Alotaibi, Bader S. Wu, Chia-Hung Khan, Majid Nawaz, Mohsin Chen, Chien-Chin Ali, Abid
Published in
Frontiers in Veterinary Science
African swine fever is a hemorrhagic disease of pigs with high mortality rates. Since its first characterization in 1921, there has been sufficient information about African swine fever virus (ASFV) and related diseases. The virus has been found and maintained in the sylvatic cycle involving ticks and domestic and wild boars in affected regions. Th...
Zhang, Mengjia Lang, Yifei Li, Wentao
Published in
Microbiology Spectrum
The emergence and spread of the African swine fever virus (ASFV) posed a significant threat to the global swine breeding industry, calling for innovative approaches benefiting viral containment and control. A recent study (Z. Zheng, L. Xu, H. Dou, Y. Zhou, X., et al., Microbiol Spectr 12: e02164-23, 2024, https://doi.org/10.1128/spectrum.02164-23) ...
He, Jian Li, Jieqiong Luo, Mingzhan Liu, Yangkun Sun, Jingchen Yao, Lunguang
Published in
Frontiers in Veterinary Science
African swine fever (ASF) is a highly fatal infectious disease in pigs, caused by the African swine fever virus (ASFV). It is characterized by short disease duration and high morbidity and mortality. In August 2018, ASF was first reported in China and it subsequently spread rapidly throughout the country, causing serious economic losses for the Chi...
Zhu, Junhai Chen, Huahan Gao, Fei Jian, Weijun Huang, Guangyu Sunkang, Yongjie Chen, Xiaona Liao, Ming Zhang, Kehui Qi, Wenbao
...
Published in
Journal of Virology
The urgency and severity of African swine fever (ASF) underscore the critical need for effective interventions against this highly infectious disease, which poses a grave threat to domestic pigs and wild boars. Our study reveals the potent anti-African swine fever virus (ASFV) efficacy of bis-benzylisoquinoline alkaloids (BBAs), particularly eviden...
Zhu, Junhai Chen, Huahan Gao, Fei Jian, Weijun Huang, Guangyu Sunkang, Yongjie Chen, Xiaona Liao, Ming Zhang, Kehui Qi, Wenbao
...
Published in
Journal of Virology
The urgency and severity of African swine fever (ASF) underscore the critical need for effective interventions against this highly infectious disease, which poses a grave threat to domestic pigs and wild boars. Our study reveals the potent anti-African swine fever virus (ASFV) efficacy of bis-benzylisoquinoline alkaloids (BBAs), particularly eviden...
Gladue, Douglas P. Gomez-Lucas, Lidia Largo, Eneko Ramirez-Medina, Elizabeth Torralba, Johana Queralt-Martín, Maria Alcaraz, Antonio Velazquez-Salinas, Lauro Nieva, Jose L. Borca, Manuel V.
...
Published in
Journal of Virology
African swine fever (ASF), a devastating disease affecting domestic swine, is widely spread in Eurasia, producing significant economic problems in the pork industry. Approaches to prevent/cure the disease are mainly restricted to the limited information concerning the role of most of the genes encoded by the large (160–170 kba) virus genome. In thi...
Gladue, Douglas P. Gomez-Lucas, Lidia Largo, Eneko Ramirez-Medina, Elizabeth Torralba, Johana Queralt-Martín, Maria Alcaraz, Antonio Velazquez-Salinas, Lauro Nieva, Jose L. Borca, Manuel V.
...
Published in
Journal of Virology
African swine fever (ASF), a devastating disease affecting domestic swine, is widely spread in Eurasia, producing significant economic problems in the pork industry. Approaches to prevent/cure the disease are mainly restricted to the limited information concerning the role of most of the genes encoded by the large (160–170 kba) virus genome. In thi...
Sampedro, Fernando Urriola, Pedro E. van de Ligt, Jennifer L. G. Schroeder, Declan C. Shurson, Gerald C.
Published in
Frontiers in Veterinary Science
Introduction There are no microbiological regulatory limits for viruses in animal feed and feed ingredients. Methods A performance objective (PO) was proposed in this study to manufacture a spray-dried porcine plasma (SDPP) batch absent of any infectious viral particles. The PO levels of −7.0, −7.2, and −7.3 log TCID50/g in SDPP were estimated for ...
Vlasov, Mikhail E. Nefedeva, Mariia V. Kudryashov, Dmitriy A. Titov, Ilya A.
Published in
Acta Veterinaria
African swine fever continues to pose a global agricultural problem due to the absence of vaccine prevention and the high cost of anti-epizootic measures. This study examines the functional role of the African swine fever virus (ASFV) 1L-5-6L multigene family 110 genes in vivo. Four clinically healthy Large White pigs were used in this study. Two g...
Moorton, Madison Tng, Priscilla Y. L. Inoue, Ryo Netherton, Christopher L. Gerner, Wilhelm Schmidt, Selma
Published in
Frontiers in Veterinary Science
Activation-induced markers (AIMs) are frequently analyzed to identify re-activated human memory T cells. However, in pigs the analysis of AIMs is still not very common. Based on available antibodies, we designed a multi-color flow cytometry panel comprising pig-specific or cross-reactive antibodies against CD25, CD69, CD40L (CD154), and ICOS (CD278...