The CPES (Channel Payments for Ecosystem Services) project developed PES schemes remunerating farmers their activities in improving water quality by reducing the emissions of nutrients (both nitrogen and phosphorus) or erosion from agricultural activities. Catchment-wide approaches were tested six case studies, ecology, hydrogeology, agroeconomy, l...
Published in Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
Essential thrombocythemia is one of the chronic myeloproliferative neoplasms characterized by clonal proliferation of myeloid cells with variable morphological maturation and hematopoietic activity.It is characterized by excessive clonal platelet production with a tendency to thrombosis and bleeding. Thrombocytapheresıs is the removal of platelets ...
Post-translational modifications (PTMs) add a major degree of complexity to the proteome and are essential controllers of protein homeostasis. Amongst the hundreds of PTMs identified, ubiquitin and ubiquitin-like (UBL) modifications are recognized as key regulators of cellular processes through their ability to affect protein–protein interactions, ...
Published in Nature communications
Most eukaryotic proteins are N-terminally acetylated, but the functional impact on a global scale has remained obscure. Using genome-wide CRISPR knockout screens in human cells, we reveal a strong genetic dependency between a major N-terminal acetyltransferase and specific ubiquitin ligases. Biochemical analyses uncover that both the ubiquitin liga...
The hydrothermal production of chitosan from the carapaces of gray shrimp was carried out, and the obtained material was characterized via X-ray diffraction analysis, infrared spectroscopy, and pH zero-charge point, giving the expected results. Orange G dye adsorption onto synthetized chitosan was investigated in a batch system, the kinetic study w...
Copper(I) halides are well-known for their structural diversity and rich photoluminescence properties, showing great potential the development of solid-state lighting technology. A series four molecular copper iodide clusters based on [Cu4I4] cubane geometry is reported. Among them, [Cu8I8] octanuclear rare resulting from dimerization tetranuclear ...
A series of platinum diimine-dithiolene complexes with a 5,6-dihydro-1,4-dithiin-2,3-dithiolato (dddt2-) dithiolene ligand and bipyridine carrying tris-alkoxyphenyl fragments connected through an ester linker (bpyCn, n = 8, 12, 16, 10(s), 20) (Scheme 1) has been developed. The mesomorphic properties the ligands have investigated by combination DSC,...
Published in iScience
The colonic mucosal barrier protects against infection, inflammation, and tissue ulceration. Composed primarily of Mucin-2, proteolytic erosion of this barrier is an invariant feature of colitis; however, the molecular mechanisms are not well understood. We have applied a recurrent food poisoning model of acquired inflammatory bowel disease using S...
Vacuum membrane distillation (VMD) is a compelling technique for desalinating water because it exhibits superior pure permeability at lower operating temperatures compared to other technologies. This leads reduced energy consumption, heat loss via conduction across the surface, and minimal transfer through due low pressure on permeate side. Detaile...
To better understand the stoichiometry of CD95L required to trigger apoptotic and nonapoptotic signals, we generated several concatemers from dimer hexamer conjugated via a flexible link (GGGGS)2 . These ligands reveal that although hexameric structure is best cell death, sufficient induce response in CD95-sensitive Jurkat cells. Interestingly, onl...
