Zhao, Sizheng Steven Robertson, Selina Reich, Tzvi Harrison, Nicolas L Moots, Robert J Goodson, Nicola J
Published in
Rheumatology (Oxford, England)
Objectives Comorbidities are common in people with axial spondyloarthritis (axSpA). In this systematic review and meta-analysis, we aimed to: (i) describe the prevalence of commonly reported comorbidities, (ii) compare comorbidities between axSpA and control populations, and (iii) examine the impact of comorbidity burden on axSpA outcomes. Methods ...
Zhou, Zhongwei Chen, Hongmei Ju, Huixiang Sun, Mingzhong Jin, Hao
Published in
Platelets
Correlation between platelet indices and chronic inflammatory arthritis (CIA) remains a moot point today. This meta-analysis aimed to evaluate whether platelet (PLT) count, mean platelet volume (MPV) and platelet distribution width (PDW) associated with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA). A systemat...
Maruiwa, Ryosuke Watanabe, Kota Suzuki, Satoshi Nori, Satoshi Tsuji, Osahiko Nagoshi, Narihito Okada, Eijiro Yagi, Mitsuru Fujita, Nobuyuki Nakamura, Masaya
...
Published in
Neurospine
Chin on chest deformity caused by upper cervical kyphosis associated with ankylosing spondylitis is rare. A 66-year-old woman presented at our institute with chief complaints of difficulty in horizontal gaze and opening her mouth. Cervical radiographs showed a C0–2 angle of 1° on flexion and 7° on extension, and her chin-brow vertical angle was 49°...
Webers, Casper Stolwijk, Carmen Schiepers, Olga Schoonbrood, Thea van Tubergen, Astrid Landewé, Robert van der Heijde, Désirée Boonen, Annelies
Published in
Arthritis Research & Therapy
BackgroundPatients with ankylosing spondylitis (AS) are at increased risk of depression. This increased risk has been hypothesized to be solely secondary due to AS-related symptoms, or additionally due to a common inflammatory pathway. From a clinical perspective, it is important to know whether treatment with tumor necrosis factor alpha inhibitors...
Abrar, Daniel B. Schleich, Christoph Tsiami, Styliani Müller-Lutz, Anja Radke, Karl Ludger Holthausen, Neela Frenken, Miriam Boschheidgen, Matthias Antoch, Gerald Mucke, Johanna
...
Published in
Arthritis Research & Therapy
BackgroundTo compare the glycosaminoglycan (GAG) content of lumbar intervertebral disks (IVDs) of patients with ankylosing spondylitis (AS) and healthy volunteers and to investigate the association of GAG depletion and disease-related clinical and imaging features.MethodsLumbar spines of 50 AS patients (mean age 50 ± 10.5 years) and 30 age-matched ...
Ye, Guiwen Xie, Zhongyu Zeng, Huiqiong Wang, Peng Li, Jinteng Zheng, Guan Wang, Shan Cao, Qian Li, Ming Liu, Wenjie
...
Published in
Cell Death & Disease
Ankylosing spondylitis (AS) is a chronic inflammatory disease possessing a morbid serum microenvironment with enhanced oxidative stress. Long-term exposure to an oxidative environment usually results in cellular senescence alone with cellular dysfunction. Mesenchymal stem cells (MSCs) are a kind of stem cell possessing strong capabilities for immun...
Mantravadi, Santhi George, Michael Brensinger, Colleen Du, Min Baker, Joshua F. Ogdie, Alexis
Published in
BMC Rheumatology
BackgroundTo determine whether initiation of a tumor necrosis factor inhibitor (TNFi) or methotrexate improves hemoglobin A1c in patients with psoriatic arthritis (PsA), rheumatoid arthritis (RA), or ankylosing spondylitis (AS) who also have diabetes mellitus (DM).MethodsA retrospective cohort study was conducted in Optum’s de-identified Clinformat...
Butt, Bilal B. Gagnet, Paul Piche, Joshua Patel, Rakesh Aleem, Ilyas S.
Published in
Journal of Spine Surgery
A number of spinal pathologies result in fusion of the spine, including ankylosing spondylitis, diffuse idiopathic skeletal hyperostosis (DISH), as well as severe degenerative arthropathies. This fusion of spinal elements may result in spinal deformity affecting any region of the spine. Cervicothoracic deformity resulting in chin on chest deformity...
Manica, Santiago Rodrigues Sepriano, Alexandre Pimentel-Santos, Fernando Gouveia, Nélia Barcelos, Anabela Branco, Jaime C. Bernardes, Miguel Ferreira, Raquel Miriam Vieira-Sousa, Elsa Barreira, Sofia
...
Published in
Arthritis Research & Therapy
BackgroundTo investigate whether the reason to discontinue the first TNF inhibitor (TNFi) affects the response to the second TNFi in axial spondyloarthritis (axSpA).MethodsPatients with axSpA from the Rheumatic Diseases Portuguese Register (ReumaPt), who discontinued their first TNFi and started the second TNFi between June 2008 and May 2018, were ...
Alkan, Gülbin Akkoç, Yeşim Zengin, Berrin Keser, Gökhan Kabasakal, Yasemin Akkoç, Nurullah
Published in
Turkish Journal of Physical Medicine and Rehabilitation
Objectives The aim of this study was to adapt the Assessment of Knowledge in Ankylosing Spondylitis Patients by a Self-Administered Questionnaire for the Turkish ankylosing spondylitis (AS) patients. Patients and methods Between May 2016 and December 2016, a total of 100 AS patients (72 males, 28 females; mean age 43.4 years; range, 21 to 73 years)...
