Published in Mycological Progress
As part of a survey of foliar endophytes of conifers in the Acadian forest, we isolated a strain of Lachnellula calyciformis from a healthy Picea rubens needle. From this fungus, the new natural products deoxylachnellulone (3) and lachnelluloic acid B (5), and the known metabolite lachnellulone (1), were isolated and structurally characterized. Iso...
Published in Egyptian Journal of Biological Pest Control
BackgroundFungi are one of the microorganisms that cause most damage to fruits worldwide, affecting their quality and consumption. Chemical controls with pesticides are used to diminish postharvest losses of fruits. However, biological control with microorganisms or natural compounds is an increasing alternative to protect fruits and vegetables. In...
Published in BMC Complementary Medicine and Therapies
BackgroundMedicinal plants have been used in the treatment of various ailments in most developing countries. Oral infections are the most prevalent diseases in man. The Rhus family has been found to have antimicrobial, antimalarial, and anti-inflammatory properties. Few studies have been done on Rhus vulgaris Meikle. A study was conducted to determ...
Published in Applied Microbiology and Biotechnology
Candida infections are a significant source of patient morbidity and mortality. Candida albicans is the most common pathogen causing Candida infections. Candida auris is a newly described pathogen that is associated with multi-drug-resistant candidiasis and candidaemia in humans. The antifungal effects of various essential oils and plant compounds ...
Published in BMC Microbiology
BackgroundAcetic acid has been used to clean and disinfect surfaces in the household for many decades. The antimicrobial efficacy of cleaning procedures can be considered particularly important for young, old, pregnant, immunocompromised people, but may also concern other groups, particularly with regards to the COVID-19 pandemics.This study aimed ...
Published in Bioorganic chemistry
2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonyl chloride 1 was prepared via reaction of o-phenylene diamine with oxalic acid followed by chlorosulfonation with excess chlorosulfonic acid. A series of new sulfonylquinoxaline derivatives 2-6 were obtained upon reacting compound 1 with different types of amines. 2,3-Dichloro-6-morpholinosulfonylqui...
Published in Network Modeling Analysis in Health Informatics and Bioinformatics
This paper explores the confluence of genetic algorithm-multiple linear regression (GA-MLR) based quantitative structure–activity relationship (QSAR) modeling and molecular docking simulation studies relevant to the novel and effective triazole derivatives as NMT inhibitors in an attempt to develop superior antifungal activity coupled with less sus...
Published in Chemistry and physics of lipids
Ketoconazole (KZ) is a broad-spectrum imidazole antifungal agent, used in opportunistic systemic fungal infection treatment. Gastrointestinal absorption of this drug is variable and depends on the pH of the absorption site. The objective of the investigation was the development and characterization of (KZ) loaded lipid nanoformulations (KZ-LNFs) su...
Published in Biotechnology Reports
This research aimed to explore the eco-friendly green synthesis of copper nanoparticles (CuNPs) using Celastrus paniculatus leaves extract. Primarily, the biosynthesized CuNPs characterized by UV–vis spectroscopy showed an absorption peak at 269 nm. Further, The SEM and TEM studies revealed the spherical shape of particles with size ranged between ...
Published in Journal of Food Science and Technology
The objective of this study was to develop antifungal fragrant brown rice using the vapour phase of Michelia alba oil and to understand the effects of fragrant brown rice on consumer reactions using an electroencephalography (EEG) technique. The effect of M. alba oil vapour (300–900 µL/L) on the growth of moulds was studied in brown rice. Then, opt...
