Coupled constitutive equations for assessing Mechanical effects of Internal Swelling Reactions
ICAAR 2021, 16th International Conference on Alkali-Aggregate Reaction in Concrete Structrures, Lisbonne, PORTUGAL, 01-/06/2021 - 03/06/2021
Frequency and reasons for delayed treatment initiation after HIV diagnosis: cross-sectional study in Lahore, Pakistan
Published in BMC Public Health
BackgroundWell-timed initiation of HIV therapy enhances life expectancy, decreases mortality and morbidity, and inhibits the transmission of HIV and complications related to it. The purpose of the present survey is to investigate the frequency and reasons for delayed initiation of anti-retroviral therapy (ART) and to determine its relationship with...
Optimal intervention strategies of staged progression HIV infections through an age-structured model with probabilities ...
In this paper, we construct a model to describe the transmission of HIV in a homogeneous host population. By considering the specific mechanism of HIV, we derive a model structured in three successive stages: (i) primary infection, (ii) long phase of latency without symptoms and (iii) AIDS. Each HIV stage is stratified by the duration for which ind...
Predictive factors of viral load high-risk events for virological failure in HIV/AIDS patients receiving long-term antiv...
...Published in BMC Infectious Diseases
BackgroundIn the era of anti-retroviral therapy (ART), the plasma HIV viral load (VL) is an important primary indicator for monitoring the HIV treatment response. To optimize the clinical management of HIV/AIDS patients, we investigated VL high-risk events related to virological failure (VF) and further explored the preventive factors of VL high-ri...
Predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy in Metema Hospital, Northwest E...
Published in AIDS Research and Therapy
BackgroundGlobally Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) is an ongoing public health issue associated with high morbidity and mortality. Efforts have been made to reduce HIV/AIDS-related morbidity and mortality by delivering antiretroviral therapy. However, the incidence and predictors of mortality in border ar...
Employment trajectories of PLHIV on ART in Lusaka, Zambia: a short report.
Published in AIDS care
The introduction of antiretroviral therapy (ART) has helped mitigate many of the negative consequences of HIV. ART allows people living with HIV (PLHIV) to recover physically and become active members of society. Research thus far is positive about the potential economic impact of ART on household economies. In terms of employment, studies indicate...
Survival of HIV/AIDS patients treated under ART follow-up at the University hospital, northwest Ethiopia
Published in Environmental Health and Preventive Medicine
IntroductionThe survival of HIV/AIDS patients on antiretroviral therapy (ART) is determined by a number of factors, including economic, demographic, behavioral, and institutional factors. Understanding the survival time and its trend is crucial to developing policies that will result in changes. The aim of this study was to compare the survival est...
Neurocognitive function among HIV-infected children on protease inhibitor -based versus non-protease inhibitor based ant...
Published in BMC Pediatrics
BackgroundHIV infection is associated with significant neurocognitive deficits making maximization of cognitive function among children receiving antiretroviral therapy (ART) a public health imperative. Non-protease inhibitors (non-PIs) achieve higher drug levels in the cerebral spinal fluid (CSF) compared to PIs, potentially leading to better neur...
Linkage to intensive adherence counselling among HIV-positive persons on ART with detectable viral load in Gomba distric...
...Published in AIDS Research and Therapy
BackgroundAntiretroviral therapy (ART) adherence is a primary determinant of sustained viral suppression, HIV transmission risk, disease progression and death. The World Health Organization recommends that adherence support interventions be provided to people on ART, but implementation is suboptimal. We evaluated linkage to intensive adherence coun...
STING and cGAS gene expressions were downregulated among HIV-1-infected persons after antiretroviral therapy
...Published in Virology Journal
BackgroundThe HIV-1 epidemic is still considered a global public health problem, but great advances have been made in fighting it by antiretroviral therapy (ART). ART has a considerable impact on viral replication and host immunity. The production of type I interferon (IFN) is key to the innate immune response to viral infections. The STING and cGA...
