Datta, Manjari Rajeev, Ashwin Chattopadhyay, Indranil
Published in
Biotechnology & genetic engineering reviews
Antimicrobial peptide (AMP), also called host defense peptide, is a part of the innate immune system in eukaryotic organisms. AMPs are also produced by prokaryotes in response to stressful conditions and environmental changes. They have a broad spectrum of activity against both Gram positive and Gram negative bacteria. They are also effective again...
Summer, Kate Liu, Lei Guo, Qi Barkla, Bronwyn Benkendorff, Kirsten
Published in
Marine biotechnology (New York, N.Y.)
Pneumococcal infections caused by Streptococcus pneumoniae are a leading cause of morbidity and mortality globally, particularly among children. The ability of S. pneumoniae to form enduring biofilms makes treatment inherently difficult, and options are further limited by emerging antibiotic resistance. The discovery of new antibiotics, particularl...
Boukherissa, Amira
Legume plants under nitrogen deficiency can enter a symbiotic interaction with N₂-fixing soil bacteria called rhizobia. In five legume clades, an exploitive strategy called Terminal Bacteroid Differentiation (TBD) has evolved in which rhizobia undergo extreme differentiation. Terminally differentiated bacteria are larger, polyploid, have a permeabi...
Laïb, Allan
Cette thèse explore le potentiel des champignons comme source de composés bioactifs, particulièrement dans le contexte de la recherche médicale et pharmaceutique. Les champignons, grâce à leur diversité chimique, offrent une multitude de métabolites secondaires aux propriétés thérapeutiques variées, incluant des activités antibactériennes, anticanc...
Xia, Jing Ge, Chaorong Yao, Huaiying
Published in
Environmental research
The utilization of antibiotics increases the prevalence of antibiotic resistance genes (ARGs) in various matrices and poses the potential risk of ARG transmission, garnering global attention. Antimicrobial peptides (AMPs) represent a promising novel category of antimicrobials that may address the urgent issue of antibiotic resistance. Here, a zebra...
Farzi, Nastaran Oloomi, Mana Bahramali, Golnaz Siadat, Seyed Davar Bouzari, Saeid
Published in
Probiotics and antimicrobial proteins
Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii have emerged as major clinical threats owing to the increasing prevalence of ventilator-associated pneumonia caused by multidrug-resistant or extensively drug-resistant strains. The present study aimed to assess the antibacterial effects and efficacy of LL-37 fragment GF-17D...
Fahmy, Leila Generalovic, Tomas Ali, Youssif M Seilly, David Sivanesan, Kesavan Kalmar, Lajos Pipan, Miha Christie, Graham Grant, Andrew J
BACKGROUND: The world faces a major infectious disease challenge. Interest in the discovery, design, or development of antimicrobial peptides (AMPs) as an alternative approach for the treatment of bacterial infections has increased. Insects are a good source of AMPs which are the main effector molecules of their innate immune system. Black Soldier ...
Chen, Chen Shi, Jingru Wang, Dejuan Kong, Pan Wang, Zhiqiang Liu, Yuan
Published in
Critical reviews in microbiology
The widespread antimicrobial resistance (AMR) calls for the development of new antimicrobial strategies. Antibiotic adjuvant rescues antibiotic activity and increases the life span of the antibiotics, representing a more productive, timely, and cost-effective strategy in fighting drug-resistant pathogens. Antimicrobial peptides (AMPs) from syntheti...
Wiita, Elizabeth
Molecular self-assembly is a key process evolved by nature, through which functional materials are generated. Among these processes, protein self-assembly into hierarchical structures provides an important avenue for the development of materials with a wide range of biomedical applications. Self-assembly exploits the formation of strong, non-covale...
Feng, Junxi Sun, Mengtao Liu, Cong Zhang, Weiwei Xu, Changmou Wang, Jieqiong Wang, Guangshun Wan, Shibiao
Published in
bioRxiv : the preprint server for biology
It is projected that 10 million deaths could be attributed to drug-resistant bacteria infections in 2050. To address this concern, identifying new-generation antibiotics is an effective way. Antimicrobial peptides (AMPs), a class of innate immune effectors, have received significant attention for their capacity to eliminate drug-resistant pathogens...
