Lim, Eric Ta Ruiz, Carmen Lyons, Oliver T Laing, Andrew Khanafer, Adib
Published in
Vascular
The presence of a mechanical aortic valve has been a contraindication to the use of an arch branch aortic endograft due to the risk of damaging the valve, resulting in acute aortic regurgitation, or a trapped endograft. We present a 67-year-old woman, with a background of Marfan's syndrome and a previous Bentall's procedure, who presented with a sy...
Williams, Helen; Simmonds, Steven; 119637; Bond, Andrew; Somos, Alexandros; Li, Ze; Forbes, Tessa; Bianco, Rosaria; Dugdale, Celyn; Brown, Zoe; Rice, Helen;
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BACKGROUND AND AIMS: CCN4/WISP-1 regulates various cell behaviours that contribute to atherosclerosis progression, including cell adhesion, migration, proliferation and survival. We therefore hypothesised that CCN4 regulates the development and progression of atherosclerotic plaques. METHODS: We used a high fat fed ApoE-/- mouse model to study athe...
Karaś, Agnieszka Bar, Anna Pandian, Kanchana Jasztal, Agnieszka Kuryłowicz, Zuzanna Kutryb-Zając, Barbara Buczek, Elżbieta Rocchetti, Stefano Mohaissen, Tasnim Jędrzejewska, Agata
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Published in
GeroScience
Vascular ageing is associated with increased arterial stiffness and cardiovascular mortality that might be linked to altered vascular energy metabolism. The aim of this study was to establish a Seahorse XFe96 Analyzer-based methodology for the reliable, functional assessment of mitochondrial respiration and glycolysis in single murine aortic rings ...
Yeerella, Ram Cai, Shengqiang
Aortic dissection, a critical cardiovascular condition with life-threatening implications, is distinguished by the development of a tear and its propagation within the aortic wall. A thorough understanding of the initiation and progression of these tears, or cracks, is essential for accurate diagnosis and effective treatment. This paper undertakes ...
Ichikawa, Keishi Wang, Rui McClelland, Robyn L Manubolu, Venkat S Susarla, Shriraj Lee, Duo Pourafkari, Leili Fazlalizadeh, Hooman Bitar, Jairo Aldana Robin, Rick
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This study compared the prognostic value of quantified thoracic artery calcium (TAC) including aortic arch on chest CT and coronary artery calcium (CAC) score on ECG-gated cardiac CT.MethodsA total of 2412 participants who underwent both chest CT and ECG-gated cardiac CT at the same period were included in the Multi-Ethnic Study of Atherosclerosis ...
Donthula, Rakesh Li, Wen Duvvada, Archita Dyer, Dan Uppu, Santosh C
Published in
Research square
Normative values for intracardiac and extracardiac vascular structures help in understanding normal growth and changes over time in children; this normative data are not currently available for ECG-gated Computed Tomography Angiography (CTA). We sought to establish ECG-gated CTA derived normative values for the aortic root, aorta and aortic arch in...
Moulakakis, Konstantinos G Lazaris, Andreas M Georgiadis, George S Kakkos, Stavros Papavasileiou, Vasileios G Antonopoulos, Constantine N Papapetrou, Anastasios Katsikas, Vasilios Klonaris, Chris Geroulakos, George
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Published in
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Late rupture after endovascular aortic aneurysm repair (EVAR) for an abdominal aortic aneurysm (AAA) is an increasing complication associated with a high mortality rate. This study aimed to analyse the causes and outcomes in patients with AAA rupture after EVAR. A multi-institutional Greek study of late ruptures after EVAR between 2008 - 2022 was p...
Berlot, Ashley A Fu, Xueyan Shea, M Kyla Tracy, Russell Budoff, Matthew Kim, Ryung S Naveed, Mahim Booth, Sarah L Kizer, Jorge R Bortnick, Anna E
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Published in
Atherosclerosis
Matrix Gla protein (MGP) is an inhibitor of calcification that requires carboxylation by vitamin K for activity. The inactive form of MGP, dephosphorylated-uncarboxylated matrix Gla protein (dp-ucMGP), has been associated with increased calcification. However, it is not known whether there is a longitudinal relationship between dephosphorylated-unc...
Ramachandra, Abhay B Cavinato, Cristina Humphrey, Jay D
Published in
Annals of biomedical engineering
The greater thoracic vessels are central to a well-functioning circulatory system and are often targeted in congenital heart surgeries, yet the structure and function of these vessels have not been well studied. Here we use consistent methods to quantify and compare microstructural features and biaxial biomechanical properties of the following six ...
Lim, Eric T A Kim, Hannah S Khanafer, Adib
Published in
European journal of trauma and emergency surgery : official publication of the European Trauma Society
Blunt thoracic aortic injury (BTAI) is associated with a high mortality and is the second most common cause of death from trauma. The approach to major trauma, imaging technology and advancement in endovascular therapy have revolutionised the management of BTAI. Endovascular therapy has now become the gold standard technique replacing surgery with ...