Borges, Debora Azevedo Cid, Yara Peluso Magalhães, Viviane de Sousa Alves, Melina Cardilo Campos Ferreira, Thais Paes Bonfim, Isabelle Vilela Lima, Emily Andressa Santos de Freitas, Juliana Pereira Scott, Fabio Barbour
Published in
Parasites & Vectors
Background Brazilian spotted fever (BSF), the most lethal tick-borne disease in the Western Hemisphere, is caused by the bacterium Rickettsia rickettsii and transmitted by the bite of Amblyomma sculptum . Capybaras are considered primary hosts of this tick and amplifier hosts of R. rickettsii , generating new infected lineages of A. sculptum in BSF...
Salawi, Ahmad
Published in
Drug Delivery
Self-emulsifying drug delivery systems (SEDDS) are a proven method for poorly soluble substances works by increasing the solubility and bioavailability. SEDDS and isotropic mixtures, are composed of oils, surfactants, and occasionally cosolvents. The ability of these formulations and methods to produce microemulsions or fine oil-in-water (o/w) emul...
Chen, Hui Zhao, Ying Li, Ran Chen, Bin Luo, Zhiman Shi, Yaling Wang, Kaiqiu Zhang, Wei Lin, Shiyuan
Published in
Journal of pharmaceutical sciences
In this study, novel Panax notoginseng saponins (PNS)-loaded nanoparticles coated with the Trimethyl chitosan (TMC) derivatives TMC-VB12 and TMC-Cys (PPTT-NPs) were developed to improve the oral absorption of the constituents. PPTT-NPs were prepared by the double emulsion method and showed different encapsulation effects on the major components, in...
Belháčová-Minaříková, Michaela Allan, Ian Vrana, Branislav
Published in
Environmental science and pollution research international
Contamination of aquatic ecosystems by hydrophobic organic contaminants (HOCs) is often assessed based on their concentrations in riverbed sediment and suspended particulate matter (SPM). However, total HOC concentration (CTOT) in sediment or SPM is of limited value for evaluating the exposure of benthic or pelagic organisms. The accessible HOC con...
Feidt, Cyril El Wanny, Nadine Ranguin, Ronald Gaspard, Sarra Baroudi, Moomen Yacou, Christelle Rychen, Guido Delannoy, Matthieu
Published in
Environmental geochemistry and health
Chlordecone (Kepone) (CLD) is a highly persistent pesticide formerly used in the French West Indies. High levels of this pesticide may be found in soils and constitute a subsequent source of contamination for outdoor-reared animals due to involuntary ingestion of consistent amounts of soil. In that context, carbonaceous materials may be used to ame...
Eriksen, Jonas Borregaard Christensen, Stine Bredow Bauer-Brandl, Annette Brandl, Martin
Published in
Journal of pharmaceutical sciences
We aimed to understand the impact of the interplay between bile salts and cyclodextrins on the dissolution-permeation of poorly soluble drug compounds with a moderate-strong binding constant to cyclodextrin. Phase diagrams were prepared on the chosen model compound albendazole in phosphate buffer, fasted state simulated intestinal fluid (FaSSIF), a...
Abou-Elwafa Abdallah, Mohamed Harrad, Stuart
Published in
Environmental research
The chlorinated organophosphate flame retardants (Cl-PFRs): tris-(2-chloroethyl)-phosphate (TCEP), tris-(1-chloro-2-propyl)-phosphate (TCIPP) and tris-(1,3-dichloropropyl)-phosphate (TDCIPP), have been widely used in upholstered furniture despite their carcinogenic potential. Although Cl-PFRs are mainly added to furniture foam, they are present in ...
Zheng, Yinghao Wang, Yun Xia, Mengyu Gao, Ya Zhang, Lan Song, Yanan Zhang, Cun
Published in
Drug delivery and translational research
Fast development of combination of nanotechnology with traditional Chinese medicine (TCM) broadens the field of application of TCM. Besides, it increases the research ideas and contributes to TCM modernization. As expected, TCM will be developed into the nanodrug delivery system by nanotechnology with careful design, which will enhance the medicina...
Torri, Giangiacomo Naggi, Annamaria Lichtfouse, Eric Crini, Grégorio
National audience
Pham, Nhung Thi Ha Babcsányi, Izabella Farsang, Andrea
Published in
Environmental geochemistry and health
Potentially toxic elements (PTEs), such as Cu, Zn, Pb, Ni, Cr, and Co, can accumulate in vineyard soils due to repeated uses of inorganic pesticides and chemical or organic fertilizers. In sloping vineyards, PTEs can also be moved by soil erosion resulting in their accumulation in low-energy zones within the landscape, adversely affecting the soil ...
