Lee, Juhee Shin, Hyunsu Lee, In-Geun Ko, Dae-Hong
Published in
Journal of the Korean Physical Society
We investigated defect generation in GaAs and InP on various blanket Si substrates and Si patterns with nanosized trench structures via transmission electron microscopy. The dependences of types of defects on the substrate orientation and the pattern size in GaAs and InP on nanosized patterns were analyzed. Defects that formed in a specific directi...
Hughes, Carolyn Smith Brown, Joelle Murombedzi, Caroline Chirenda, Thandiwe Chareka, Gift Mhlanga, Felix Mateveke, Bismark Gitome, Serah Makurumure, Tinei Matubu, Allen
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Published in
BMC Health Services Research
BackgroundIn recent years, safer conception strategies have been developed to help HIV-serodiscordant couples conceive a child without transmitting HIV to the seronegative partner. The SAFER clinical trial assessed implementation of these strategies in Zimbabwe.MethodsAs a part of the SAFER study, we estimated the costs (in 2017 $US) associated wit...
Poku, Ohemaa B. Ho-Foster, Ari R. Entaile, Patlo Misra, Supriya Mehta, Haitisha Rampa, Shathani Goodman, Melody Arscott-Mills, Tonya Eschliman, Evan Jackson, Valerie
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Published in
Trials
BackgroundWith high rates of HIV and multiple vulnerable subgroups across diverse settings, there is a need for culturally based, HIV stigma reduction interventions. Pregnant women who are living with HIV are especially in need of services to protect not only their own but also their children’s lives. Uptake of HIV services worldwide is hindered by...
Nakalega, Rita Mukiza, Nelson Kiwanuka, George Makanga-Kakumba, Ronald Menge, Robert Kataike, Hajira Maena, Joel Akello, Carolyne Atuhaire, Patience Matovu-Kiweewa, Flavia
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Published in
BMC Infectious Diseases
BackgroundViral load (VL) testing is the gold-standard approach for monitoring human immunodeficiency virus (HIV) treatment success and virologic failure, but uptake is suboptimal in resource-limited and rural settings. We conducted a cross-sectional study of risk factors for non-uptake of VL testing in rural Uganda.MethodsWe conducted a cross-sect...
Stecher, Melanie Chaillon, Antoine Stephan, Christoph Knops, Elena Kohmer, Niko Lehmann, Clara Eberle, Josef Bogner, Johannes Spinner, Christoph D. Eis-Hübinger, Anna Maria
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Published in
Emerging Infectious Diseases
We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy–naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shar...
Loucif, Hamza Dagenais-Lussier, Xavier Beji, Cherifa Telittchenko, Roman Routy, Jean-Pierre van Grevenynghe, Julien
Published in
Cytokine & growth factor reviews
The notion of immuno-metabolism refers to the crosstalk between key metabolic pathways and the development/maintenance of protective immunity in the context of physiological processes and anti-microbial defenses. Enthusiasm for immuno-metabolism in the context of HIV-1 infection, especially among T-cell lineages, continues to grow over time as scie...
Stecher, Melanie Chaillon, Antoine Stephan, Christoph Knops, Elena Kohmer, Niko Lehmann, Clara Eberle, Josef Bogner, Johannes Spinner, Christoph D Eis-Hübinger, Anna Maria
...
We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy-naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shar...
Planas, Delphine Fert, Augustine Zhang, Yuwei Goulet, Jean-Philippe Richard, Jonathan Finzi, Andrés Ruiz, Maria Julia Marchand, Laurence Raymond Chatterjee, Debashree Chen, Huicheng
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Published in
Pathogens and Immunity
The frequency and functions of Th17-polarized CCR6+RORyt+CD4+ T cells are rapidly compromised upon HIV infection and are not restored with long-term viral suppressive antiretroviral therapy (ART). In line with this, Th17 cells represent selective HIV-1 infection targets mainly at mucosal sites, with long-lived Th17 subsets carrying replication-comp...
Kawamara, Kazuhiro Kelsey, Tom Hiraike, Osamu
Published in
Frontiers in Endocrinology
Hughes, Sean M. Levy, Claire N. Calienes, Fernanda L. Stekler, Joanne D. Pandey, Urvashi Vojtech, Lucia Berard, Alicia R. Birse, Kenzie Noël-Romas, Laura Richardson, Brian
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Published in
Cell Reports. Medicine
Many people take the antiretroviral drugs tenofovir and emtricitabine to prevent and treat HIV infection. Hughes et al. show that these medications induce genes and proteins associated with type I/III interferon pathways in the gut. This effect may contribute to HIV inhibition but could also cause chronic immune activation.
