Zhang, Shanshan Yang, Qian Defoirdt, Tom
Published in
Microbiology Spectrum
Indole signaling is viewed as a potential target for antivirulence therapy against antibiotic-resistant pathogens because of its link with the production of virulence factors. This study examined the antimicrobial and antivirulence properties of 44 indoles toward Vibrio campbellii. Based on the results, 17 halogenated indole analogues were selected...
Wu, G Grassi, P MacIntyre, D Molina, BG Sykes, L Kundu, S Hsiao, C-T Khoo, K-H Bennett, P Dell, A
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Human cervicovaginal fluid (CVF) is a complex, functionally important and glycan rich biological fluid, fundamental in mediating physiological events associated with reproductive health. Using a comprehensive glycomic strategy we reveal an extremely rich and complex N-glycome in CVF of pregnant and non-pregnant women, abundant in paucimannose and h...
Singh, Richard Raj Wesemael, Wim M. L.
Published in
Frontiers in Plant Science
The root-knot nematode, Meloidogyne incognita, is a major pest in tomato production. Paenibacillus polymyxa, which is primarily found in soil and colonizing roots, is considered a successful biocontrol organism against many pathogens. To evaluate the biocontrol capacity of P. polymyxa LMG27872 against M. incognita in tomato, experiments were conduc...
p., janneke
Akkermansia muciniphila is a champion of mucin degradation in the human gastrointestinal tract. Here, we report the isolation of six novel strains from healthy human donors and their genomic, proteomic and physiological characterization in comparison to the type-strains A. muciniphila MucT and A. glycaniphila PytT. Complete genome sequencing reveal...
Bossaert, Sofie; 118593; Kocijan, Tin; 137170; Winne, Valerie; 106544; Schlich, Johanna; 79857; Herrera-Malaver, Beatriz; Verstrepen, Kevin J; 31931; Van Opstaele, Filip; 59212; De Rouck, Gert; 59216; Crauwels, Sam; 68938; Lievens, Bart; 19097;
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Sour beers produced by barrel-aging of conventionally fermented beers are becoming increasingly popular. However, as the intricate interactions between the wood, the microbes and the beer are still unclear, wood maturation often leads to inconsistent end products with undesired sensory properties. Previous research on industrial barrel-aging of bee...
Janssens, Lizanne; Van de Maele, Marlies; 138379; Delnat, Vienna; 91659; Theys, Charlotte; 130183; Mukherjee, Shinjini; 103439; De Meester, Luc; Stoks, Robby; 34380;
Exposure to pesticides can have detrimental effects on aquatic communities of non-target species. Populations can evolve tolerance to pesticides which may rescue them from extinction. However, the evolution of tolerance does not always occur and insights in the underlying mechanisms are scarce. One understudied mechanism to obtain pesticide toleran...
Ferreira, Rute; Sousa, Claudia; Goncalves, Raquel FS; Pinheiro, Ana Cristina; Oleastro, Monica; Wagemans, Jeroen; 61978; Lavigne, Rob; 24787; Figueiredo, Ceu; Azeredo, Joana; Melo, Luis DR;
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Helicobacter pylori, a significant human gastric pathogen, has been demonstrating increased antibiotic resistance, causing difficulties in infection treatment. It is therefore important to develop alternatives or complementary approaches to antibiotics to tackle H. pylori infections, and (bacterio)phages have proven to be effective antibacterial ag...
Kean, IRL Wagner, J Wijeyesekera, A De Goffau, M Thurston, S Clark, JA White, DK Ridout, J Agrawal, S Kayani, R
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Broad-spectrum antimicrobial use during the treatment of critical illness influences gastrointestinal fermentation endpoints, host immune response and metabolic activity including the conversion of primary to secondary bile acids. We previously observed reduced fermentation capacity in the faecal microbiota of critically ill children upon hospital ...
Zhang, Shanshan Yang, Qian Fu, Songzhe Janssen, Colin R Eggermont, Mieke Defoirdt, Tom
Published in
Scientific reports
Indole signaling plays an important role in bacterial pathogenesis. In this study, the impact of indole on biofilm formation, swimming and swarming motility were explored in Vibrio tasmaniensis LGP32 and Vibrio crassostreae J2-9, two model pathogens of bivalves. The results showed that indole decreased swimming and swarming motility in both strains...
van den, pieter
Functional amino acids supplementation to farm animals is considered to not only be beneficial by regulating intestinal barrier, oxidative stress, and immunity, but potentially also by impacting the gut microbiota. The impact of amino acids on a piglet-derived colonic microbiota was evaluated using a 48-h in vitro batch incubation strategy. The com...
