Furber, Matthew J. W. Young, Gregory R. Holt, Giles S. Pyle, Simone Davison, Glen Roberts, Michael G. Roberts, Justin D. Howatson, Glyn Smith, Darren L.
Published in
mSystems
Dietary manipulation with high-protein or high-carbohydrate content are frequently employed during elite athletic training, aiming to enhance athletic performance. Such interventions are likely to impact upon gut microbial content. This study explored the impact of acute high-protein or high-carbohydrate diets on measured endurance performance and ...
Klasek, Scott A. Brock, Marcus T. Calder, W. John Morrison, Hilary G. Weinig, Cynthia Maïgnien, Lois
Published in
mSystems
Microbial communities in the rhizosphere are distinct from those in soils and are influenced by stochastic and deterministic processes during plant development. These communities contain bacteria capable of promoting growth in host plants through various strategies. While some interactions are characterized in mechanistic detail using model systems...
Du, Chao Willemse, Joost Erkelens, Amanda M. Carrion, Victor J. Dame, Remus T. van Wezel, Gilles P.
Published in
mSystems
Bacterial chromosome structure is, to a great extent, organized by a diverse group of proteins collectively referred to as nucleoid-associated proteins (NAPs). Many NAPs have been well studied in Streptomyces, including Lsr2, HupA, HupS, and sIHF. Here, we show that SCO1839 represents a novel family of Actinobacteria NAPs and recognizes a consensus...
Howard, Timothy R. Lum, Krystal K. Kennedy, Michelle A. Cristea, Ileana M.
Published in
mSystems
Human cells identify invading pathogens and activate immune signaling pathways through a wide array of pattern recognition receptors, including DNA sensors. The interferon-inducible protein 16 (IFI16) is a nuclear DNA sensor that recognizes double-stranded DNA from a number of viral sources, including genomes of nuclear-replicating viruses. Among t...
Zhu, Junying Jiang, Xuemei Zhao, Lina Li, Min
Published in
mSystems
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) has been increasingly reported worldwide. Here, we report an outbreak caused by sequence type 859-K19 (ST859-K19) CR-hvKP isolates in a teaching hospital in China. Interestingly, K. pneumoniae ST859 was a single-locus variant of ST11 but has never been reported before. A total of 11...
Li, Fang Jiang, Liuyiqi Pan, Shuming Jiang, Shaowei Fan, Yiwen Jiang, Chao Gao, Chengjin Leng, Yuxin
Published in
mSystems
Emerging evidence shows that modulation of the microbiome can suppress intra-abdominal hypertension (IAH)-induced intestinal barrier damage through the regulation of amino acid (AA) biosynthesis. Here, we investigated the protective effects of orally gavaged Lactobacillus acidophilus L-92 (L92) and a mixture of AA in rats with induced IAH. The resu...
Cantú, Victor J. Salido, Rodolfo A. Huang, Shi Rahman, Gibraan Tsai, Rebecca Valentine, Holly Magallanes, Celestine G. Aigner, Stefan Baer, Nathan A. Barber, Tom
...
Published in
mSystems
Monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on surfaces is emerging as an important tool for identifying past exposure to individuals shedding viral RNA. Our past work demonstrated that SARS-CoV-2 reverse transcription-quantitative PCR (RT-qPCR) signals from surfaces can identify when infected individuals have touched su...
Gilbert, Jack A.
Published in
mSystems
Anderson, Victoria M. Wendt, Karen L. Najar, Fares Z. McCall, Laura-Isobel Cichewicz, Robert H.
Published in
mSystems
Zheng, Hao-Yu Yang, Liang Dong, Tao
Published in
mSystems
The type VI secretion system (T6SS) belongs to the evolutionarily related group of contractile injection systems that employ a contractile outer sheath to inject a rigid spear-like inner tube into target bacterial and eukaryotic cells. The tip of the rigid tube is often decorated by a PAAR-repeat protein as a key structural component. Many members ...
