Liu, Fei Feng, Xiaoreng Xiao, Yang Xiang, Jie Chen, Keyu Deng, Yihang Lv, Jiaxin Chen, Bin
Published in
BMC Musculoskeletal Disorders
BackgroundRecently, the infra-acetabular screw has been proposed for use in treatment of acetabular fractures as a part of a periacetabular fixation frame. Biomechanical studies have shown that an additional infra-acetabular screw placement can enhance the fixation strength of acetabular fracture internal fixation. Currently, the reported exit poin...
Ye, Dingwei Liu, Jiyan Zhou, Aiping Zou, Qing Li, Hanzhong Fu, Cheng Hu, Hailong Huang, Jian Zhu, Shaoxing Jin, Jie
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Published in
Cancer science
Tislelizumab, an anti-programmed death protein-1 (PD-1) monoclonal antibody, was engineered to minimize binding to the FcγR on macrophages to abrogate antibody-dependent phagocytosis, a mechanism of T-cell clearance and potential resistance to anti-PD-1 therapy. This single-arm phase 2 trial (NCT04004221/CTR20170071) assessed the safety, tolerabili...
Zou, Dehua Yin, Jingwen Ye, Zhonglv Zeng, Qiaoli Tian, Chuan Wang, Yajun Chen, Qikang Chen, Riling
Published in
Frontiers in Genetics
Background: miR-146a has been demonstrated to be involved in normal hematopoiesis and the pathogenesis of many hematological malignancies by inhibiting the expression of its targets. Rs2910164(G>C) may modify the expression of the miR-146a gene, which might influence an individual's predisposition to childhood acute lymphoblastic leukemia (ALL). Ho...
Charng, Jiun-Ran Chen, Alvin Chao-Yu Chan, Yi-Shen Hsu, Kuo Yao Wu, Chen-Te
Published in
Journal of Orthopaedic Surgery and Research
BackgroundIn cases of Oxford unicompartmental knee arthroplasty (UKA), an increase in anteroposterior and medial-lateral length is usually disproportional when comparing AA and A-sized tibial components. Asynchronous increments may cause tibial keel impingement leading to complications.MethodsRadiographic measurements were performed in five patient...
Pati, Abhijit Mahto, Harishankar Padhi, Sunali Panda, Aditya K
Published in
Clinica chimica acta; international journal of clinical chemistry
Severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) is believed to have emerged from Wuhan, China, and spreads over 215 countries worldwide. The spike protein of SARS-CoV-2 binds to angiotensin-converting enzyme-2 (ACE-2) receptors and enter the host cells. Several reports have been highlighted the importance of ACE-2 on the pathogenesis ...
Chaemsaithong, P Sahota, D Pooh, R K Zheng, M Ma, R Chaiyasit, N Koide, K Shaw, S W Seshadri, S Choolani, M
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Published in
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
To (i) evaluate the applicability of the European-derived biomarker multiples of the median (MoM) formulae for risk assessment of preterm pre-eclampsia (PE) in seven Asian populations, spanning the east, southeast and south regions of the continent, (ii) perform quality-assurance (QA) assessment of the biomarker measurements and (iii) establish cri...
Loo, Guo Hou Rajan, Reynu Deva Tata, Mahadevan Ritza Kosai, Nik
Published in
Annals of medicine and surgery (2012)
Gastrooesophageal reflux disease (GERD) is a spectrum of symptoms arising from the laxity of the cardio-oesophageal junction. Anti-reflux surgery is reserved for patients with refractory GERD. Anterior partial fundoplication (Dor) is a regularly performed anti-reflux surgery in Malaysia. We intend to determine the improvement in disease-specific qu...
Park, Ji Hyun Park, Sunny Choi, Soo An
Published in
BMC Musculoskeletal Disorders
BackgroundWith increasing number of patients undergoing spine surgery, the spinal epidural hemorrhage (SEH) has become a growing concern. However, current studies on SEH rely on case reports or observations from a single center. Our study attempted to demonstrate the incidence rate and risk factors of SEH using a national dataset.MethodsA total of ...
Cao, Xuguang Huang, Mingtao Zhu, Meng Fang, Rui Ma, Zijian Jiang, Tao Dai, Juncheng Ma, Hongxia Jin, Guangfu Shen, Hongbing
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Published in
Cancer medicine
Associations between telomere length and cancer risk have been investigated in many epidemiological studies, but the results are controversial. These associations may be biased by reverse causation or confounded by environmental exposures. To avoid potential biases, we used Mendelian randomization method to evaluate whether TL is the causal risk fa...
Kam, Michelle L.W. Li, Hui Hua Tan, Yi Hern Low, Su Ying
Published in
Respiration
Background: The ILD-GAP model was developed and validated in a Western cohort to predict 1-, 2- and 3-year mortality in chronic interstitial lung disease (ILD). Objectives: We aimed to validate the ILD-GAP model and identify predictors of mortality to derive a nomogram to predict mortality in our local Asian population. Methods: Characteristics of ...
