Ha, Le Ngoc Iravani, Amir Nhung, Nguyen Thi Hanh, Ngo Thi Minh Hutomo, Febby Son, Mai Hong
Published in
Cancer Imaging
BackgroundIn this study, we investigated the relationship between clinicopathologic factors, BRAFV600E mutation status and [18F] F-fluoro-2-deoxyglucose (FDG) avidity in patients with radioiodine (RAI)-negative recurrent or metastatic differentiated thyroid cancer (DTC).MethodsFrom 2015 to 2018 all patients with suspected recurrent or metastatic ra...
Suzuki, Hidenori Sasaki, Eiichi Nakamura, Ryota Sawabe, Michi Hagiwara, Sumitaka Hyodo, Ikuo Hanai, Nobuhiro
Published in
Clinical case reports
This case report describes a mandibular ameloblastoma with both BRAF V600E mutation and rare hypercalcemia. The patient without distant metastasis underwent subtotal mandibulectomy using double flaps of fibula and anterolateral thigh. A whole body computed tomography scan taken 69 months after surgery revealed neither recurrence nor metastasis. © 2...
Di Stefano, Anna Luisa Guyon, David Sejean, Karine Feuvret, Loic Villa, Chiara Berzero, Giulia Desforges Bullet, Virginie Halimi, Emmanuel Boulin, Anne Baussart, Bertrand
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International audience
Chakraborty, Dhritiman Shakya, Sunil Ballal, Sanjana Agarwal, Shipra Bal, Chandrasekhar
Published in
Journal of Pediatric Endocrinology and Metabolism
Objectives The primary objective of this study was to determine the prevalence of BRAF V600E and TERTpromoter mutations in paediatric and young adult patients with papillary thyroid carcinoma (PTC) and the secondary objective, to assess their association with clinicopathological features. Methods Patients ≤20 years who underwent surgery for differe...
Hayase, Tomomi Saito, Shiori Shioda, Yoko Imamura, Toshihiko Watanabe, Kenichiro Ohki, Kentaro Yoshioka, Takako Oh, Yukiko Kawahara, Yuta Niijima, Hitomi
...
Published in
International journal of hematology
In Langerhans cell histiocytosis (LCH), somatic gene mutations in the mitogen-activated protein kinase pathway have been identified in more than 80% of cases in Western countries, in which mutually exclusive BRAF and MAP2K1 mutations are involved. Among them, BRAF V600E mutation is the major contributor (50-60%). In 59 patients (50 children and nin...
Dong, Stephen Khedro, Tarek Ward, Pamela Dubeau, Louis Yaghmour, Bassam Siddiqi, Imran Yaghmour, George
Published in
British journal of haematology
Dawoud, Fakhry M Naylor, Ryan M Giannini, Caterina Swanson, Amy A Meyer, Fredric B Uhm, Joon H
Published in
Clinical neurology and neurosurgery
Tateishi, Kensuke Ikegaya, Naoki Udaka, Naoko Sasame, Jo Hayashi, Takahiro Miyake, Yohei Okabe, Tetsuhiko Minamimoto, Ryogo Murata, Hidetoshi Utsunomiya, Daisuke
...
Published in
Acta Neuropathologica Communications
We present a case of a 14-year old boy with tumor-associated refractory epilepsy. Positron emission tomography imaging demonstrated a region with heterogeneous high 11C-methionine uptake and a region with homogenous low 18F-fluorodeoxyglucose uptake within the tumor. Histopathological and genomic analyses confirmed the tumor as BRAF V600E-mutated p...
Shi, Chenlei Cao, Jia Shi, Tiefeng Liang, Meihua Ding, Chao Lv, Yichen Zhang, Weifeng Li, Chuanle Gao, Wenchao Wu, Gang
...
Published in
World Journal of Surgical Oncology
BackgroundThe incidence of thyroid cancer is increasing worldwide. This study investigated the association of B-type RAF kinase (BRAF)V600E mutation status, the expression of BRAF-activated long non-coding RNA (BANCR) and microRNA miR-9, and the clinicopathological features of papillary thyroid carcinoma (PTC).MethodsClinicopathological data for PT...
Li, Gui-you Tan, Hai-long Chen, Pei Hu, Hui-Yu Liu, Mian Ou-yang, Deng-jie Khushbu, Rooh-afza Pun, Deepak Li, Jin-dong Zhang, Zhi-peng
...
Published in
Cancer Management and Research
Background Therapeutic lateral neck dissection (LND) is recommended in papillary thyroid carcinoma (PTC) patients with clinically lateral lymph node metastasis (LLNM), whether underwent level V LND remains controversial for lacking of sensitive predicting system. BRAF V600E mutation is associated with aggressive tumor behavior, recurrence, and dise...
