Lundstrom, Kenneth Hromić-Jahjefendić, Altijana Bilajac, Esma Aljabali, Alaa A A Baralić, Katarina Sabri, Nagwa A Shehata, Eslam M Raslan, Mohamed Raslan, Sara A Ferreira, Ana Cláudia B H
The COVID-19 pandemic has triggered intensive research and development of drugs and vaccines against SARS-CoV-2 during the last two years. The major success was especially observed with development of vaccines based on viral vectors, nucleic acids and whole viral particles have received emergent authorization leading to global mass vaccinations. Al...
Das, Bihter Kutsal, Mucahit Das, Resul
Chemometrics and intelligent laboratory systems : an international journal sponsored by the Chemometrics Society
Although the coronavirus epidemic spread rapidly with the Omicron variant, it lost its lethality rate with the effect of vaccine and immunity. The hospitalization and intense demand decreased. However, there is no definite information about when this disease will end or how dangerous the different variants could be. In addition, it is not possible ...
Choudhary, Neha Singh, Vikram
The novel coronavirus disease (COVID-19), which emerged in Wuhan, China, is continuously spreading worldwide, creating a huge burden on public health and economy. Ayurveda, the oldest healing schema of Traditional Indian Medicinal (TIM) system, is considered as a promising CAM therapy to combat various diseases/ disorders. To explore the regulatory...
Trawiński, Jakub Wroński, Michał Skibiński, Robert
Journal of environmental management
In this study photochemical transformation of the antiretroviral pharmaceutical maraviroc under the simulated UV-Vis radiation was presented. The drug was shown to be extremely photo-resistant, with a half-life over 250 h, which is particularly significant, considering its presence in the aquatic environments. Addition of the natural river water ma...
Saraswat, Juhi Riaz, Ufana Patel, Rajan
Journal of molecular liquids
The pandemic due to COVID-19 caused by SARS-CoV-2 has led to the recorded deaths worldwide and is still a matter of concern for scientists to find an effective counteragent. The combination therapy is always been a successful attempt in treating various threatful diseases. Recently, Ionic liquids (ILs) are known for their antiviral activity. Fascin...
Mlozi, Stephano Hanolo
COVID-19; Phytochemicals; Medicinal plants; Antiviral drugs; Phytochemical screening.
Cappelli, Francesca Longoni, Orietta Rigato, Jacopo Rusconi, Michele Sala, Alberto Fochi, Igor Palumbo, Maria Teresa Polesello, Stefano Roscioli, Claudio Salerno, Franco
The Science of the total environment
During the first period of the SARS-CoV-2 pandemic, the lack of specific therapeutic treatments led to the provisional use of a number of drugs, with a continuous review of health protocols when new scientific evidence emerged. The management of this emergency sanitary situation could not take care of the possible indirect adverse effects on the en...
Coronavirus Drug Discovery
Coronavirus disease 2019 (COVID-19) is a disease caused by the novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The name coronavirus was derived from their crown-like spikes that exist on their exterior. Coronaviruses have been classified into four main subcategories, namely, alpha, beta, gamma, and delta coron...
Czech, Bożena Krzyszczak, Agnieszka Boguszewska-Czubara, Anna Opielak, Grzegorz Jośko, Izabela Hojamberdiev, Mirabbos
The Science of the total environment
In coronavirus disease 2019 (COVID-19), among many protocols, lopinavir and ritonavir in individual or combined forms with other drugs have been used, causing an increase in the concentration of antiviral drugs in the wastewater and hospital effluents. In conventional wastewater treatment plants, the removal efficiency of various antiviral drugs is...
Roncato, Rossana Angelini, Jacopo Pani, Arianna Talotta, Rossella
Biochimica et biophysica acta. Molecular and cell biology of lipids
Lipid rafts are nanoscopic compartments of cell membranes that serve a variety of biological functions. They play a crucial role in viral infections, as enveloped viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can exploit rafts to enter or quit target cells. On the other hand, lipid rafts contribute to the formation of...