Dooley, James; Lagou, Vasiliki; 98844; Goveia, Jermaine; Ulrich, Anna; Rohlenova, Katerina; 116426; Heirman, Nathalie; Karakach, Tobias; Lampi, Yulia; Khan, Shawez; Wang, Jun;
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Pancreatic cancer is a rare but fatal form of cancer, the fourth highest in absolute mortality. Known risk factors include obesity, diet, and type 2 diabetes; however, the low incidence rate and interconnection of these factors confound the isolation of individual effects. Here, we use epidemiological analysis of prospective human cohorts and paral...
Christodoulides, N Lami, M Malietzis, G Rasheed, S Tekkis, P Kontovounisios, C
Purpose Sporadic colorectal cancer (CRC) amongst adolescents and young adults (AYA) is increasing in incidence. The reasons for this trend are not well understood. Current guidelines do not specifically address this patient cohort. A scoping review was performed to summarise the range of available evidence and identify key areas that need to be add...
Piron, Sarah De Man, Kathia Schelfhout, Vanessa Van Laeken, Nick Kersemans, Ken Achten, Eric De Vos, Filip Ost, Piet
Published in
EJNMMI Research
BackgroundSeveral scan parameters for PET imaging with 18F-PSMA-11 such as dosage, acquisition time and scan duration were evaluated to determine the most appropriate scan protocol, as well as the effect of furosemide administration on lesion visualization. Forty-four patients were randomly assigned to a dosage group (2.0 ± 0.2 or 4.0 ± 0.4 MBq/kg ...
Hautala, LC Pang, P-C Antonopoulos, A Pasanen, A Lee, C-L Chiu, PCN Yeung, WSB Loukovaara, M Butzow, R Haslam, SM
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Glycodelin is a major glycoprotein expressed in reproductive tissues, like secretory and decidualized endometrium. It has several reproduction related functions that are dependent on specific glycosylation, but it has also been found to drive differentiation of endometrial carcinoma cells toward a less malignant phenotype. Here we aimed to elucidat...
Simin, Johanna Tamimi, Rulla M Callens, Steven Engstrand, Lars Brusselaers, Nele
Although menopausal hormone therapy (MHT) seemingly increases the risk of ovarian cancer, evidence is insufficient whether the risk varies between various MHT formulations, regimens and administration modes. With the aim of filling these knowledge gaps, we investigated the effect of different MHT treatment options on the risk of ovarian cancer. Thi...
Wagner, Anna D; Lordick, Florian; Grabsch, Heike; Terashima, Masanori; Terada, Mitsumi; Yoshikawa, Takaki; Boku, Narikazu; Kataoka, Kozo; Smyth, Elizabeth C; Mauer, Murielle;
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The aim of this manuscript is to discuss the viewpoint of the European Organisation for Research and Treatment of Cancer (EORTC) Gastric Cancer Taskforce and Japan Clinical Oncology Group (JCOG) Gastric Cancer Study Group on the current challenges in the multidisciplinary management of stage II-III gastric and gastro-oesophageal junction (GEJ) canc...
van der Wel, Myrtle J Coleman, Helen G Bergman, Jacques J G H M Jansen, Marnix Meijer, Sybren L Working Grp, BOLERO Hoorens, Anne
Objective Guidelines mandate expert pathology review of Barrett's oesophagus (BO) biopsies that reveal dysplasia, but there are no evidence-based standards to corroborate expert reviewer status. We investigated BO concordance rates and pathologist features predictive of diagnostic discordance. Design Pathologists (n=51) from over 20 countries asses...
Hoang, LT Domingo-Sabugo, C Starren, ES Willis-Owen, SA Morris-Rosendah, DJ Nicholson, AG Cookson, WOCM Moffatt, MF
Lung cancer is the leading cause of cancer‐related deaths in the world. The most prevalent subtype, accounting for 85% of cases, is non‐small‐cell lung cancer (NSCLC). Lung squamous cell carcinoma (LUSC) and lung adenocarcinoma (LUAD) are the most common subtypes. Despite recent advances in treatment, the low 5‐year survival rate of NSCLC patients ...
Lee, Chia Ching Lim, Keith HC Chia, David WT Chong, Yew Lam Png, Keng Siang Chong, Kian Tai Soon, Yu Yang Tey, Jeremy CS
10.1111/ajco.13197 / ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
Hagens, Eliza RC; Henegouwen, Mark I van Berge; van Sandick, Johanna W; Cuesta, Miguel A; van der Peet, Donald L; Heisterkamp, Joos; Nieuwenhuijzen, Grard AP; Rosman, Camiel; Scheepers, Joris JG; Sosef, Meindert N;
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BACKGROUND: An important parameter for survival in patients with esophageal carcinoma is lymph node status. The distribution of lymph node metastases depends on tumor characteristics such as tumor location, histology, invasion depth, and on neoadjuvant treatment. The exact distribution is unknown. Neoadjuvant treatment and surgical strategy depends...