Nam, Bora Koo, Bon San Lee, Tae-Han Shin, Ji-Hui Kim, Jin-Ju Lee, Seunghun Joo, Kyung Bin Kim, Tae-Hwan
Published in
BMC Musculoskeletal Disorders
BackgroundThe purpose of this study was to determine the prevalence of high disease activity as measured using the Ankylosing Spondylitis Disease Activity Score (ASDAS) in ankylosing spondylitis (AS) patients who nonetheless have low Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) scores after anti-tumor necrosis factor (TNF) treatment....
Han, Lei Quan, Renfu Pei, Zhenle Cao, Guoping Hu, Yungen Liu, Jingjing
Published in
Journal of Orthopaedic Surgery and Research
BackgroundTotal hip arthroplasty (THA) for bony ankylosis is technically challenging in patients with ankylosing spondylitis (AS). This study aimed to determine the mid-term results of bilateral synchronous THA for bony ankylosis in patients with AS.MethodsNineteen cases of bony ankylosis in patients with AS who received bilateral synchronous THA w...
Yuce Inel, Tuba Kisa, Pelin Teke Balci, Ali Uslu, Sadettin Arslan, Zumrut Hismi, Burcu Ozturk Ucar, Ulku Arslan, Nur Onen, Fatos Sari, Ismail
...
Published in
Modern rheumatology
Ochronotic arthropathy (OcA) refers to excessive homogentisic acid (HGA) deposition in the musculoskeletal system. Our current understanding of OcA is limited, as there are less than a thousand alkaptonuria (AKU) cases reported in the literature. Herein, we investigated the rheumatological manifestations of OcA in a group of adult AKU patients. Adu...
Mader, Reuven Pappone, Nicola Baraliakos, Xenofon Eshed, Iris Sarzi-Puttini, Piercarlo Atzeni, Fabiola Bieber, Amir Novofastovski, Irina Kiefer, David Verlaan, Jorrit-Jan
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Published in
Current Rheumatology Reports
Purpose of ReviewDiffuse Idiopathic Skeletal Hyperostosis (DISH) is considered a metabolic condition, characterized by new bone formation affecting mainly at entheseal sites. Enthesitis and enthesopathies occur not only in the axial skeleton but also at some peripheral sites, and they resemble to some extent the enthesitis that is a cardinal featur...
Wang, Yu Li, Chunde Liu, Long Qi, Longtao
Published in
BMC Musculoskeletal Disorders
BackgroundTo report a mini-open pedicle subtraction osteotomy (PSO) technique, to summarize the 2-year follow-up results of 25 patients, and to describe a modified operating table which allows the osteotomy to be closed in a more controllable manner.MethodsWe retrospectively reviewed the records of patients with AS who received one-level mini-open ...
da Cruz Lage, Ricardo Marques, Claudia Diniz Lopes Oliveira, Thauana Luiza Resende, Gustavo Gomes Kohem, Charles Lubianca Saad, Carla Gonçalves Ximenes, Antônio Carlos Gonçalves, Célio Roberto Bianchi, Washington Alves de Souza Meirelles, Eduardo
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Published in
Advances in Rheumatology
Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been the basis for the pharmacological treatment of patients with axial spondyloarthritis (axSpA)....
Breban, Maxime Glatigny, Simon Cherqaoui, Bilade Beaufrère, Marie Lauraine, Marc Rincheval-Arnold, Aurore Gaumer, Sébastien Gueńal, Isabelle Araujo, Luiza
Understanding the complex mechanisms underlying a disorder such as spondyloarthritis (SpA) may benefit from studying animal models. Several suitable models have been developed, in particular to investigate the role of genetic factors predisposing to SpA, including HLA-B27, ERAP1, and genes related to the interleukin (IL)-23/IL-17 axis. One of the b...
Citera, Gustavo Bautista-Molano, Wilson Peláez-Ballestas, Ingris Azevedo, Valderilio F. Perich, Risto A. Méndez-Rodríguez, José A. Cutri, Mariel S. Borlenghi, Cecilia E.
Published in
Advances in Rheumatology
Large epidemiologic and clinical estimates of spondyloarthritis (SpA) in Latin America are not available. In this narrative review, our goal was to descriptively summarize the prevalence and features of SpA in Latin America, based on available small studies. A review of peer-reviewed literature identified 41 relevant publications. Of these, 11 (mos...
Lage, Ricardo da Cruz Marques, Claudia Diniz Lopes Oliveira, Thauana Luiza Resende, Gustavo Gomes Kohem, Charles Lubianca Saad, Carla Gonçalves Ximenes, Antônio Carlos Gonçalves, Célio Roberto Bianchi, Washington Alves Meirelles, Eduardo de Souza
...
Abstract Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been the basis for the pharmacological treatment of patients with axial spondyloarthritis...
Liu, Suling Cui, Yang Zhang, Xiao
Published in
Clinical rheumatology
Iguratimod (IGU) is a novel small molecule anti-rheumatic drug with the effect of non-steroidal anti-inflammatory drug and disease-modifying anti-rheumatic drug. IGU has various mechanisms of action, including inhibition of prostaglandin E2, tumor necrosis factor-α (TNF-α), interleukin-17 (IL-17) production, inhibition of macrophage migration inhib...
