Characterization of the oat1 gene of Penicillium chrysogenum encoding an ω-aminotransferase: induction by L-lysine, L-or...
Published in Molecular Genetics and Genomics
The Penicillium chrysogenumoat1 gene, which encodes a class III ω-aminotransferase, was cloned and characterized. This enzyme converts lysine into 2-aminoadipic semialdehyde, and plays an important role in the biosynthesis of 2-aminoadipic acid, a precursor of penicillin and other β-lactam antibiotics. The enzyme is related to ornithine-5-aminotran...
