Qu, Yishan Zhang, Lizi An, Shucheng Tai, Fadao Qiao, Hui
Published in
Cognitive, affective & behavioral neuroscience
Empathy is a potential motivation for prosocial behaviors that is related to many psychiatric diseases, such as major depressive disorder; however, its neural mechanisms remain unclear. To elucidate the relationship between empathy and stress, we established a chronic stress contagion (SC) procedure combined with chronic unpredictable mild stress (...
Leppla, Chris A Keyes, Laurel R Glober, Gordon Matthews, Gillian A Batra, Kanha Jay, Maya Feng, Yu Chen, Hannah S Mills, Fergil Delahanty, Jeremy
...
Published in
Psychopharmacology
The basolateral amygdala (BLA) and medial geniculate nucleus of the thalamus (MGN) have both been shown to be necessary for the formation of associative learning. While the role that the BLA plays in this process has long been emphasized, the MGN has been less well-studied and surrounded by debate regarding whether the relay of sensory information ...
Loh, Maxine K Rosenkranz, J Amiel
Published in
Cerebral cortex (New York, N.Y. : 1991)
Nucleus accumbens (NAc) neurons integrate excitatory inputs from cortical and limbic structures, contributing to critical cognitive functions, including decision-making. As these afferents mature from adolescence through adulthood, incoming signals to the NAc may summate differently between age groups. Decision-making evaluates both reward and risk...
Li, Hao Namburi, Praneeth Olson, Jacob M Borio, Matilde Lemieux, Mackenzie E Beyeler, Anna Calhoon, Gwendolyn G Hitora-Imamura, Natsuko Coley, Austin A Libster, Avraham
...
Published in
Nature
The ability to associate temporally segregated information and assign positive or negative valence to environmental cues is paramount for survival. Studies have shown that different projections from the basolateral amygdala (BLA) are potentiated following reward or punishment learning1-7. However, we do not yet understand how valence-specific infor...
Servonnet, Alice Rompré, Pierre-Paul Samaha, Anne-Noël
Published in
Behavioural brain research
Reward-associated conditioned stimuli (CSs) can acquire predictive value, evoking conditioned approach behaviours that prepare animals to engage with forthcoming rewards. Such CSs can also acquire conditioned reinforcing value, becoming attractive and pursued. Through their conditioned effects, CSs can promote adaptive (e.g., locating food) but als...
Koekkoek, L L Masís-Vargas, A Kool, T Eggels, L van der Gun, L L Lamuadni, K Slomp, M Diepenbroek, C Kalsbeek, A la Fleur, S E
...
Published in
Nutritional neuroscience
Objectives: We have previously shown that the combined consumption of fat and a sucrose solution induces overeating, and there is evidence indicating that sucrose drinking directly stimulates fat intake. One neurochemical pathway by which sucrose may enhance fat intake is through the release of endogenous opioids in the nucleus accumbens (NAC).Meth...
Djerdjaj, Anthony Ng, Alexandra J Rieger, Nathaniel S Christianson, John P
Published in
Behavioural brain research
Vocalizations, chemosignals, and behaviors are influenced by one's internal affective state and are used by others to shape social behaviors. A network of interconnected brain structures, often called the social behavior network or social decision-making network, integrates these stimuli and coordinates social behaviors, and in-network connectivity...
Itoh, Ryusei Ishikawa, Yudai Tamano, Haruna Takeda, Atsushi
Published in
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Beta-adrenergic receptors in the basolateral amygdala play an essential role in fear memory, while the physiological role of intracellular Zn2+ remains to be clarified. Intracellular Zn2+ level was decreased 5 min after local injection of 500 μM isoproterenol (2 μl), a nonselective beta-adrenergic receptor agonist into the basolateral amygdala, sug...
Keefer, Sara E Petrovich, Gorica D
Published in
Neurobiology of learning and memory
Through Pavlovian appetitive conditioning, environmental cues can become predictors of food availability. Over time, however, the food, and thus the value of the associated cues, can change based on environmental variations. This change in outcome necessitates updating of the value of the cue to appropriately alter behavioral responses to these cue...
Tokutake, Tomohiro Asano, Takashi Miyanishi, Hajime Nakaya, Shigetoshi Izuo, Naotaka Nitta, Atsumi
Published in
Neurochemical research
The number of cannabis users is increasing in the world. However, the mechanisms involved in the psychiatric effects and addiction formation remain unclear. Medical treatments against cannabis addiction have not yet been established. Δ9-Tetrahydrocannabinol (THC), the main active substance in cannabis, binds and affects cannabinoid type 1 receptors...
