Choudhury, Shuvasish Moulick, Debojyoti Saikia, Purbajyoti Mazumder, Muhammed Khairujjaman
Published in
Medical journal, Armed Forces India
Coronavirus disease 2019 (COVID-19) has already affected 2883603 and killed 198842 people, as of April 27, 2020. Because there is no specific therapeutic drug, drug repurposing has been proposed. RNA-dependent RNA polymerase (RdRp) is a promising drug against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to control its replication, a...
Hernández-Aguilar, Itandehui Lorenzo, Consuelo Santos-Moreno, Antonio Naranjo, Eduardo J Navarrete-Gutiérrez, Darío
Published in
Viruses
The SARS-CoV-2 coronavirus is the focus of attention as it has caused more than three million human deaths globally. This and other coronaviruses, such as MERS-CoV, have been suggested to be related to coronaviruses that are hosted in bats. This work shows, through a bibliographic review, the frequency of detection of coronavirus in bats species of...
Di Stefano, Mariantonietta Sarno, Michelina Faleo, Giuseppina Farhan Mohamed, Ahmed Mohamed Lipsi, Maria Rosaria De Nittis, Rosella Bruno, Serena Rita De Feo, Lucia Granato, Tommaso Corso, Gaetano
...
Published in
Acta Haematologica
Recently, a significant cluster of pneumonia caused by a novel betacoronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) was described initially in China and then spread throughout the world. Like other coronaviridae, the viral transmission occurs mainly through droplets. In addition, the virus has been detected in different cli...
de Oliveira, Fernando Anselmo Nucci, Mariana Penteado Rego, Gabriel Nery de Albuquerque Alves, Arielly da Hora Marti, Luciana Cavalheiro Nucci, Leopoldo Penteado Mamani, Javier Bustamante Gamarra, Lionel Fernel
Published in
Einstein
The objective of this study was to highlight the global scientific effort to fight the SARS-CoV-2, addressing the preliminary results of passive immunization through convalescent plasma. We performed a search at the major databases of interventional clinical trial protocols about the transfusion of convalescent plasma in patients with COVID-19, as ...
Araújo, Claudio Gil Soares de
Brazão, Stephani Correia Autran, Lis Jappour Lopes, Rosane de Oliveira Scaramello, Christianne Brêtas Vieira Brito, Fernanda Carla Ferreira de Motta, Nadia Alice Vieira
Abstract Chloroquine (CQ) and Hydroxychloroquine (HCQ) are antimalarial drugs, with anti-inflammatory properties that justify their use in the treatment of systemic lupus erythematosus and rheumatic diseases. A pandemic caused by the new coronavirus led the entire world’s scientific community to look for drugs already available on the market, capab...
Pires, Gabriel Natan Bezerra, Andréia Gomes de Oliveira, Thainá Baenninger Chen, Samuel Fen I Malfatti, Victor Davis Apostolakis de Mello, Victoria Feiner Ferreira Niyama, Alyne Pinto, Vitor Luiz Selva Andersen, Monica Levy Tufik, Sergio
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Published in
Einstein
Objective: To carry out a scoping review of the meta-analyses published regarding about coronavirus disease 2019 (COVID-19), evaluating their main characteristics, publication trends and methodological quality. Methods: A bibliometric search was performed in PubMed®, Scopus and Web of Science, focusing on meta-analyses about COVID-2019 disease. Bib...
Sumi, Daniel Vaccaro Loureiro, Rafael Maffei Collin, Simon Michael Deps, Patrícia Duarte Bezerra, Lorena Lima Gomes, Regina Lúcia Elia Daniel, Mauro Miguel
Published in
Einstein
Objective: To analyze computed tomography scans of paranasal sinuses of a series of patients with coronavirus disease 2019, and correlate the findings with the disease. Methods: Computed tomography scans of 95 adult patients who underwent a polymerase chain reaction test for severe acute respiratory syndrome coronavirus 2 were analyzed. Clinical da...
Li, Linmiao Wang, Xiaohu Hua, Yan Liu, Ping Zhou, Jiabin Chen, Jing An, Fuyu Hou, Fanghui Huang, Wenzhong Chen, Jinping
...
Published in
Frontiers in Microbiology
The coronavirus disease 2019 (COVID-19) outbreak has significantly affected international public health safety. It has been reported that the pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19, could originate from bats and utilize the Malayan pangolin (Manis javanica) as an intermediate host. To gain furth...
Azevedo, Rafael Bellotti Botelho, Bruna Gopp Hollanda, João Victor Gonçalves de Ferreira, Leonardo Villa Leão Andrade, Letícia Zarur Junqueira de Oei, Stephanie Si Min Lilienwald Mello, Tomás de Souza Muxfeldt, Elizabeth Silaid
Abstract Acute cardiac injury is associated with higher mortality in patients with the novel coronavirus disease-2019 (COVID-19) and the exact etiology can be challenging to diagnose in the emergency setting during the pandemic. From a pathophysiological perspective, SARS-CoV-2 infection is characterized by an overproduction of inflammatory cytokin...
