Background Harmful alcohol consumption in older people has increased and effective approaches to understanding and addressing this societal concern are needed. Methods Systematic review of qualitative studies in older populations (55+ years) to identify barriers, facilitators or context of drinking in older people. Multiple databases (MEDLINE, EMBA...
Background Harmful alcohol consumption in older people has increased and effective approaches to understanding and addressing this societal concern are needed. Methods Systematic review of qualitative studies in older populations (55+ years) to identify barriers, facilitators or context of drinking in older people. Multiple databases (MEDLINE, EMBA...
Background & Aims We analyzed DNA methylation patterns and transcriptomes of primary intestinal epithelial cells (IEC) of children newly diagnosed with inflammatory bowel diseases (IBD) to learn more about pathogenesis. Methods We obtained mucosal biopsies (n=236) collected from terminal ileum and ascending and sigmoid colons of children (median ag...
Background & Aims We analyzed DNA methylation patterns and transcriptomes of primary intestinal epithelial cells (IEC) of children newly diagnosed with inflammatory bowel diseases (IBD) to learn more about pathogenesis. Methods We obtained mucosal biopsies (n=236) collected from terminal ileum and ascending and sigmoid colons of children (median ag...
Atrial arrhythmias, most commonly manifesting as atrial fibrillation (AF), represent a major clinical problem. AF incidences increase with both age and conditions associated with energetic dysfunction. Atrial arrhythmic phenotypes were compared in young (12-16 week) and aged (>52 week), WT and peroxisome proliferator receptor gamma co-activator 1β-...
FEM receives funding from the Medical Research Council (MC U105292687).
FEM receives funding from the Medical Research Council (MC U105292687).
