Pillai, Sindhu C Borah, Ankita Jacob, Eden Mariam Kumar, D Sakthi
Published in
Drug delivery
Atherosclerosis is Caesar's sword, which poses a huge risk to the present generation. Understanding the atherosclerotic disease cycle would allow ensuring improved diagnosis, better care, and treatment. Unfortunately, a highly effective and safe way of treating atherosclerosis in the medical community remains a continuous challenge. Conventional tr...
Guilleron, Céline Abraham, Pierre Beaune, Bruno Pouliquen, Camille Henni, Samir Durand, Sylvain
Published in
Scientific Reports
The ways in which locations of ischemia and ischemic pain affect spatiotemporal gait parameters and leg electromyographic activity during walking have never been investigated in patients with peripheral arterial disease presenting intermittent claudication. Two groups were classified according to unilateral location of ischemia (distal, n = 10, or ...
Deshotels, Matthew R. Virani, Salim S. Ballantyne, Christie M.
Published in
Current Cardiology Reports
Purpose of ReviewThe 2015 American College of Cardiology (ACC)/American Heart Association (AHA) Focused Update of Secondary Prevention Lipid Performance Measures removed low-density lipoprotein cholesterol (LDL-C) assessment as a performance measure. This review discusses the evidence supporting the importance of lipid monitoring in the secondary p...
Laffin, Luke J. Bakris, George L.
Published in
Current Cardiology Reports
Purpose of ReviewThe incidence of chronic kidney disease is increasing worldwide, and the previously decreasing incidence of cardiovascular disease has now plateaued. Understanding the intersection of both heart and kidney disease is crucial.Recent FindingsChronic kidney disease and cardiovascular disease share common risk factors and specific path...
Li, Yanhong Shi, Guiying Han, Yunlin Shang, Haiquan Li, Huiwu Liang, Wei Zhao, Wenjie Bai, Lin Qin, Chuan
Published in
Stem Cell Research & Therapy
BackgroundAtherosclerosis (AS) is a complex disease caused in part by dyslipidemia and chronic inflammation. AS is associated with serious cardiovascular disease and remains the leading cause of mortality worldwide. Mesenchymal stem cells (MSCs) have evolved as an attractive therapeutic agent in various diseases including AS. Human umbilical cord M...
Huang, Haomin Yu, Xiaolong Li, Lamei Shi, Ganwei Li, Feng Xiao, Jianqiang Yun, Zhihua Cai, Gaojun
Published in
Lipids in Health and Disease
BackgroundDyslipidaemia plays an important role in coronary atherosclerotic disease (CAD). The relationship between the atherogenic index of plasma (AIP) and CAD in elderly individuals was explored in this study.MethodsElderly individuals (age ≥ 65 years) who underwent coronary angiography from January 2016 to October 2020 were consecutively enroll...
Bullenkamp, Jessica Mengoni, Veronica Kaur, Satdip Chhetri, Ismita Dimou, Paraskevi Astroulakis, Zoë M J Kaski, Juan Carlos Dumitriu, Ingrid E
Published in
Cardiovascular research
Inflammation has important roles in atherosclerosis. CD4+CD28null (CD28null) T cells are a specialized T lymphocyte subset that produce inflammatory cytokines and cytotoxic molecules. CD28null T cells expand preferentially in patients with acute coronary syndrome (ACS) rather than stable angina and are barely detectable in healthy subjects. Importa...
Riad, Mohamed
Published in
The Egyptian Heart Journal
BackgroundCoronary artery disease (CAD) is a dilemma and a serious cause of morbidity and mortality worldwide. Since CAD has been seen in people without the conventional risk factors like smoking, diabetes, and hypertension, the infectious theory being a risk factor has arisen.Main bodyHelicobacter pylori (HP) infection is the most common infection...
Baradaran, Hediyeh Foster, Tyrel Harrie, Paul McNally, J Scott Alexander, Matthew Pandya, Ankur Anzai, Yoshimi Gupta, Ajay
Published in
Neuroradiology
Extracranial ICA imaging has largely focused on the degree of luminal stenosis, but recent advances suggest specific plaque features are crucial in stroke risk assessment. We evaluated the current state of reporting carotid plaque features on neck CTAs at an academic institution. In this retrospective observational study, we included neck CTAs perf...
Cong, Li Xie, Xiaolin Liu, Sujuan Xiang, Liping Zhang, Yong Cao, Jianguo Fu, Xiaohua
Published in
International immunopharmacology
Promoting plaque stability is of great significance for prevention and treatment of cardiovascular diseases. 7-difluoromethoxy-5,4'-dimethoxygenistein (DFMG) is a novel active compound synthesized using genistein, which exerts anti-atherosclerotic effect. In this study, we evaluated effects of DFMG on plaque stability in ApoE-/- mice fed with high ...
