Hoorelbeke, Kristof Van den Bergh, Nathan De Raedt, Rudi Wichers, Marieke Albers, Casper J Koster, Ernst H W
Published in
Emotion (Washington, D.C.)
Studies suggest that cognitive control training shows potential as a preventive intervention for depression. At the same time, little is known regarding the mechanisms underlying effects of cognitive control training. Informed by theoretical frameworks of cognitive risk for recurrent depression (De Raedt & Koster, 2010; Siegle et al., 2007), the cu...
Blanco-Almazan, Dolores; Groenendaal, Willemijn; Lijnen, Lien; Onder, Rana; Smeets, Christophe; Ruttens, David; Catthoor, Francky; 14055; Jane, Raimon;
status: published
Korotkov, Anatoly; Luinenburg, Mark J; Romagnolo, Alessia; Zimmer, Till S; van Scheppingen, Jackelien; Bongaarts, Anika; Broekaart, Diede WM; Anink, Jasper J; Mijnsbergen, Caroline; Jansen, Floor E;
...
BACKGROUND: The genetic disorder tuberous sclerosis complex (TSC) is frequently accompanied by the development of neuropsychiatric disorders, including autism spectrum disorder and intellectual disability, with varying degrees of impairment. These co-morbidities in TSC have been linked to the structural brain abnormalities, such as cortical tubers,...
Schouten, Moniek; 149610; Dalle, Sebastiaan; 107149; Koppo, Katrien; 106641;
Background: Cannabidiol (CBD), a nonintoxicating constituent of the cannabis plant, recently gained a lot of interest among athletes, since it is no longer considered as a prohibited substance by the World Anti-Doping Agency. The increasing prevalence of CBD use among athletes is driven by a perceived improvement in muscle recovery and a reduction ...
Kim, Junhong Yunn, Na-Oh Park, Mangeun Kim, Jihan Park, Seongeun Kim, Yoojoong Noh, Jeongeun RYU, SUNGHO Cho, Yunje
Activation of insulin receptor (IR) initiates a cascade of conformational changes and autophosphorylation events. Herein, we determined three structures of IR trapped by aptamers using cryo-electron microscopy. The A62 agonist aptamer selectively activates metabolic signaling. In the absence of insulin, the two A62 aptamer agonists of IR adopt an i...
Brufani, Giulia; Valentini, Federica; Sabatelli, Flavio; Di Erasmo, Benedetta; Afanasenko, Anastasiia MM; Li, Chao-Jun; Vaccaro, Luigi; 101481;
status: published
Leal, Rodrigo Bainy Mann, Josiane Pinto-Junior, Vanir Reis Oliveira, Messias Vital Da Silva Osterne, Vinicius Jose Victoria Wolin, Ingrid Alessandra Machado Nascimento, Ana Paula Welter, Priscilla Gomes Sousa Ferreira, Valeria Maria Silva, Alice Araujo
...
A glioblastoma (GBM) is a highly malignant primary brain tumor with a poor prognosis because of its invasiveness and high resistance to current therapies. In GBMs, abnormal glycosylation patterns are associated with malignancy, which allows for the use of lectins as tools for recognition and therapy. More specifically, lectins can interact with gly...
Xu, Xianjun; 135180; Huang, Liliang; Smits, Eva; Zhong, Ling; Feng, Huangdi; Van der Eycken, Erik V; 7655;
status: published
Oliveira, Samara Rodrigues Bonfim Damasc... Franco, Álvaro Xavier Quaresma, Marielle Pires de Carvalho, Cecília Mendes Morais da Cunha Jácome Marques, Fabrícia da Silva Pantoja, Patrícia Mendonça, Vanessa Azevedo da Silva Osterne, Vinicius José Correia, Jorge Luis Almeida Assreuy, Ana Maria Sampaio
...
Published in
Glycoconjugate journal
Lectins isolated from Canavalia ensiformis (ConA) and Canavalia brasiliensis (ConBr) are promising molecules to prevent cell death. Acute pancreatitis, characterized by acinar cell necrosis and inflammation, presents significant morbidity and mortality. This study has investigated the effects of ConA and ConBr in experimental acute pancreatitis and...
Loix, Melanie; Wouters, Elien; Vanherle, Sam; Dehairs, Jonas; 65634; McManaman, James L; Kemps, Hannelore; 152345; Swinnen, Johannes; 19636; Haidar, Mansour; Bogie, Jeroen FJ; Hendriks, Jerome JA;
...
Foamy macrophages and microglia containing lipid droplets (LDs) are a pathological hallmark of demyelinating disorders affecting the central nervous system (CNS). We and others showed that excessive accumulation of intracellular lipids drives these phagocytes towards a more inflammatory phenotype, thereby limiting CNS repair. To date, however, the ...
