Mitochondrial dynamics: Regulating cell metabolism, homoeostasis, health and disease
éditorial du numéro spécial : Mitochondrial Dynamics / International audience
Varying importance of postzygotic isolation in polyploid speciation? A survey of the triploid block strength, its causal...
The triploid block, primarily caused by endosperm developmental issues, is known as a significant barrier to interploidy hybridization among flowering plants and thereby, polyploid speciation. However, its strength varies across taxa, with some instances of leakiness, questioning its universal role as a barrier. We conducted a literature survey to ...
Gut-liver interaction study on an all-polydimethylsiloxane microfluidic device integrating intestinal paracellular perme...
Microphysiological systems (MPSs) have attracted increasing attention as a method for simulating in vitro drug efficiency. In particular, the interaction between liver and intestine tissues is one of the primary targets since they are closely involved in drug absorption and metabolism. However, most of the intestine-liver MPSs reported previously r...
Large‐scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 chil...
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Only a small number of studies have assessed structural differences between the two hemispheres during childhood and adolescence. However, the existing findings lack consistency or are restricted to a particular brain region, a specific brain feature, or a relatively narrow age range. Here, we investigated associations between brain asymmetry and a...
Thyroid hormone-dependent apoptosis during metamorphosis in Ciona robusta involves both bilaterian-ancestral and vertebr...
Chordate metamorphosis is a postembryonic larva-to-juvenile transition triggered by thyroid hormones and their specific receptors (TR). This crucial developmental event shows a wide morphological diversity among different chordate lineages and is characterized by ecological, morphological, metabolic and behavioral changes that can be drastic. One o...
New COI-COII mtDNA Region Haplotypes in the Endemic Honey Bees Apis mellifera intermissa and Apis mellifera sahariensis ...
The practice of beekeeping in Algeria is of great cultural, social, and economic importance. However, the importation of non-local subspecies reported by beekeepers has disrupted the natural geographical distribution area and the genetic diversity of the native honey bees. To assess the genetic diversity of A. m. intermissa and A. m. sahariensis, a...
THE REVERSION OF MESCS INTO NAÏVE GROUND STATE DOES NOT FOLLOW A LINEAR PATH.
Pluripotent stem cells were established from pre- and post-implantation embryos (ESC and EpiSC respectively). While all can differentiate in vitro into cells representative to the three germ layers, only ESCs can participate to chimeras. Moreover, mouse ESCs initially cultured in media containing serum and leukemia inhibitory factor (S/L) were foun...
Early transcriptional similarities between two distinct neural lineages during ascidian embryogenesis
AbstractIn chordates, the central nervous system arises from precursors that have distinct developmental andtranscriptional trajectories. Anterior nervous systems are ontogenically associated with ectodermallineages while posterior nervous systems are associated with mesoderm. Taking advantage of the welldocumentedcell lineage of ascidian embryos, ...
Notch3 is a genetic modifier of NODAL signalling for patterning asymmetry during mouse heart looping
The TGFβ secreted factor NODAL is a major left determinant required for the asymmetric morphogenesis of visceral organs, including the heart. Yet, when this signalling is absent, shape asymmetry, for example of the embryonic heart loop, is not fully abrogated, indicating that there are other factors regulating left-right patterning. Here, we used a...
Symmetry breaking and fate divergence during lateral inhibition in Drosophila
Lateral inhibition by Notch mediates the adoption of alternative cell fates amongst groups of initially equipotent cells, leading to the formation of regular patterns of cell fates in many tissues across species. Genetic and molecular studies have established a model whereby an intercellular negative feedback loop serves to amplify small stochastic...
