 technicians' urine, and 20 technicians' toenail c...
Anderson, Ryan T Choi, Hannah S J Lenz, Oliver Peters, Marion G Janssen, Harry L A Mishra, Poonam Donaldson, Eric Westman, Gabriel Buchholz, Stephanie Miller, Veronica
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Published in
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Seroclearance of hepatitis B surface antigen (HBsAg) is the desired end point of treatment for chronic hepatitis B virus (HBV) infection, according to guidelines. We performed a systematic review and meta-analysis to evaluate the strength of the association between HBsAg seroclearance and long-term clinical outcomes. We performed a systematic revie...
Morató, Xavier Garcia-Esparcia, Paula Argerich, Josep Llorens, Franc Zerr, Inga Paslawski, Wojciech Borràs, Eva Sabidó, Eduard Petäjä-Repo, Ulla E. Fernández-Dueñas, Víctor
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Published in
Translational Neurodegeneration
Objective α-Synuclein has been studied as a potential biomarker for Parkinson’s disease (PD) with no concluding results. Accordingly, there is an urgent need to find out reliable specific biomarkers for PD. GPR37 is an orphan G protein-coupled receptor that toxically accumulates in autosomal recessive juvenile parkinsonism. Here, we investigated wh...
Anand, Uttpal Adelodun, Bashir Pivato, Alberto Suresh, S. Indari, Omkar Jakhmola, Shweta Chandra Jha, Hem Jha, Pawan Kumar Tripathi, Vijay Di Maria, Francesco
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Published in
Environmental Research
According to the WHO, on October 16 2020, the spreading of the SARS-CoV-2, responsible of the COVID-19 pandemic, achieved 235 countries and territories, resulting in more than 39 million confirmed cases and 1.09 million deaths globally. Monitoring of virus outbreak is one of the main activities pursued for limiting the number of infected peoples an...
Santana, Bárbara Brasil Queiroz, Maria Alice Freitas Cerveira, Rodrigo Arcoverde Rodrigues, Claudia Mendonça da Silva Graça Amoras, Ednelza da Costa, Carlos Araújo de Sousa, Maisa Silva Ishak, Ricardo Goulart, Luiz Ricardo Vallinoto, Antonio Carlos Rosário
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Published in
BMC Infectious Diseases
Background Human T-lymphotropic virus 1 (HTLV-1) is etiologically associated with the chronic inflammatory neurodegenerative disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) Annexin A1 (AnxA1) is an anti-inflammatory protein with proposed neuroprotective and anti-neuroinflammatory functions. We hypothesized that ANXA1 gen...
Wilkinson, Carol L. Nelson, Charles A.
Published in
Molecular Autism
Background The lack of robust and reliable clinical biomarkers in Fragile X Syndrome (FXS), the most common inherited form of intellectual disability, has limited the successful translation of bench-to-bedside therapeutics. While numerous drugs have shown promise in reversing synaptic and behavioral phenotypes in mouse models of FXS, none have demo...
Witters, Peter Edmondson, Andrew C. Lam, Christina Johnsen, Christin Patterson, Marc C. Raymond, Kimiyo M. He, Miao Freeze, Hudson H. Morava, Eva
Published in
Orphanet Journal of Rare Diseases
A recent report on long-term dietary mannose supplementation in phosphomannomutase 2 deficiency (PMM2-CDG) claimed improved glycosylation and called for double-blind randomized study of the dietary supplement in PMM2-CDG patients. A lack of efficacy of short-term mannose supplementation in multiple prior reports challenge this study’s conclusions. ...
Kuerbanjiang, Aihemaijiang Maimaituerxun, Maimaitiyiming Zhang, Yanjun Li, Yiliang Cui, Gang Abuduhabaier, Aibaidula Aierken, Abuduwaili Miranbieke, Buya Anzaer, Meilikezati Maimaiti, Yusufu
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Published in
BMC Gastroenterology
Background Esophageal cancer is one of the most aggressive malignancies, and is associated with multiple genetic mutations. At present, the v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) gene mutation has been observed in esophageal cancer and is associated with poor prognosis. This study aimed to investigate the protein expression of BRAF i...
Coarelli, Giulia Darios, Frédéric Petit, Emilien Dorgham, Karim Adanyeguh, Isaac Petit, Elodie Brice, Alexis Mochel, Fanny Durr, Alexandra
Neurofilament light chain (NfL) is a marker of brain atrophy and predictor of disease progression in rare diseases such as Huntington Disease, but also in more common neurological disorders such as Alzheimer's disease. The aim of this study was to measure NfL longitudinally in autosomal dominant spinocerebellar ataxias (SCAs) and establish correlat...
Berger, Karoline Rhost, Sara Rafnsdóttir, Svanheiður Hughes, Éamon Magnusson, Ylva Ekholm, Maria Stål, Olle Rydén, Lisa Landberg, Göran
Published in
BMC Cancer
Background The growth factor progranulin has been implicated in numerous biological processes such as wound healing, inflammation and progressive tumorigenesis. Both progranulin and its receptor sortilin are known to be highly expressed in subgroups of breast cancer and have been associated with various clinical properties including tamoxifen resis...
