Suzuki, Yuzo Aono, Yuya Akiyama, Norimichi Horiike, Yasuoki Naoi, Hyogo Horiguchi, Ryo Shibata, Kiyoshi Hozumi, Hironao Karayama, Masato Furuhashi, Kazuki
...
Published in
Autophagy
Obesity is a common comorbidity in patients with asthma, and obese asthma patients present the most refractory phenotype among patients with severe asthma. Similar to the observations in non-obese asthma patients, clinical studies have revealed heterogeneity in obese asthma patients, including the occurrences of T helper (Th)2-high and Th2-low phen...
Mullol, Joaquim Maldonado, Miguel Castillo, José A Miguel-Blanco, Celia Dávila, Ignacio Domínguez-Ortega, Javier Blanco-Aparicio, Marina
Published in
The journal of allergy and clinical immunology. In practice
The clinical approach to upper and lower respiratory diseases from a joint perspective, known as united airways disease (UAD), is challenging for health care professionals owing to a paucity of specific studies. This study reviews recent scientific evidence on the management of asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) from a UAD...
Sun, Fengfei Liang, Yingjian Lin, Minmin Tan, Cuiyan Chen, Meizhu Tu, Changli Shi, Honglei Li, Yanlei Yu, Jinyan Liu, Jing
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Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
There is a lack of information about regulatory T cells (Tregs) and inflammatory phenotypes in patients with asthma. In this study, we aimed to compare the characteristics of Tregs in patients with eosinophilic asthma. Forty healthy and 120 stable asthmatic patients were recruited. Sputum and airway inflammatory phenotypes were assessed, and all pa...
Jin, Yihan Song, Jie Xu, Fang Zhang, Di He, Jinfang Zheng, Jiakun Zhang, Yanan Li, Jintong Guo, Yikun Xu, Mengjiao
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Published in
Sleep & breathing = Schlaf & Atmung
Many studies have shown that chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is associated with asthma. The purpose of this meta-analysis was to evaluate the role of serum YKL-40 in the diagnosis and differential diagnosis of asthma, severity grading, and determination of disease state. The PubMed, Ovid, and Cochrane databases were searc...
Guilleminault, Laurent Conde, Eva Reber, Laurent L
Published in
Pharmacology & therapeutics
Asthma is the most common chronic lung disease, affecting more than 250 million people worldwide. The heterogeneity of asthma phenotypes represents a challenge for adequate assessment and treatment of the disease. However, approximately 50% of asthma patients present with chronic type 2 inflammation initiated by alarmins, such as IL-33 and thymic s...
Coutinho, Maria T Sears, Clara G Noga, Rebecca McQuaid, Elizabeth L Kopel, Sheryl J Powers, Kate E Koinis-Mitchell, Daphne
Published in
Journal of child health care : for professionals working with children in the hospital and community
Asthma symptoms impact children's sleep quality. However, it is unclear how families' daily management of their child's asthma is associated with sleep quality. We examine associations between family asthma management components and sleep duration and quality for urban children (ages 7-9 years). Additionally, we examine these associations by racial...
Kisiel, Marta A Berglund, Charlotte Janson, Christer Hasselgren, Mikael Montgomery, Scott Nager, Anna Sandelowsky, Hanna Ställberg, Björn Sundh, Josefin Lisspers, Karin
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Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
The aim was to investigate if menstruation and use of exogenous sex hormones influence self-reported asthma related quality of life (QoL) and asthma control. The study is based on two asthma cohorts randomly selected in primary and secondary care. A total of 622 female patients 18-65 years were included and classified as premenopausal ≤ 46 years (n...
D'Angelo, Christina Jelalian, Elissa Dunsiger, Shira Noga, Rebecca Kopel, Sheryl J Boergers, Julie Mitchell, Katherine Powers, Kate Koinis-Mitchell, Daphne
Published in
Journal of clinical psychology in medical settings
The present study examined associations between sleep and physical activity among a diverse sample of 97 urban children (ages 7-9) with persistent asthma. Differences in associations were evaluated by race/ethnicity and weight status. The extent to which sleep moderated the association between lung function and physical activity was also evaluated....
Quint, Jennifer K Arnetorp, Sofie Kocks, Janwillem W H Kupczyk, Maciej Nuevo, Javier Plaza, Vicente Cabrera, Claudia Raherison-Semjen, Chantal Walker, Brandie Penz, Erika
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Published in
The journal of allergy and clinical immunology. In practice
Expert national/global asthma management recommendations raise the issue whether a safe threshold of short-acting beta-2 agonist (SABA) use without concomitant inhaled corticosteroids (ICS) exists. To examine SABA and maintenance therapy associations with severe asthma exacerbations across North America and Europe. Observational analyses of 10 SABa...
Averell, Carlyne M Laliberté, François Germain, Guillaume Duh, Mei Sheng Lima, Robson Mahendran, Malena Slade, David J
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Treatment with fluticasone furoate/vilanterol (FF/VI), an inhaled corticosteroid/long-acting β2-agonist therapy, reduces the risk of severe asthma exacerbations and improves lung function and symptom control in patients with asthma. However, real-world data remain limited among asthma patients in the United States (US). This retrospective cohort st...
