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Comparison of 200 mg Cimetidine with Multiple Doses of Antacid on Extent and Duration of Rise in Gastric pH in Volunteer...

Published in Digestive Diseases and Sciences

The effects on gastric pH of a singleadministration of 200 mg cimetidine (Tagamet HB) werecompared to multiple doses of a liquid antacid (Mylanta)using a pH microelectrode. Gastric pH was monitored for 8 hr in 20 normal fasting volunteers in acrossover design to compare Tagamet HB (two 100-mgtablets administered as a single dose) with MylantaSuspen...