Desai, Sheena Lo, Kelly Nambudiri, Vinod E Villa-Ruiz, Camila LaChance, Avery Vleugels, Ruth Ann
Published in
Archives of dermatological research
Alopecia areata (AA) is a psychologically distressing disorder for which few reliable treatments exist. Although oral tofacitinib has demonstrated efficacy in treating AA, it is not approved by the Food and Drug Administration (FDA) for this indication. To investigate and identify the challenges associated with securing insurance approval for oral ...
Mostaghimi, Arash Xenakis, Jason Meche, Aster Smith, Timothy W. Gruben, David Sikirica, Vanja
Published in
Dermatology and Therapy
Introduction Comparative data on the economic burden of alopecia areata relative to the general population are limited. The objective of this retrospective database analysis was to evaluate healthcare resource utilization and direct medical costs among patients with alopecia areata from the US payer perspective compared with matched controls. Metho...
Avhad, Ganesh
Published in
International Journal of Trichology
The activity of tofacitinib for Alopecia areata (AA) has been reported but mainly from the western countries. We report the case of a young female Indian patient with AA unresponsive to therapy. Improvements in terms of hair regrowth were observed within 2 months of treatment with oral tofacitinib 5 mg BID tablets. The effectiveness of tofacitinib ...
King, Brett A. Senna, Maryanne M. Ohyama, Manabu Tosti, Antonella Sinclair, Rodney D. Ball, Susan Ko, Justin M. Glashofer, Marc Pirmez, Rodrigo Shapiro, Jerry
...
Published in
Dermatology and Therapy
Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss. As a clinically heterogeneous disease, various classification systems have evolved for defining its severity. In this high-level review of the literature, we discuss the traditional classification systems for AA severity and their strengths and weaknesses. Most re...
Gelhorn, Heather L. Cutts, Katelyn Edson-Heredia, Emily Wright, Peter Delozier, Amy Shapiro, Jerry Senna, Maryanne Tosti, Antonella
Published in
Dermatology and Therapy
Introduction Alopecia areata (AA) is an autoimmune disease characterized by hair loss. Patients with AA experience a range of social and emotional impacts, and the lack of effective treatments and multiple affected locations can deepen the burden of illness. The objective of the current study was to assess health-related quality of life (HRQL) amon...
AL-Eitan, Laith N. Alghamdi, Mansour A. Al Momani, Rawan O. Aljamal, Hanan A. Abdalla, Asim M. Mohammed, Heitham M.
Published in
Heliyon
Alopecia areata; Hair follicles; Autoimmunity; Gene polymorphisms; Genetic markers; TLR1 .
Elosua-González, Marta Rosell-Díaz, Ángel Alfageme-Roldán, Fernando Sigüenza-Sanz, Mercedes Roustan-Gullón, Gaston
Published in
Anais Brasileiros de Dermatologia
Atopic dermatitis predisposes to skin infections, and on the other hand, some therapies used for atopic dermatitis may worsen viral infections whose lesions may be more diffuse and resistant to treatment. The authors present a patient with severe atopic dermatitis and disseminated molluscum contagiosum infection. The molluscum contagiosum did not c...
Younes, Abdel-Khalek Hammad, Refaat Othman, Mona Sobhy, Ali
Published in
BMC Immunology
Background Alopecia areata (AA) is a common inflammatory disorder targeting the hair follicles leading to non-scaring hair loss. The pathogenesis of AA is still unclear, despite the accumulating evidence of the immune-mediated nature of this disease. So, in this study, we aimed to assess the level of CD4 T cells, CD8 T cells and natural killer (NK)...
de Sousa, Vando Barbosa Arcanjo, Francisco Placido Aguiar, Fernando Vasconcelos, Jaqueline Oliveira, Antonio Flavio Honório, Aline Pontes, Juliana
Published in
The Journal of dermatological treatment
Betamethasone can be used for intralesional infiltration, but there is little evidence in the literature to indicate its effectiveness in alopecia areata. To assess the safety and effectiveness of the use of different doses of intralesional betamethasone, when compared to triamcinolone acetonide for the treatment of alopecia areata. We recruited 12...
Song, Ahreum Lee, Sang Eun Kim, Jong Hoon
Published in
Immune Network
Recently, there have been impressive advancements in understanding of the immune mechanisms underlying cutaneous inflammatory diseases. To understand these diseases on a deeper level and clarify the therapeutic targets more precisely, numerous studies including in vitro experiments, animal models, and clinical trials have been conducted. This has r...
