Buhre, Wolfgang de Korte-de Boer, Dianne de Abreu, Marcelo Gama Scheeren, Thomas Gruenewald, Matthias Hoeft, Andreas Spahn, Donat R. Zarbock, Alexander Daamen, Sylvia Westphal, Martin
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Background: Hydroxyethyl starch (HES) solutions are used for volume therapy to treat hypovolemia due to acute blood loss and to maintain hemodynamic stability. This study was requested by the European Medicines Agency (EMA) to provide more evidence on the long-term safety and efficacy of HES solutions in the perioperative setting. Methods: PHOENICS...
Yang, Hyun Suk Hur, Mina Lee, Kyeong Ryong Kim, Hanah Kim, Hahn Young Kim, Jong Won Chua, Mui Teng Sen Kuan, Win Chua, Horng Ruey Kitiyakara, Chagriya
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10.3343/alm.2022.42.2.178 / ANNALS OF LABORATORY MEDICINE / 42 / 2 / 178-187
Meert, Anne-Pascale Wittnebel, Sebastian Holbrechts, Stéphane Toffart, Anne-Claire Lafitte, Jean-Jacques Piagnerelli, Michael Lemaitre, France Peyrony, Olivier Calvel, Laurent Lemaitre, Jean
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Published in
Intensive care medicine
To respond to the legitimate questions raised by the application of invasive methods of monitoring and life-support techniques in cancer patients admitted in the ICU, the European Lung Cancer Working Party and the Groupe de Recherche Respiratoire en Réanimation Onco-Hématologique, set up a consensus conference. The methodology involved a systematic...
Hassannia, Behrouz Van Coillie, Samya Vanden Berghe, Tom
Published in
Antioxidants & redox signaling
Significance: Iron is an essential element required for growth and proper functioning of the body. However, an excess of labile ferrous iron increases the risk of oxidative stress-induced injury due to the high reactivity of the unpaired reactive electrons of both ferrous iron and oxygen. This high reactivity can be exemplified in the outside world...
Vanmassenhove, Jill Steen, Johan Vansteelandt, Stijn Morzywolek, Pawel Hoste, Eric Decruyenaere, Johan Benoit, Dominique Van Biesen, Wim
Published in
Scientific Reports
Most reports on AKI claim to use KDIGO guidelines but fail to include the urinary output (UO) criterion in their definition of AKI. We postulated that ignoring UO alters the incidence of AKI, may delay diagnosis of AKI, and leads to underestimation of the association between AKI and ICU mortality. Using routinely collected data of adult patients ad...
Vanholder, Raymond Sükrü Sever, Mehmet Lameire, Norbert
Published in
Nephrologie & therapeutique
Mass disasters, particularly earthquakes, cause many medical problems, including kidney problems, but an organized approach to cope with them was initiated only at the end of previous century, subsequent to the Armenian Spitak earthquake in 1988. Originally, interventions were focused on acute kidney injury (AKI) following crush injury and rhabdomy...
Coeman, Laurent WYFFELS, PIET van Limmen, Jurgen Wouters, Patrick
Introduction: During the perioperative period, acute kidney injury (AKI) is a serious complication with increased short- and long-term mortality (1, 2, 3). In former studies, the incidence of AKI following hepatobiliary surgery varied between 5.1 and 15.5% (10, 11, 13-15). The aim of the study is to examine the perioperative risk factors for develo...
Sever, Mehmet Sukru Sever, Lale Vanholder, Raymond
Published in
Pediatric nephrology (Berlin, Germany)
Following disasters, children are physically, psychologically and socially more vulnerable than adults; consequently, their morbidity and mortality are higher. The risks are especially high for orphans and unaccompanied children who are separated from their families, making them frequently victims of human trafficking, slavery, drug addiction, crim...
Sever, Mehmet Sukru Vanholder, Raymond Lameire, Norbert
Published in
Seminars in nephrology
Acute kidney injury (AKI) is frequent during wars and other man-made disasters, and contributes significantly to the overall death toll. War-related AKI may develop as a result of polytrauma, traumatic bleeding and hypovolemia, chemical and airborne toxin exposure, and crush syndrome. Thus, prerenal, intrinsic renal, or postrenal AKI may develop at...
Chua, Horng-Ruey Wong, Weng-Kin Ong, Venetia Huiling Agrawal, Dipika Vathsala, Anantharaman Tay, Hui-Ming Mukhopadhyay, Amartya
10.1177/0885066618764617 / JOURNAL OF INTENSIVE CARE MEDICINE / 35 / 6 / 527-535
