BackgroundOlder people are often admitted for rehabilitation to improve walking, yet not everyone improves. The aim of this study was to determine key factors associated with a positive response to hospital-based rehabilitation in older people.MethodsThis was a secondary data analysis from a multisite randomized controlled trial. Older people (n= 1...
Wylensek, DavidHitch, Thomas CARiedel, ThomasAfrizal, AfrizalKumar, NeerajWortmann, EstherLiu, TianzheDevendran, SaravananLesker, Till RHernández, Sara B
...
Aberrant neural oscillations hallmark numerous brain disorders. Here, we first report a method to track the phase of neural oscillations in real-time via endpoint-corrected Hilbert transform (ecHT) that mitigates the characteristic Gibbs distortion. We then used ecHT to show that the aberrant neural oscillation that hallmarks essential tremor (ET) ...
INTRODUCTION: Patients with diabetes mellitus admitted to hospital with COVID-19 have poorer outcomes. However, the drivers for this are not fully elucidated. We performed detailed characterisation of COVID-19 patients to determine clinical and biochemical factors that may be the drivers of poorer outcomes. RESEARCH DESIGN AND METHODS: Retrospectiv...
BackgroundVertigo, dizziness and balance disorders (VDB) are among the most relevant contributors to the burden of disability among older adults living in the community and associated with immobility, limitations of activities of daily living and decreased participation. The aim of this study was to identify the quality of evidence of physical ther...
Horby, PeterMafham, MarionLinsell, LouiseBell, Jennifer LStaplin, NatalieEmberson, Jonathan RWiselka, MartinUstianowski, AndrewElmahi, EinasPrudon, Benjamin
...
BACKGROUND: Hydroxychloroquine and chloroquine have been proposed as treatments for coronavirus disease 2019 (Covid-19) on the basis of in vitro activity and data from uncontrolled studies and small, randomized trials. METHODS: In this randomized, controlled, open-label platform trial comparing a range of possible treatments with usual care in pati...
Sin, JElkes, JBatchelor, RHenderson, CGillard, SWoodham, LAChen, TAden, ACornelius, V
Background: Family carers supporting an individual with psychosis often experience distress associated with caregiving responsibility. However, scarce research evidence exists investigating mental health morbidities in carers of people with psychosis. Methods: We conducted an online cross-sectional study with adult carers supporting a relative or c...
The biological mechanisms involved in SARS-CoV-2 infection are only partially understood. Thus we explored the plasma metabolome of patients infected with SARS-CoV-2 to search for diagnostic and/or prognostic biomarkers and to improve the knowledge of metabolic disturbance in this infection. We analyzed the plasma metabolome of 55 patients infected...
