Bredeche, Faustine Gounot, Isabelle Belgaïd, Vincent Macabeo, Caroline Rouhana, Kaissar Aubrun, Frederic Ferry, Tristan Servien, Elvire Lustig, Sebastien Dziadzko, Mikhail
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Published in
SICOT-J
Preoperative anemia in patients undergoing a two-stage septic revision arthroplasty may be a factor of reinfection, even in the presence of aggressive antimicrobial therapy. Patient Blood Management (PBM) in such patients is challenging. We evaluate the impact of anemia existing before re-implantation on a failure rate after two-stage septic total ...
Kim, Kyoung Min Lui, Li-Yung Cauley, Jane A Ensrud, Kristine E Orwoll, Eric S Schousboe, John T Cummings, Steven R
Published in
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Red cell distribution width (RDW), routinely assessed as a component of a complete blood count (CBC), quantifies the variation in the size of red blood cells. It increases with age, and increased RDW predicts many aging-related diseases and mortality. However, whether it also predicts hip fracture is unknown. We prospectively evaluated the associat...
Akin, Sakir; Soliman, Osama; de By, Theo MMH; Muslem, Rahatullah; Tijssen, Jan GP; Schoenrath, Felix; Meyns, Bart; 11101; Gummert, Jan F; Mohacsi, Paul; Caliskan, Kadir;
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PURPOSE: The aim of the study was to analyze early mortality after continuous-flow left ventricular assist device (LVAD) implantation which remains high. METHODS: We analyzed consecutive (n = 2689) patients from the European Registry for Patients with Mechanical Circulatory Support (EUROMACS) undergoing continuous-flow LVAD implantation. The primar...
Fenaux, Pierre Platzbecker, Uwe Mufti, Ghulam J Garcia-Manero, Guillermo Buckstein, Rena Santini, Valeria Díez-Campelo, María Finelli, Carlo Cazzola, Mario Ilhan, Osman
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Published in
The New England journal of medicine
Patients with anemia and lower-risk myelodysplastic syndromes in whom erythropoiesis-stimulating agent therapy is not effective generally become dependent on red-cell transfusions. Luspatercept, a recombinant fusion protein that binds transforming growth factor β superfamily ligands to reduce SMAD2 and SMAD3 signaling, showed promising results in a...
Hastuti, Agustina Ari Murti Budi Costas Rodriguez, Marta Anoshkina, Yulia Parnall, Taylor Madura, James A. Vanhaecke, Frank
Bariatric surgery is an effective procedure to achieve weight loss in obese patients. However, homeostasis of essential metals may be disrupted as the main absorption site is bypassed. In this study, we determined Cu, Fe and Zn isotopic compositions in paired serum and whole blood samples of patients who underwent Roux-en-Y gastric bypass (RYGB) su...
Philip, K Hopkinson, N Michael, P Sadaka, A Steptoe, A Fancourt, D
Background: Iron is central to multiple biological pathways, and treatment of non-anaemic absolute iron deficiency (NAID) is beneficial in certain conditions. However, it is unknown if NAID is associated with increased mortality in older-adults. Methods: A nationally representative sample of 4451 older-adults from the English Longitudinal Study of ...
Clarke, NE Dinh, N-N Traub, RJ Clements, ACA Halton, K Anderson, RM Gray, DJ Coffeng, LE Kaldor, JM Nery, SV
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Background Current guidelines and targets for soil-transmitted helminth (STH) control focus on school-based deworming for school-age children, given the high risk of associated morbidity in this age group. However, expanding deworming to all age groups may achieve improved STH control among both the community in general and school-age children, by ...
Uyoga, S Macharia, AW Mochamah, G Ndila, CM Nyutu, G Makale, J Tendwa, M Nyatichi, E Ojal, J Otiende, M
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BACKGROUND: Sickle cell disease is the most common severe monogenic disorder in humans. In Africa, 50-90% of children born with sickle cell disease die before they reach their fifth birthday. In this study, we aimed to describe the comparative incidence of specific clinical outcomes among children aged between birth and 5 years with and without sic...
Boedecker, Julia Odhiambo Odour, Francis Lachat, Carl Van Damme, Patrick Kennedy, Gina Termote, Céline
Published in
Maternal & child nutrition
Our study assessed the effectiveness of a community-based participatory approach in increasing micronutrient adequacy of diets of women and young children through agricultural activities and nutrition education in Vihiga County, Western Kenya. Outcome indicators include the mean dietary diversity score (DDS), the percentage of women and children re...
Lee, Eun Ae Shin, Dong Wook Yoo, Jun Hyun Ko, Hyeon Young Jeong, Su Min
Published in
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Anemia is a common health problem in older adults and is associated with risk factors for fracture such as low physical function and low bone mass. The aim of this study was to examine the relationship between anemia and fracture risk in older adults. We conducted a retrospective cohort study from 2003 to 2013. The participants were community-dwell...
