Donner, Nina C Davies, Sofia M Fitz, Stephanie D Kienzle, Drake M Shekhar, Anantha Lowry, Christopher A
Published in
Progress in neuro-psychopharmacology & biological psychiatry
The bed nucleus of the stria terminalis (BNST) is a nodal structure in neural circuits controlling anxiety-related defensive behavioral responses. It contains neurons expressing the stress- and anxiety-related neuropeptide corticotropin-releasing hormone (Crh) as well as Crh receptors. Repeated daily subthreshold activation of Crh receptors in the ...
Sohanpal, Ratna Pinnock, Hilary Steed, Liz Heslop Marshall, Karen Chan, Claire Kelly, Moira Priebe, Stefan Roberts, C. Michael Singh, Sally Smuk, Melanie
...
Published in
Trials
BackgroundPeople with chronic obstructive pulmonary disease (COPD) are at increased risk of depression and anxiety, which greatly reduces their quality of life and is associated with worse outcomes; but these psychological co-morbidities are under-recognised and undertreated in COPD patients. Pulmonary rehabilitation (PR) improves mood for up to 6 ...
Ibrahim, Lamis Abouhendy, Wail Raafat, Nelly Fouad, Amira Ahmed
Published in
Middle East Current Psychiatry
BackgroundHigh rates of history of childhood attention deficit hyperactivity disorder (ADHD) symptoms have been found in obsessive-compulsive disorder (OCD) adults. Both, when comorbid, cause the clinical course to be unfavorable, more susceptibility to substance use, and a bad response to treatment. We planned to assess the impact of childhood ADH...
Frances, Sarah Shawyer, Frances Cayoun, Bruno Enticott, Joanne Meadows, Graham
Published in
BMC Psychiatry
BackgroundEffective transdiagnostic treatments for patients presenting with principal or comorbid symptoms of anxiety and depression enable more efficient provision of mental health care and may be particularly suitable for the varied population seen in primary healthcare settings. Mindfulness-integrated cognitive behavior therapy (MiCBT) is a tran...
Won, Soonmi Park, Keebum Lim, Hyoungsub Lee, Sung Joong
Published in
Behavioral and Brain Functions
BackgroundA sex-difference in susceptibility to chronic pain is well-known. Although recent studies have begun to reveal the sex-dependent mechanisms of nerve injury-induced pain sensitization, sex differences in the affective and cognitive brain dysfunctions associated with chronic pain have not been investigated. Therefore, we tested whether chro...
Falk, Eduard Schlieper, Daniel van Caster, Patrick Lutterbeck, Matthias J. Schwartz, Jacqueline Cordes, Joachim Grau, Ina Kienbaum, Peter Neukirchen, Martin
Published in
BMC Palliative Care
BackgroundPatients in palliative care need rapid-acting pharmacological options for psychological distress. N-methyl-D-aspartate antagonist ketamine is known to have a fast onset of anti-depressant and anxiolytic action. Its S-enantiomer S-ketamine (or esketamine) is an analgesic used as a routine treatment for refractory pain as an intravenous inf...
Janssen, Katherine Rosielle, Drew Wang, Qi Kim, Hyun Joo
Published in
Respiratory Research
BackgroundIdiopathic pulmonary fibrosis (IPF) is a fatal disease that results in poor quality of life due to progressive respiratory symptoms, anxiety, and depression. Palliative care improves quality of life and survival in other progressive diseases. No randomized controlled trials have investigated the impact of palliative care on quality of lif...
LaFrance, Emily M. Stueber, Amanda Glodosky, Nicholas C. Mauzay, Dakota Cuttler, Carrie
Published in
Journal of Cannabis Research
BackgroundTrends toward legalizing cannabis may increase experimentation with the drug among less experienced users with limited knowledge of possible adverse reactions. This study explores the prevalence, frequency, and levels of distress produced by various acute adverse reactions to cannabis, as well as predictors of these reactions.MethodsThe A...
Aleo Luján, Esther Lopez-Picado, Amanda Rivas, Ana Joyanes Abancens, Belén Rodríguez Rojo, Marina Laura Fernández García, Patricia Soto Beauregard, Carmen Rodríguez Alarcón, Jaime González Perrino, Carlos San Pedro de Urquiza, Borja
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Published in
Trials
BackgroundSurgery can generate significant stress and anxiety in up to 70% of the paediatric population. There are several pharmacological and non-pharmacological strategies to reduce pre-operative anxiety in children, however, they have several side effects and the available information about them is contradictory. The role of clowns and hydroxyzi...
Ramos, Daniela Figueiredo Magalhães, Joana Santos, Paulo Vale, Jorge Santos, Maria Inês
ABSTRACT Objective: To report a case of recurrent isolated sleep paralysis (RISP), a benign parasomnia with worrisome and frightening sleep paralysis episodes. Case description: We describe a case of RISP in a sixteen-year-old girl who seeks medical attention for anxiety symptoms. The sleep paralysis and associated auditory and tactile hallucinatio...
