Jia, Kaixuan Zhang, Xiaoling Meng, Yijiang Liu, Shuqi Liu, Xiaoqing Yang, Taixin Wen, Chunxiu Liu, Lingdi Ge, Shujun
Published in
Journal of Plant Research
Aster tataricus (L.) is an important medicinal plant in China. Its roots are rich in flavonoids, the main medicinal components. However, the molecular basis of flavonoid biosynthesis in the roots of A. tataricus remains unclear. In this study, the content of total flavonoid of A. tataricus roots at different developmental stages was measured first,...
Chen, Ting Yang, Peng Chen, Hai-Jun Huang, Bin
Published in
Natural product research
A new biflavonoids, (2R,2''R)-7-O-methyl-2,3,2'',3''-tetrahydrorobustaflavone (1), along with five known flavonoids (2-6) were isolated from the MeOH extract of Aster tataricus. Among them, compounds 1-2 were the C-3'-C-6'' type biflavonoids obtained from the genus Aster for the first time. The structures and absolute configurations of compound 1 w...
Song, Yi Wu, Qian Jiang, Huojun Hu, Aihao Xu, Lingqi Tan, Caiping Zhang, Biao Yu, Rongming Qiu, Yizhen Wang, Xin
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Published in
Frontiers in Pharmacology
Purpose: The purpose of the present study was to estimate the effect of shionone (SHI) on sepsis-induced acute lung injury (ALI). Methods: The cecal ligation and puncture (CLP) surgery was performed to induce sepsis in mice. Pulmonary hematoxylin and eosin staining, the wet/dry ratio, myeloperoxidase (MPO) activity, and the survival rate were detec...
Yang, Dongyue Wang, Songrui Huang, Xuhua Ma, Wenjuan Xue, Zixiang Zhao, Lulu Ouyang, Huizi He, Jun
Published in
Journal of separation science
A sensitive ultra-high-performance liquid chromatography-tandem mass spectrometry method was developed and validated to clarify pharmacokinetic properties of 15 compounds (quercetin, isorhamnetin, chlorogenic acid, isoquercitrin, caffeic acid, scopoletin, 7-hydroxycoumarin, shionone, ferulic acid, kaempferol-7-O-β-d-glucopyranoside, methyl caffeate...
Wu, Hao Chen, Yijun Huang, Beibei Yu, Yingting Zhao, Shujun Liu, Jie Jia, Zhixin Xiao, Hongbin
Published in
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
The dried root and rhizome of Aster tataricus (RA), is a traditional Chinese medicine has been used for more than 2000 years with the function of antitussive, expectorant and antiasthmatic. Ancient books and modern pharmacological researches demonstrated that RA may have the function of moistening intestines and relieving constipation, but there wa...
jang, hyun jae kim, y h yang, s y
Aster tataricus L.f. is a traditional Eastern Asian herbal medicine used for the relief of cough-related illnesses. In this study, 32 known compounds and two novel monoterpene glycosides were isolated from the roots of A. tataricus. With the aid of reported data, elucidation of the root-extract components was carried out using a multitude of spectr...
Su, Xiang Dong Jang, Hyun-Jae Li, Hong Xu Kim, Young Ho Yang, Seo Young
Published in
Bioorganic chemistry
Aster tataricus L.f. is a traditional Eastern Asian herbal medicine used for the relief of cough-related illnesses. In this study, 32 known compounds and two novel monoterpene glycosides were isolated from the roots of A. tataricus. With the aid of reported data, elucidation of the root-extract components was carried out using a multitude of spectr...
Schafhauser, T. Jahn, L. Kirchner, N. Kulik, A. Flor, L. Lang, A. Caradec, T. Fewer, D. P. Sivonen, K. Van Berkel, W. J. H.
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peer reviewed / Medicinal plants are a prolific source of natural products with remarkable chemical and biological properties, many of which have considerable remedial benefits. Numerous medicinal plants are suffering from wildcrafting, and thus biotechnological production processes of their natural products are urgently needed. The plant Aster tat...
Wang, Rui Xiao, Sha Niu, Zhongying
Background: Oral squamous carcinoma is a head and neck cancer, which is one of the types of malignant cancers. Present study evaluates the anticancer activity of Aster tataricus (AT) on SCC-9 human oral squamous carcinoma. Materials and Methods: Ethanol extract of AT was prepared by a standard procedure of maceration. AT extract was used in differe...
Zhao, Dong-Xia Hu, Bing-Qiang Zhang, Mian Zhang, Chao-Feng Xu, Xiang-Hong
Published in
Journal of separation science
We established a qualitative method to analyze the main chemical compositions of the root of Aster tataricus. Most of the peaks were separated on a C(18) column packed with 5.0 μm particles, and 28 compounds were identified, including 11 chlorogenic acids, ten astins/asterinins, and seven astersaponins, four of which were reported for the first tim...
