Noonan, Megan L Ni, Pu Agoro, Rafiou Sacks, Spencer A Swallow, Elizabeth A Wheeler, Jonathan A Clinkenbeard, Erica L Capitano, Maegan L Prideaux, Matthew Atkins, Gerald J
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Published in
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Fibroblast growth factor-23 (FGF23) is a critical factor in chronic kidney disease (CKD), with elevated levels causing alterations in mineral metabolism and increased odds for mortality. Patients with CKD develop anemia as the kidneys progressively lose the ability to produce erythropoietin (EPO). Anemia is a potent driver of FGF23 secretion; there...
D'Souza, N Monahan, K Benton, SC Wilde, L Abulafi, M
Aim Detection of early onset colorectal cancer is challenging, and remains a rare diagnosis amongst younger people with gastrointestinal symptoms. We investigated whether faecal immunochemical testing (FIT) could identify younger patients at higher risk of colorectal cancer or serious bowel disease including colorectal cancer, inflammatory bowel di...
Bredeche, Faustine Gounot, Isabelle Belgaïd, Vincent Macabeo, Caroline Rouhana, Kaissar Aubrun, Frederic Ferry, Tristan Servien, Elvire Lustig, Sebastien Dziadzko, Mikhail
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Published in
SICOT-J
Preoperative anemia in patients undergoing a two-stage septic revision arthroplasty may be a factor of reinfection, even in the presence of aggressive antimicrobial therapy. Patient Blood Management (PBM) in such patients is challenging. We evaluate the impact of anemia existing before re-implantation on a failure rate after two-stage septic total ...
Zivna, Martina; Kidd, Kendrah; Zaidan, Mohamad; Vyletal, Petr; Baresova, Veronika; Hodanova, Katerina; Sovova, Jana; Hartmannova, Hana; Votruba, Miroslav; Treslova, Helena;
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There have been few clinical or scientific reports of autosomal dominant tubulointerstitial kidney disease due to REN mutations (ADTKD-REN), limiting characterization. To further study this, we formed an international cohort characterizing 111 individuals from 30 families with both clinical and laboratory findings. Sixty-nine individuals had a REN ...
Turusheva, Anna; Vaes, Bert; 87897; Degryse, Jean-Marie; 5966; Frolova, Elena;
BACKGROUND: The relationship of total cholesterol (TC) levels with mortality among older adults without statin therapy has not been fully studied. AIMS: To examine the relationship between TC and all-cause mortality in adults aged 65 years and older in Russia without statin therapy. METHODS: This was a population-based prospective cohort study of c...
Panoskaltsis, N McCarthy, NE Knight, SC
TGN1412, a superagonist monoclonal antibody targeting CD28, caused cytokine storm in six healthy volunteers in a first-in-man study in 2006. Despite clinical improvement and termination of the cytokine release syndrome within days, anemia persisted in all patients with hemoglobin reaching baseline levels as much as 6 months later. Granulocytic dysp...
Kim, Kyoung Min Lui, Li-Yung Cauley, Jane A Ensrud, Kristine E Orwoll, Eric S Schousboe, John T Cummings, Steven R
Published in
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Red cell distribution width (RDW), routinely assessed as a component of a complete blood count (CBC), quantifies the variation in the size of red blood cells. It increases with age, and increased RDW predicts many aging-related diseases and mortality. However, whether it also predicts hip fracture is unknown. We prospectively evaluated the associat...
Brunet, Philippe Choukroun, Gabriel Moulin, Bruno Zaoui, Philippe Thervet, Éric Frimat, Luc Chazot, Charles
Published in
Nephrologie & therapeutique
The French-speaking Society of Nephrology, Dialysis and Transplantation conducted, in 2018, a survey among French nephrologists into their iron prescribing habits for patients with chronic kidney disease stages 3 to 5 before dialysis. The results show that 73% of nephrologists use intravenous iron before dialysis stage. When a patient has gastroint...
Roijers, Joost P; Rakke, Yannick S; Hopmans, Cornelis J; Buimer, Mathijs G; de Groot, Hans GW; Ho, Gwan H; Veen, Eelco J; Mulder, Paul GH; van der Laan, Lijckle; 73118;
OBJECTIVE: Delirium is associated with adverse outcomes, such as increased mortality and prolonged hospital stay. Information on the risk factors for delirium in elderly patients with critical limb ischaemia (CLI) is scarce. The aim of this study was to analyse the incidence of delirium and to identify risk factors for delirium in elderly patients ...
Akin, Sakir; Soliman, Osama; de By, Theo MMH; Muslem, Rahatullah; Tijssen, Jan GP; Schoenrath, Felix; Meyns, Bart; 11101; Gummert, Jan F; Mohacsi, Paul; Caliskan, Kadir;
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PURPOSE: The aim of the study was to analyze early mortality after continuous-flow left ventricular assist device (LVAD) implantation which remains high. METHODS: We analyzed consecutive (n = 2689) patients from the European Registry for Patients with Mechanical Circulatory Support (EUROMACS) undergoing continuous-flow LVAD implantation. The primar...
