Benichou, Nicolas Lebbah, Saïd Hajage, David Martin-Lefèvre, Laurent Pons, Bertrand Boulet, Eric Boyer, Alexandre Chevrel, Guillaume Lerolle, Nicolas Carpentier, Dorothée
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Published in
Annals of Intensive Care
BackgroundVascular access for renal replacement therapy (RRT) is routine question in the intensive care unit. Randomized trials comparing jugular and femoral sites have shown similar rate of nosocomial events and catheter dysfunction. However, recent prospective observational data on RRT catheters use are scarce. We aimed to assess the site of RRT ...
Andolfo, A. Maatoug, R. Peiffer-Smadja, N. Fayolle, C. Blanckaert, K.
Published in
Antimicrobial Resistance & Infection Control
ContextIn the emergency ward, where the use of ultrasound is common (including for sterile procedures), ward equipment is constantly exposed to high risks of microbiological contamination. There are no clear guidelines for disinfection control practices in emergency departments, and it is not known how emergency ward doctors follow good hygiene pra...
Clé, Marion Constant, Orianne Barthelemy, Jonathan Desmetz, Caroline Martin, Marie France Lapeyre, Lina Cadar, Daniel Savini, Giovanni Teodori, Liana Monaco, Federica
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Published in
Journal of Neuroinflammation
BackgroundUsutu virus (USUV) is an emerging neurotropic arthropod-borne virus recently involved in massive die offs of wild birds predominantly reported in Europe. Although primarily asymptomatic or presenting mild clinical signs, humans infected by USUV can develop neuroinvasive pathologies (including encephalitis and meningoencephalitis). Similar...
Lagou, Vasiliki Mägi, Reedik Hottenga, Jouke- Jan Grallert, Harald Perry, John R. B. Bouatia-Naji, Nabila Marullo, Letizia Rybin, Denis Jansen, Rick Min, Josine L.
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Published in
Nature Communications
Sex differences in fasting glucose and insulin have been identified, but the genetic loci underlying these differences have not. Here, the authors perform a meta-analysis of genome-wide association studies to detect sex-specific and sex-dimorphic loci associated with fasting glucose and insulin.
Nuel, Grégory Garcia, André
Published in
Malaria Journal
BackgroundDespite many technological advances for malaria parasite detection (e.g. high resolution image acquisition), microscopic reading of thick blood smear (TBS) remains the gold standard. Even though available in low technology environment, the microscopy of TBS is slow and time consuming. Moreover microscopy may induce errors at many levels a...
Pistorius, Arthur M. A. Blokker, Ineke
Published in
Genetics Selection Evolution
BackgroundFor many years, breeders of companion animals have applied inbreeding or line breeding to transfer desirable genetic traits from parents to their offspring. Simultaneously, this resulted in a considerable spread of hereditary diseases and phenomena associated with inbreeding depression.ResultsOur cluster analysis of kinship and inbreeding...
Duenk, Pascal Bijma, Piter Wientjes, Yvonne C. J. Calus, Mario P. L.
Published in
Genetics Selection Evolution
BackgroundThe genetic correlation between purebred and crossbred performance (rpc\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${r}_{pc}$$\end{document}) is an importa...
Péré, Hélène Vernet, Raphael Pernot, Simon Pavie, Juliette Robillard, Nicolas Puech, Julien Lameiras, Sonia Lucas, Marie-Laure Nicolas, Alain Badoual, Cécile
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Published in
Scientific Reports
Archival tissue samples collected longitudinally from a patient who died from HPV16-induced high-grade anal intraepithelial squamous cell carcinoma with vertebral HPV16–positive metastasis were retrospectively analyzed by the Capture-HPV method (Capt-HPV) followed by Next-Generation Sequencing (NGS). Full length nucleotide sequences of the same HPV...
Gauvain, Gregory Akolkar, Himanshu Chaffiol, Antoine Arcizet, Fabrice Khoei, Mina A. Desrosiers, Mélissa Jaillard, Céline Caplette, Romain Marre, Olivier Bertin, Stéphane
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Published in
Communications Biology
Gauvain et al demonstrate that optogenetic therapy using the AAV2.7m8- ChR-tdT construct can partially restore vision in non-human primates to levels above those considered legally-blind. This study enables the identification of the most suitable construct for ongoing clinical trials attempting vision restoration in patients with retinitis pigmento...
Yuan, Zehu Sunduimijid, Bolormaa Xiang, Ruidong Behrendt, Ralph Knight, Matthew I. Mason, Brett A. Reich, Coralie M. Prowse-Wilkins, Claire Vander Jagt, Christy J. Chamberlain, Amanda J.
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Published in
Genetics Selection Evolution
BackgroundVariants that regulate transcription, such as expression quantitative trait loci (eQTL), have shown enrichment in genome-wide association studies (GWAS) for mammalian complex traits. However, no study has reported eQTL in sheep, although it is an important agricultural species for which many GWAS of complex meat traits have been conducted...
