PURPOSE: The purpose of this study is to evaluate the use of fertility-preserving (FP) treatments and fertility counseling that was offered in a cohort of newly diagnosed children with classical Hodgkin lymphoma (cHL). METHODS: In this observational study, boys and girls with cHL aged ≤ 18 years with scheduled treatment according to the EuroNet-PHL...
STUDY QUESTION: What is the impact of the EuroNet-PHL-C2 treatment protocol for children with classical Hodgkin lymphoma (cHL) on gonadal function in girls, based on assessment of serum anti-Müllerian hormone (AMH)? SUMMARY ANSWER: Serum AMH levels decreased after induction chemotherapy and increased during subsequent treatment and 2 years of follo...
BACKGROUND: To overcome knowledge gaps and optimize long-term follow-up (LTFU) care for childhood cancer survivors, the concept of the Survivorship Passport (SurPass) has been invented. Within the European PanCareSurPass project, the semiautomated and interoperable SurPass (version 2.0) will be optimized, implemented, and evaluated at 6 LTFU care c...
En deçà du vide nécessaire et préalable au désir, inscrit dans la structure de chaque sujet, un vide d’une autre nature se retrouve chez les sujets aux fonctionnements limites. L’expérience du vide chez ces sujets est polymorphe. Si certains le ressentent ou s’en plaignent, d’autres ne l’évoquent tout simplement pas. Néanmoins, le vide apparaît au ...
Grâce à l’efficacité des médicaments antirétroviraux (ARV), la mortalité et la morbidité liées à l’épidémie de VIH ont considérablement diminué au cours des dernières décennies. Néanmoins en Afrique, la persistance de nouvelles infections et le développement de résistances aux ARV traduisent les difficultés dans la prévention et la prise en charge....
Objective: To explore a) to what extent patients with serious illness express emotional cues and concerns during advance care planning (ACP) conversations with their general practitioner (GP), b) the content of cues/concerns and c) GPs' responses to cues/concerns. Methods: Cues/concerns and GPs' responses in 20 conversations were coded using the Ve...
Published in Journal of epidemiology and community health
Intensive home visiting for adolescent mothers may help reduce health disparities. Given limited resources, such interventions need to be effectively targeted. We evaluated which mothers were enrolled in the Family Nurse Partnership (FNP), an intensive home-visiting service for first-time young mothers commissioned in >130 local authorities in Engl...
OBJECTIVE: Improved treatment landscape has led to better outcomes for paediatric acute lymphoblastic leukemia (ALL) survivors. As the number of survivors increase, we need to elucidate the long-term quality of life (QoL) and domains of complaints in these patients. Furthermore, the main priorities of these patients need to be clarified. We assesse...
INTRODUCTION: Long-term survival after childhood cancer often comes at the expense of late, adverse health conditions. However, survivorship care is frequently not available for adult survivors in Europe. The PanCareFollowUp Consortium therefore developed the PanCareFollowUp Care Intervention, an innovative person-centred survivorship care model ba...
Published in Health technology assessment (Winchester, England)
A phobia is an intense, ongoing fear of an everyday object or situation. The phobia causes distress and the person with the phobia avoids that object or situation. Many children and young people have phobias that affect their daily lives. Cognitive–behavioural therapy helps by changing what people do or think when they have a phobia and is the most...
