Published in Journal of Physics: Conference Series
Heterocyclic compounds are an important class of organic compound. Owing to their usefulness in synthetic processes, numerous heterocyclic compounds are currently known, and this number is growing quickly. The uses of heterocyclic compounds are numerous. They are mostly used as veterinary goods, agricultural chemicals, and medications. Additionally...
Oligosaccharides are the ubiquitous molecules of life. In order to translate human bioglycosylation into clinical applications, homogeneous samples of oligosaccharides and glycoconjugates can be obtained by chemical, enzymatic or other biological methods for systematic studies. However, the structural complexity and diversity of glycans and their c...
Cistanche deserticola is a traditional and precious Chinese herbal medicine, known as "desert ginseng", with anti-inflammatory, anti-oxidant, improving immunity, nourishing the kidneys and other pharmacological effects. Its chemical components mainly include phenylethanol glycosides, iridoids, polysaccharides and volatile components, among which po...
Published in Iranian journal of pharmaceutical research : IJPR
Impaired cell cycle regulation and disturbance in signal transduction pathway are two major causes of a condition defined as cancer, one of the significant reasons for mortality worldwide. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been commonly used as anticancer agents, and the majority of this medications posses...
Published in Angewandte Chemie (International Ed. in English)
Fully stereocontrolled synthesis of the algae differentiation factor (−)‐thallusin was achieved by employing a 6‐ endo ‐cyclization and effective late‐stage sp2–sp2‐coupling using non‐toxic reagents. Quantitative phenotype profiling in the alga Ulva mutabilis gave an EC50 of 4.8 pM. SAR investigations of derivatives uncovered two functionally disti...
Published in Asian Pacific Journal of Cancer Prevention : APJCP
Objective: Croton tiglium L. seeds were studied against colon cancer induced chemically in rats after incorporating silver nanoparticles (Ag-NPs) but the body has no the ability to discrete silver or silver ions. Therefore, the present study was designed to reveal the biological activities of different C. tiglium L. seeds extracts incorporated with...
Published in Journal of Polymer Research
In this study, thermal and dielectric properties of chalcone methacrylamide polymers containing methoxy group in side chain were studied. At first the chalcone compounds abbreviated as CHAL1, CHAL2, and CHAL3 containing the methoxy group in the side chain were synthesized. Then, the monomers abbreviated as M1, M2 and M3 were synthesized by the reac...
Published in ChemMedChem
We describe the convergent synthesis of a 5-O-β-D-ribofuranosyl-based apramycin derivative (apralog) that displays significantly improved antibacterial activity over the parent apramycin against wild-type ESKAPE pathogens. In addition, the new apralog retains excellent antibacterial activity in the presence of the only aminoglycoside modifying enzy...
Published in Chaos (Woodbury, N.Y.)
Near-shore water along the North-West African margin is one of the world's major upwelling regions. It is associated with physical structures of oceanic fronts which influence the biological productivity. The study of these coherent structures in connection with chlorophyll concentration data is of fundamental importance for understanding the spati...
Published in Journal of nanoscience and nanotechnology
The title compound (3-methyl-1,5-dioxaspiro[5.5]undecan-3-yl)methanol (C11H20O3, Mr = 200.27) was synthesized by the aldol reaction of 1,1,1-tris(hydroxymethyl)ethane with cyclohexane in the presence of sulfonated carbon in cyclohexane and N, N-dimethylbenzamide, and its structure was characterized by melting points, elemental analysis, IR spectra,...
