Lu, Y-Thanh Gunathilake, Madhawa Lee, Jeonghee Oh, Jae Hwan Chang, Hee Jin Sohn, Dae Kyung Shin, Aesun Kim, Jeongseon
Published in
European journal of nutrition
The glycemic index (GI), glycemic load (GL), and adiponectin level contribute to glycemic response and insulin sensitivity in the body. Studies have shown that tumor development is related to glycemic disorders; however, the results are contradictory. We aimed to investigate the association of GI and GL with colorectal cancer (CRC) risk in a Korean...
Jang, Albert Youngwoo Scherer, Philipp E Kim, Jang Young Lim, Soo Koh, Kwang Kon
Published in
Cardiovascular research
Adiponectin is an adipocyte-derived cytokine known for its cardioprotective effects in preclinical studies. Early epidemiologic studies replicated these findings and drew great interest. Subsequent large-scale prospective cohorts, however, showed that adiponectin levels seemed not to relate to incident coronary artery disease (CAD). Even more surpr...
Zhang, Yan-Qing Fan, Sen Wang, Wen-Qing Lau, Wayne Bond Dai, Jian-Li Zhang, Hai-Feng Wang, Xiao-Ming Liu, Xiao-Gang Li, Rong
Published in
Journal of diabetes investigation
Adiponectin is a potent vascular protective molecule. Recent findings have suggested adiponectin resistance during early diabetes. However, the molecular mechanisms responsible remain unidentified. Here, we took an unbiased approach to identify whether hyperlipidemic plasma molecules exist that bind and inhibit adiponectin function, contributing to...
Toutouzas, Konstantinos Antonopoulos, Alexios S Koutagiar, Iosif Skoumas, Ioannis Benetos, Georgios Kafouris, Pavlos Miliou, Antigoni Petrocheilou, Aikaterini Georgakopoulos, Alexandros Oikonomou, Georgios
...
Published in
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
The role of adipose tissue (AT) in arterial inflammation in familial dyslipidaemias is poorly studied. We investigated the relationship between AT and arterial inflammation in patients with heterozygous familial hypercholesterolemia (heFH) and familial combined hyperlipidemia (FCH). A total of 40 patients (20 heFH/20 FCH) and a subgroup of 20 of no...
Petrikis, Petros Karampas, Andreas Leondaritis, George Markozannes, Georgios Archimandriti, Dimitra T Spyrou, Polyxeni Georgiou, Georgios Skapinakis, Petros Voulgari, Paraskevi V
Published in
Journal of psychosomatic research
There is increasing evidence that adiponectin, resistin and leptin may be implicated in the pathophysiology of neuropsychiatric disorders, including schizophrenia. The results of the studies so far remain controversial. Our aim was to compare serum adiponectin, leptin and resistin levels between drug-naïve, first -episode patients with psychosis an...
Xie, Minghao Xiong, Zhizhong Yin, Shi Xiong, Jiaqing Li, Xianzhe Jin, Longyang Zhang, Fengxiang Chen, Huaxian Lan, Ping Lian, Lei
...
Published in
Digestive diseases and sciences
Intestinal fibrosis is a common complication of Crohn's disease (CD). Adiponectin reportedly exerts anti-inflammatory effects in various disease models, including colitis models. In this study, we aimed to determine the effects of adiponectin on intestinal fibrosis and the underlying mechanisms. A murine model of intestinal fibrosis was established...
Schaffer, Annamária Ducza, Eszter Bódi, Nikolett Bagyánszki, Mária Szalai, Zita Mirdamadi, Mohsen Barna, Tamara Szűcs, Kálmán F Gáspár, Róbert
Published in
Life sciences
Limited data are available about the functions and expressions of leptin and adiponectin receptors (LEPR, AdipoRs) in the uterus. Our aim was to investigate the effects of leptin and adiponectin on the contractions of intact and denuded nonpregnant and pregnant uteri, as well as the changes in mRNA and protein expressions of LEPR and AdipoRs during...
Hamann, Tine Volquartzen Mørk, Freja Cecilie Barrett Jensen, Andreas Kryger Jørgensen, Niklas Rye Heidemann, Malene Søborg Schou, Anders Jørgen Mølgaard, Christian Pociot, Flemming Wedderkopp, Niels Johannesen, Jesper
...
Published in
Scandinavian journal of clinical and laboratory investigation
The adipokines adiponectin and leptin play key roles in human metabolic regulation and have gained great attention as biomarkers for various metabolic pathologies. Though, pediatric reference values are few and needed. This study aims to establish age- and sex-specific adipokine reference percentiles based on healthy Danish school children. Further...
Machado, M E Porto, L C Alves Galvão, M G Sant Anna, C C Lapa E Silva, J R
Published in
The Journal of asthma : official journal of the Association for the Care of Asthma
Asthma and obesity are complex disorders influenced by environmental and genetic factors. We performed an integrative review of genetic polymorphisms and adipokines effects in children and adolescents with asthma and obesity. Articles focused on these issues were collected from SciELO, PubMed, LILACS, Embase and ScienceDirect electronic databases, ...
El Amrousy, Doaa El-Afify, Dalia Salah, Shaimaa
Published in
BMC Pediatrics
Background Obesity usually complicates hypothyroidism. Adipokines like leptin and adiponectin secreted by adipose tissue modulate insulin resistance (IR), appetite, and obesity. The association between adipokines, IR, and thyroid hormone has not been sufficiently studied in children. We investigated leptin and adiponectin as well as IR and their as...
