Moore, Kathryn M. Suthar, Mehul S.
Published in
Biochemical and Biophysical Research Communications
The COVID-19 pandemic resulting from the emergence of the coronavirus SARS-CoV-2 remains a major global health concern. Pregnant individuals are more likely to develop severe COVID-19 and a number of pregnancy complications have been observed in COVID-19 patients. To date, little is known about the impact of COVID-19 on pregnancy. In this review, w...
Zhang, Xiaoyong Lu, Suwen Li, Hui Wang, Yi Lu, Zhen Liu, Zhihong Lai, Qingtao Ji, Yali Huang, Xuan Li, Yongyin
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Published in
Virologica Sinica
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly around the world, posing a major threat to human health and the economy. Currently, long-term data on viral shedding and the serum antibody responses in COVID-19 patients are still limited. Herein, we report the clinical f...
Fu, Richard Y Chen, Alex C Lyle, Meghan J Chen, Chun-Yu Liu, Chao Lien Miao, Carol H
Published in
Cellular immunology
Although protein replacement therapy provides effective treatment for hemophilia A patients, about a third of severe patients develop neutralizing inhibitor antibodies to factor VIII. Adoptive transfer of regulatory T cells (Tregs) has shown promise in treating unwanted immune responses. In previous studies, transferred polyclonal Tregs ameliorated...
Pornanek, Pitukpol Phoemchalard, Chirasak
Published in
Tropical Animal Health and Production
This research investigated the impact of dietary beta-glucan-rich molasses yeast powder (MYP) supplementation on the antibody response to swine fever virus (Titer) and hematology of starter–grower pig. Sixteen cross pigs (30 kg body weight) were equally split into four groups; each group with four replicates and fed four dietary treatments that con...
Weis, Sebastian Scherag, André Baier, Michael Kiehntopf, Michael Kamradt, Thomas Kolanos, Steffi Ankert, Juliane Glöckner, Stefan Makarewicz, Oliwia Hagel, Stefan
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Published in
Clinical Microbiology and Infection
Objectives Due to a substantial proportion of asymptomatic and mild courses, many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections remain unreported. Therefore, assessment of seroprevalence may detect the real burden of disease. We aimed to determine and characterize the rate of SARS-CoV-2 infections and the resulting seropre...
Thompson, Hayley A. Hogan, Alexandra B. Walker, Patrick G.T. White, Michael T. Cunnington, Aubrey J. Ockenhouse, Christian F. Ghani, Azra C.
Published in
Vaccine
Anti-circumsporozoite antibody titres have been established as an essential indicator for evaluating the immunogenicity and protective capacity of the RTS,S/AS01 malaria vaccine. However, a new delayed-fractional dose regime of the vaccine was recently shown to increase vaccine efficacy, from 62.5% (95% CI 29.4–80.1%) under the original dosing sche...
Ohta, Minoru Bannai, Hiroshi Nemoto, Manabu Kambayashi, Yoshinori Tamura, Norihisa Tsujimura, Koji
Published in
Journal of equine veterinary science
An inactivated equine influenza virus (EIV) vaccine and a live equine herpesvirus type 1 (EHV-1) vaccine are usually administered concurrently to Thoroughbred racehorses in Japan. The objective of this study was to evaluate whether concurrent administration of an inactivated EIV vaccine and a live EHV-1 vaccine in Thoroughbred racehorses influences...
Gabriele, Lucia Fragale, Alessandra Romagnoli, Giulia Parlato, Stefania Lapenta, Caterina Santini, Stefano Maria Ozato, Keiko Capone, Imerio
Published in
Cytokine & Growth Factor Reviews
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, induces severe pneumonia mainly in elderly males. Epidemiological data clearly indicate sex-based differences in disease outcomes, with men accounting for about 70 % of deaths, despite similar susceptibility...
Arvey, Aaron Rowe, Michael Legutki, Joseph Barten An, Gang Gollapudi, Anantha Lei, Anna Colston, Bill Putterman, Chaim Smith, David Stiles, Janelle
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Published in
Immunity & Ageing
BackgroundThe immune system undergoes a myriad of changes with age. While it is known that antibody-secreting plasma and long-lived memory B cells change with age, it remains unclear how the binding profile of the circulating antibody repertoire is impacted.ResultsTo understand humoral immunity changes with respect to age, we characterized serum an...
Thompson, H Hogan, A Walker, P White, M Cunnington, A Ockenhouse, C Ghani, A
Anti-circumsporozoite antibody titres have been established as an essential indicator for evaluating the immunogenicity and protective capacity of the RTS,S/AS01 malaria vaccine. However, a new delayed-fractional dose regime of the vaccine was recently shown to increase vaccine efficacy, from 62.5% (95% CI 29.4–80.1%) under the original dosing sche...