De Zutter, Noémie Ameye, Maarten Vermeir, Pieter Verwaeren, Jan De Gelder, Leen Audenaert, Kris
Published in
Microbiology Spectrum
The use of phosphate solubilizing bacteria (PSB) as inoculants for the rhizosphere is a well-known strategy to mitigate P-deficiency in plants. However, despite the multiple modes of action to render P available for plants, PSB often fail to deliver in the field as their selection is often based on a single P-solubilizing trait assessed in vitro. A...
Aerts, Robina; 139786; Mercier, Toine; 76422; Houben, Els; 48337; Schauwvlieghe, Alexander; Lagrou, Katrien; 18511; Maertens, Johan; 58385;
Early diagnosis of invasive aspergillosis is an important factor to improve survival but remains challenging. The detection of Aspergillus antigens is included in the consensus case definitions of the European Organization for Research and Treatment of Cancer and the National Institute of Allergy and Infectious Diseases Mycoses Study Group as a cri...
Jullien, S Fitzgerald, F Keddie, S Baerenbold, O Bassat, Q Bradley, J Falconer, J Fink, C Keogh, R Hopkins, H
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Respiratory syncytial virus (RSV) and influenza viruses are important global causes of morbidity and mortality. We evaluated the diagnostic accuracy of the Luminex NxTAG respiratory pathogen panels (RPPs)™ (index) against other RPPs (comparator) for detection of RSV and influenza viruses. Studies comparing human clinical respiratory samples tested ...
Mamode, Nizam; Bestard, Oriol; Claas, Frans; Furian, Lucrezia; Griffin, Sian; Legendre, Christophe; Pengel, Liset; Naesens, Maarten; 50272;
This guideline, from a European Society of Organ Transplantation (ESOT) working group, concerns the management of kidney transplant patients with HLA antibodies. Sensitization should be defined using a virtual parameter such as calculated Reaction Frequency (cRF), which assesses HLA antibodies derived from the actual organ donor population. Highly ...
Oeyen, Merel; 104656; Meyen, Eef; Doijen, Jordi; Schols, Dominique; 9441;
In this study, we use electric cell-substrate impedance sensing (ECIS), an established cell-based electrical impedance (CEI) technology, to decipher the kinetic cytopathic effect (CPE) induced by Zika virus (ZIKV) in susceptible human A549 lung epithelial cells and to evaluate several classes of compounds with reported antiviral activity (two entry...
Kim, H Yeow, J Najer, A Kit-Anan, W Wang, R Rifaie Graham, O Thanapongpibul, C Stevens, M
Constructing artificial systems that effectively replace or supplement natural biological machinery within cells is one of the fundamental challenges underpinning bioengineering. At the sub-cellular scale, artificial organelles (AOs) have significant potential as long-acting biomedical implants, mimicking native organelles by conducting intracellul...
Li, Jing Evon, Philippe Ballas, Stéphane Trinh, Hoang Khai Xu, Lin Van Poucke, Christof Van Droogenbroeck, Bart Motti, Pierfrancesco Mangelinckx, Sven Ramirez, Aldana
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Published in
Frontiers in Plant Science
A survey of plant-based wastes identified sunflower (Helianthus annuus) bark extract (SBE), produced via twin-screw extrusion, as a potential biostimulant. The addition of SBE to Arabidopsis (Arabidopsis thaliana) seedlings cultured in vitro showed a dose-dependent response, with high concentrations causing severe growth inhibition. However, when p...
Tan, Shuai; Groaz, Elisabetta; 54902; Kalkeri, Raj; Ptak, Roger; Korba, Brent E; Herdewijn, Piet; 10383;
Minor structural modifications of acyclic nucleoside phosphonates can dramatically affect their antiviral properties. This work discloses a shift in the selectivity spectrum of 3-hydroxy-2-(phosphonomethoxy)propyl (HPMP) nucleotides from herpesviruses toward hepatitis B virus (HBV) induced by their acyclic chain 2-substitution with a nonpolar group...
Shaw, Philip Anthony Gilbert; Panda, Sujogya Kumar; Stanca, Alexandru; Luyten, Walter; 43285;
BACKGROUND: Locomotor assays in zebrafish have emerged as a screening test in early drug discovery for antiseizure compounds. However, parameters differ considerably between published studies, which may explain some discrepant results with (candidate) antiseizure medications. NEW METHOD: We optimized a locomotor-based seizure assay in zebrafish wit...
Salim, Hiba Pero-Gascon, Roger Giménez, Estela Benavente, Fernando
Published in
Analytical chemistry
In this paper, we present a fully integrated valve-free method for the sensitive targeted bottom-up analysis of proteins through on-line aptamer affinity solid-phase extraction and immobilized enzyme microreactor capillary electrophoresis-mass spectrometry (AA-SPE-IMER-CE-MS). The method was developed analyzing α-synuclein (α-syn), which is a prote...
