Denoncin, Katleen Vertommen, Didier Arts, Isabelle S Goemans, Camille V Rahuel-Clermont, Sophie Messens, Joris Collet, Jean-François
Published in
The Journal of biological chemistry
We report a new function for Escherichia coli DsbC, a protein best known for disulfide bond isomerization in the periplasm. We found that DsbC regulates the redox state of the single cysteine of the L-arabinose-binding protein AraF. This cysteine, which can be oxidized to a sulfenic acid, mediates the formation of a disulfide-linked homodimer under...
Willekens, Jérèmy Hergalant, Sébastien Pourié, Grégory Marin, Fabian Alberto, Jean-Marc Georges, Lucie Paoli, Justine Nemos, Christophe Daval, Jean-Luc Guéant, Jean-Louis
...
Published in
Molecular Neurobiology
Gestational methyl donor (especially B9 and B12 vitamins) deficiency is involved in birth defects and brain development retardation. The underlying molecular mechanisms that are dysregulated still remain poorly understood, in particular in the cerebellum. As evidenced from previous data, females are more affected than males. In this study, we there...
Grieshaber, Scott Grieshaber, Nicole Yang, Hong Baxter, Briana Hackstadt, Ted Omsland, Anders
Published in
Journal of bacteriology
Bacteria of the genus Chlamydia include the significant human pathogens Chlamydia trachomatis and C. pneumoniae All chlamydiae are obligate intracellular parasites that depend on infection of a host cell and transition through a biphasic developmental cycle. Following host cell invasion by the infectious elementary body (EB), the pathogen transitio...
Bouressam, Marie-Lynda Lartaud, Isabelle Dupuis, François Lecat, Sandra
Published in
Naunyn-Schmiedeberg's Archives of Pharmacology
Numerous antibodies targeting G protein-coupled receptors (GPCRs) have been described as non-specific among the polyclonal antibodies against angiotensin II type 1 receptor (AT1). We have tested the newly developed AT1 receptor mouse monoclonal antibody for its specificity. Human embryonic kidney (HEK293) cells, which do not endogenously express AT...
Hassaine, Ghérici Deluz, Cédric Grasso, Luigino Wyss, Romain Hovius, Ruud Stahlberg, Henning Li, Takashi Desmyter, Aline Moreau, Christophe Peclinovska, Lucie
...
There is growing interest in the use of mammalian protein expression systems, and in the use of antibody-derived chaperones, for structural studies. Here, we describe protocols ranging from the production of recombinant membrane proteins in stable inducible cell lines to biophysical characterization of purified membrane proteins in complex with lla...
Manasfi, Youssef Cannesan, Marc-Antoine Riah, Wassila Bressan, Mélanie Laval, Karine Driouich, Azeddine Vicré, Maïté Trinsoutrot-Gattin, Isabelle
Published in
European Journal of Plant Pathology
Phytophthora parasitica infection of Choisya ternata can cause important economical loses due to root rot disease. This research focused on testing the potential benefit of chemical treatment (Mefenoxam) and Biological Control Agents (Glomus intraradices, Gliocladium catenulatum, Trichoderma atroviridae and Bacillus amyloliquefaciens) in protecting...
Ellijimi, Chedli Ben Hammouda, Manel Othman, Houcemeddine Moslah, Wassim Jebali, Jed Mabrouk, Hazem Ben Morjen, Maram Haoues, Meriam Luis, José Marrakchi, Naziha
...
Published in
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Snail secretion is currently revolutionizing the world of cosmetics and human skin care. The efficacy of snail secretion in wounds healing has been proven both in vitro and by clinical studies. However, the potential anti-tumor effect of snail secretion was poorly investigated. In this report, our in vitro study showed that Helix aspersa maxima spe...
Nguyen, Ngoc Thy Vivès, Romain Torres, Magali Delauzun, Vincent Saesen, Els Roig-Zamboni, Veronique Lortat-Jacob, Hugues Rihet, Pascal Bourne, Yves
The HS3ST3A1/B1 genes encode two homologous 3-O-sulfotransferases involved in the late modification step during heparan sulfate (HS) biosynthesis. In addition to the SNPs rs28470223 (C > T) in the promoter region of both HS3ST3A1 and rs62636623 (Gly/Arg) in the stem region of HS3ST3B1, three missense mutations (rs62056073, rs61729712 and rs9906590)...
Nguyen, Ngoc Thy Vivès, Romain Torres, Magali Delauzun, Vincent Saesen, Els Roig-Zamboni, Veronique Lortat-Jacob, Hugues Rihet, Pascal Bourne, Yves
The HS3ST3A1/B1 genes encode two homologous 3-O-sulfotransferases involved in the late modification step during heparan sulfate (HS) biosynthesis. In addition to the SNPs rs28470223 (C > T) in the promoter region of both HS3ST3A1 and rs62636623 (Gly/Arg) in the stem region of HS3ST3B1, three missense mutations (rs62056073, rs61729712 and rs9906590)...
Nguyen, Ngoc Thy Vivès, Romain Torres, Magali Delauzun, Vincent Saesen, Els Roig-Zamboni, Veronique Lortat-Jacob, Hugues Rihet, Pascal Bourne, Yves
The HS3ST3A1/B1 genes encode two homologous 3-O-sulfotransferases involved in the late modification step during heparan sulfate (HS) biosynthesis. In addition to the SNPs rs28470223 (C > T) in the promoter region of both HS3ST3A1 and rs62636623 (Gly/Arg) in the stem region of HS3ST3B1, three missense mutations (rs62056073, rs61729712 and rs9906590)...
