van Roessel, Stijn van Veldhuisen, Eran Klompmaker, Sjors Janssen, Quisette P Abu Hilal, Mohammed Alseidi, Adnan Balduzzi, Alberto Balzano, Gianpaolo Bassi, Claudio Berrevoet, Frederik
...
Published in
JAMA oncology
The benefit of adjuvant chemotherapy after resection of pancreatic cancer following neoadjuvant combination treatment with folinic acid, fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) is unclear. To assess the association of adjuvant chemotherapy with overall survival (OS) in patients after pancreatic cancer resection and neoadjuvant FOLFIR...
Sanikini, H Muller, DC Chadeau-Hyam, M Murphy, N Gunter, MJ Cross, AJ
Background Obesity has been positively associated with upper gastrointestinal cancers, but prospective data by subtype/subsite are limited. Obesity influences hormonal factors, which may play a role in these cancers. We examined anthropometry, body fat and reproductive factors in relation to oesophageal and gastric cancer by subtype/subsite in the ...
Dooley, James; Lagou, Vasiliki; 98844; Goveia, Jermaine; Ulrich, Anna; Rohlenova, Katerina; 116426; Heirman, Nathalie; Karakach, Tobias; Lampi, Yulia; Khan, Shawez; Wang, Jun;
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Pancreatic cancer is a rare but fatal form of cancer, the fourth highest in absolute mortality. Known risk factors include obesity, diet, and type 2 diabetes; however, the low incidence rate and interconnection of these factors confound the isolation of individual effects. Here, we use epidemiological analysis of prospective human cohorts and paral...
Simin, Johanna Tamimi, Rulla M Callens, Steven Engstrand, Lars Brusselaers, Nele
Published in
International journal of cancer
Although menopausal hormone therapy (MHT) seemingly increases the risk of ovarian cancer, evidence is insufficient whether the risk varies between various MHT formulations, regimens and administration modes. With the aim of filling these knowledge gaps, we investigated the effect of different MHT treatment options on the risk of ovarian cancer. Thi...
Christodoulides, N Lami, M Malietzis, G Rasheed, S Tekkis, P Kontovounisios, C
Purpose Sporadic colorectal cancer (CRC) amongst adolescents and young adults (AYA) is increasing in incidence. The reasons for this trend are not well understood. Current guidelines do not specifically address this patient cohort. A scoping review was performed to summarise the range of available evidence and identify key areas that need to be add...
Piron, Sarah De Man, Kathia Schelfhout, Vanessa Van Laeken, Nick Kersemans, Ken Achten, Eric De Vos, Filip Ost, Piet
Published in
EJNMMI Research
BackgroundSeveral scan parameters for PET imaging with 18F-PSMA-11 such as dosage, acquisition time and scan duration were evaluated to determine the most appropriate scan protocol, as well as the effect of furosemide administration on lesion visualization. Forty-four patients were randomly assigned to a dosage group (2.0 ± 0.2 or 4.0 ± 0.4 MBq/kg ...
Hautala, LC Pang, P-C Antonopoulos, A Pasanen, A Lee, C-L Chiu, PCN Yeung, WSB Loukovaara, M Butzow, R Haslam, SM
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Glycodelin is a major glycoprotein expressed in reproductive tissues, like secretory and decidualized endometrium. It has several reproduction related functions that are dependent on specific glycosylation, but it has also been found to drive differentiation of endometrial carcinoma cells toward a less malignant phenotype. Here we aimed to elucidat...
Wagner, Anna D; Lordick, Florian; Grabsch, Heike; Terashima, Masanori; Terada, Mitsumi; Yoshikawa, Takaki; Boku, Narikazu; Kataoka, Kozo; Smyth, Elizabeth C; Mauer, Murielle;
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The aim of this manuscript is to discuss the viewpoint of the European Organisation for Research and Treatment of Cancer (EORTC) Gastric Cancer Taskforce and Japan Clinical Oncology Group (JCOG) Gastric Cancer Study Group on the current challenges in the multidisciplinary management of stage II-III gastric and gastro-oesophageal junction (GEJ) canc...
van der Wel, Myrtle J Coleman, Helen G Bergman, Jacques J G H M Jansen, Marnix Meijer, Sybren L Working Grp, BOLERO Hoorens, Anne
Objective Guidelines mandate expert pathology review of Barrett's oesophagus (BO) biopsies that reveal dysplasia, but there are no evidence-based standards to corroborate expert reviewer status. We investigated BO concordance rates and pathologist features predictive of diagnostic discordance. Design Pathologists (n=51) from over 20 countries asses...
Delaude, Alessandro Raes, Els Leroux, C. Chiers, Koen Sonck, Laurien
An eleven-year-old, female goat was presented for evaluation of breathing difficulties and epistaxis. Radiographs and computed tomographic (CT) examination of the head revealed the presence of a space-occupying lesion involving the right nasal passage and invading the cranial vault and retrobulbar space. Histologic examination and detection of vira...
