Vogelberg, Christian Goldstein, Stanley Graham, LeRoy Kaplan, Alan de la Hoz, Alberto Hamelmann, Eckard
Published in
Respiratory Research
Diagnosing and treating asthma in paediatric patients remains challenging, with many children and adolescents remaining uncontrolled despite treatment. Selecting the most appropriate pharmacological treatment to add onto inhaled corticosteroids (ICS) in children and adolescents with asthma who remain symptomatic despite ICS can be difficult. This l...
Jiang, Jun-xia Shen, Hui-juan Guan, Yan Jia, Yong-liang Shen, Jian Liu, Qi Xie, Qiang-min Yan, Xiao-feng
Published in
Respiratory Research
Airway remodeling consists of the structural changes of airway walls, which is often considered the result of longstanding airway inflammation, but it may be present to an equivalent degree in the airways of children with asthma, raising the need for early and specific therapeutic interventions. The arachidonic acid cytochrome P-450 (CYP) pathway h...
Boudewijns, Esther A. Claessens, Danny van Schayck, Onno C. P. Keijsers, Lotte C. E. M. Salomé, Philippe L. in ‘t Veen, Johannes C. C. M. Bilo, Henk J. G. Gidding-Slok, Annerika H. M.
Published in
BMC Family Practice
BackgroundNumerous instruments have been developed to assess patient reported outcomes; most approaches however focus on a single condition. With the increasing prevalence of multimorbidity, this might no longer be appropriate. Moreover, a more comprehensive approach that facilitates shared decision making and stimulates self-management is most lik...
Liao, Yifang Li, Ping Wang, Yanxia Chen, Hong Ning, Shangwei Su, Dongju
Published in
Respiratory Research
BackgroundAsthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases. However, there is little known about the profiles of long non-coding RNA and the long non-coding RNA related competing endogenous RNA network in asthma...
Pakkasela, Johanna Ilmarinen, Pinja Honkamäki, Jasmin Tuomisto, Leena E. Andersén, Heidi Piirilä, Päivi Hisinger-Mölkänen, Hanna Sovijärvi, Anssi Backman, Helena Lundbäck, Bo
...
Published in
BMC Pulmonary Medicine
BackgroundOnset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in relation to allergy. The purpose of the study was to assess age-specific incidence of allergic and non-allergic asthma.MethodsQuestionnaires were sent to 8000 randomly selected recip...
Waggoner, Stephen N.
Published in
Current Allergy and Asthma Reports
Purpose of ReviewThis review is focused on the existing evidence for circadian control of innate and adaptive immune responses to provide a framework for evaluating the contributions of diurnal rhythms to control of infections and pathogenesis of disease.Recent FindingsCircadian rhythms driven by cell-autonomous biological clocks are central to inn...
Denholm, Rachel van der Werf, Esther T. Hay, Alastair D.
Published in
Respiratory Research
BackgroundAntibiotics are overused in patients with acute lower respiratory tract infections (ALRTIs), but less is known about their use in patients with asthma, or the use of asthma medication for ALRTI in patients without asthma. Our aim was to describe the frequency, variation and drivers in antibiotic and asthma medication prescribing for ALRTI...
Zhang, Lijia Borish, Larry Smith, Anna Somerville, Lindsay Albon, Dana
Published in
Allergy, Asthma & Clinical Immunology
BackgroundCystic fibrosis (CF) is characterized by inflammation, progressive lung disease, and respiratory failure. Although the relationship is not well understood, patients with CF are thought to have a higher prevalence of asthma than the general population. CF Foundation (CFF) annual registry data in 2017 reported a prevalence of asthma in CF o...
Souza, Elaine Cristina Caon de Pizzichini, Marcia Margaret Menezes Dias, Mirella Cunha, Maíra Junkes Matte, Darlan Lauricio Karloh, Manuela Maurici, Rosemeri Pizzichini, Emilio
ABSTRACT Objective: To estimate the prevalence of respiratory symptoms and asthma, according to body mass index (BMI), as well as to evaluate factors associated with physician-diagnosed asthma, in individuals ≥ 40 years of age. Methods: This was a population-based cross-sectional study conducted in Florianópolis, Brazil, with probability sampling. ...
Hoon Han, Chang Min Lee, Sun Ho Chung, Jae
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Objectives: As the numbers of adolescents with asthma are increasing, appropriate recognition of the importance of body weight is necessary. This study explored body weight misconceptions and related factors in adolescent asthma patients. Methods: Web-based self-reported data from the Korean Youth Risk Behavior Web-Based Survey of 60,974 physician-...
