de Moraes Neto, Jarbas Emílio Pereira, Felipe Neves, Raquel Leão de Barros, Nilana Meza Tenório Gil, Cristiane Damas Fernandes, Arthur Gustavo Watanabe, Sung Eun Song Meyer, Carsten Helmut Farah, Michel Eid Rodrigues, Eduardo Buchele
...
Published in
International Journal of Retina and Vitreous
BackgroundAnti-angiogenic drugs remain the mainstay therapy for several vascular retinal pathologies. The repurposing of approved anti-angiogenic drugs for use in ophthalmology can increase therapeutic options and reduce costs. The purpose of this study was to investigate the ocular safety profile of intravitreal (IVT) ramucirumab, an approved anti...
Maeda, Yoshiaki Shinohara, Toshiki Minagawa, Nozomi Kobayashi, Tadayuki Koyama, Ryota Shimada, Shingo Tsunetoshi, Yusuke Murayama, Keisuke Hasegawa, Haruka
Published in
Annals of medicine and surgery (2012)
Treatment for acute abdomen during chemotherapy is frequently difficult because of the complicated status of the patients, and there have been only a few case series summarizing the outcomes of emergent surgery during chemotherapy. The aim of this study was to clarify the clinical outcomes of emergency surgery for acute abdomen during chemotherapy ...
Levine, Emily S. Custo Greig, Eugenia Mendonça, Luísa S. M. Gulati, Shilpa Despotovic, Ivana N. Alibhai, A. Yasin Moult, Eric Muakkassa, Nora Quaranta-El Maftouhi, Maddalena El Maftouhi, Adil
...
Published in
International Journal of Retina and Vitreous
BackgroundThe short-term effects of anti-vascular endothelial growth factor (anti-VEGF) treatment on macular neovascularization (MNV) morphology is well described, but long-term studies on morphologic changes and correlation of such changes to the type of MNV have not been conducted. This study aims to determine if different types of MNVs in neovas...
Gnanasekaran, Sivashanth Rogers, Sophie Wickremasinghe, Sanj Sandhu, Sukhpal S.
Published in
BMC Ophthalmology
Clinicians adopt varying strategies for antisepsis with PI, which to this day remains efficient, economical and effective. Clinicians should prudently consider effective PI application, and we thank Koerner and Grzybowski for encouraging debate and raising the profile of this issue.
Tan, Colin S. Lim, Louis W. Ngo, Wei Kiong Pannirselvam, Pandiyan See, Clarence Chee, Wai Kitt Saxena, Nakul
Published in
BMC Ophthalmology
BackgroundTo determine the frequency of persistent disease activity following 3 loading doses of anti- vascular endothelial growth factor (VEGF) agents, and the anatomic and demographic predictors of early persistent disease activity among patients with neovascular age-related macular degeneration (nAMD).MethodsIn a retrospective real-world cohort ...
Stone, Lydia G. Devenport, Adele Stratton, Irene M. Talks, James S.
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology
Purpose To assess the treatment position of all patients who have had an anti-VEGF injection in 2020, prior to the UK lockdown on 23 March. To assess methods of service quality evaluation in setting benchmarks for comparison after the situation stabilized. To consider what proportion could be delayed based on national guidelines and varying vision ...
Finger, Robert P. Daien, Vincent Eldem, Bora M. Talks, James S. Korobelnik, Jean-Francois Mitchell, Paul Sakamoto, Taiji Wong, Tien Yin Pantiri, Krystallia Carrasco, Joao
...
Published in
BMC Ophthalmology
BackgroundSystematically review the evidence describing the impact of anti–vascular endothelial growth factor (anti-VEGF) therapy on neovascular age-related macular degeneration (nAMD) patient outcomes and healthcare resource utilization.MethodsA systematic literature review was completed using Medline and EMBASE for publications prior to July 2018...
Sharma, Shashikant Anandkumar, Manjunath Bhaskar Jain, Sangita Murthy, Hemanth Murlidhar, Naveenam Srinivasa Hirawat, Raj Shri Sudhalkar, Aditya Deka, Amarendra Banker, Alay Parikh, Vatsal
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Published in
Ophthalmology and Therapy
Purpose The REal life assessmENt of safety And effeCTiveness of Razumab 2 (RE-ENACT 2) study evaluated the long-term effectiveness of biosimilar ranibizumab. We present the subgroup analysis of patients with retinal vein occlusion (RVO). Methods Data of patients who received pro re nata (PRN) biosimilar ranibizumab (November 2015 to December 2018, ...
Patel, Nimesh A. Berrocal, Audina M. Murray, Timothy G. Villegas, Victor M.
Published in
American Journal of Ophthalmology Case Reports
• Intravitreal brolucizumab may be used in select pediatric patients with positive outcomes. • Patients with Coats' disease may benefit from the efficacy of intravitreal brolucizumab. • Intravitreal brolucizumab combined with laser photocoagulation can be effective for advanced Coats disease.
Sorour, Osama A. Liu, Keke Mehta, Nihaal Braun, Phillip Gendelman, Isaac Nassar, Elsayed Baumal, Caroline R. Witkin, Andre J. Duker, Jay S. Waheed, Nadia K.
...
Published in
International Journal of Retina and Vitreous
BackgroundTo compare the anatomical and visual outcomes in eyes with persistent diabetic macular edema (DME) after initial anti-VEGF therapy that were retreated continuously with the same anti-VEGF drug versus those that underwent two successive cycles of medication change in anti-VEGF drugs (double anti-VEGF switch).MethodsRetrospective review of ...
