Song, Wanting Bai, Yi Zhu, Jialin Zeng, Fanxin Yang, Chunmeng Hu, Beibei Sun, Mingjun Li, Chenyan Peng, Shiqiao Chen, Moye
...
Published in
World Journal of Surgical Oncology
BackgroundGastric cancer (GC) represents a major malignancy and is the third deathliest cancer globally. Several lines of evidence indicate that the epithelial-mesenchymal transition (EMT) has a critical function in the development of gastric cancer. Although plentiful molecular biomarkers have been identified, a precise risk model is still necessa...
Nakaya, Seiichi Ogawa, Ryo Hayakawa, Shunsuke Fujihata, Shiro Okubo, Tomotaka Sagawa, Hiroyuki Tanaka, Tatsuya Takahashi, Hiroki Matsuo, Yoichi Takiguchi, Shuji
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Published in
World Journal of Surgical Oncology
BackgroundDespite the established oncological benefits of neoadjuvant chemotherapy for esophageal squamous cell cancer, not all cases demonstrate benefit. Hence, predicting the response to chemotherapy before treatment is desirable. Some reports have shown that immune factors are related to the chemotherapy response. This study aimed to investigate...
Sha, Sha Dong, Jigang Wang, Maoyu Chen, Ziyu Gao, Peng
Published in
World Journal of Surgical Oncology
BackgroundThe radiation-induced lung injury (RILI) in patients with advanced non-small cell lung cancer (NSCLS) is very common in clinical settings; we aimed to evaluate the risk factors of RILI in NSCLS patients, to provide insights into the treatment of NSCLS.MethodsNSCLC patients undergoing three-dimensional conformal radiotherapy (3D-CRT) in ou...
He, Juan Yi, Min Tan, Lingfeng Huang, Jianghua Huang, Lin
Published in
World Journal of Surgical Oncology
BackgroundThe programmed death 1 (PD-1)/programmed death-ligand 1 (PD-L1) have shown positive efficacy in several solid cancers due to their targeted antitumour effects. However, the frequency and clinical implication value in prostate cancer still remain unclear.MethodsThe PD-1/PD-L1 expression was detected by immunohistochemical (IHC) analysis in...
Zhou, Sheng Li Guo, Yan Ping Zhang, Lei Deng, Tao Xu, Zi Guang Ding, Chao Sun, Wen Cong Zhao, Yue Wu Kong, Ling Fei
Published in
World Journal of Surgical Oncology
ObjectiveThe aim of this study was to evaluate the predictive factors of central lymph node metastasis (CLNM) and BRAFV600E mutation in Chinese patients with papillary thyroid carcinoma (PTC).MethodsA total of 943 PTC patients who underwent thyroidectomy from 2014 to 2016 at our hospital were enrolled. Those patients were divided into PTC > 10 mm a...
Wu, Ting Zhang, Zhong-ti Li, Lin Liu, Ru-yue Bei, Bao-ting
Published in
World Journal of Surgical Oncology
ObjectiveThis meta-analysis was implemented to evaluate the association between hypoxia-inducible factor-1α (HIF-1α) C1772T/G1790A polymorphisms and susceptibility to head and neck cancer (HNC).Material and methodsThis meta-analysis has been registered on PROSPERO platform (CRD42021257309). The PubMed, Embase and Web of Science databases were searc...
Sandø, Alina Desiree Fougner, Reidun Grønbech, Jon Erik Bringeland, Erling Audun
Published in
World Journal of Surgical Oncology
BackgroundResponse evaluation following neoadjuvant chemotherapy (NAC) in gastric cancer is debated. The aim of this study was to investigate the value of UICC-downstaging as mode of response evaluation following a MAGIC-style regimen of NAC.MethodsRetrospective, population-based study on consecutive patients with resectable gastric adenocarcinoma ...
Yu, Jie Fan, Qiqi Li, Lingling
Published in
World Journal of Surgical Oncology
BackgroundLong non-coding RNA (lncRNA) MCM3AP-AS1 plays an oncogenic role in several malignancies, but its role in endometrioid carcinoma (EC) is unclear. This study was carried out to explore the role of MCM3AP-AS1 in EC.MethodsA total of 60 EC patients were enrolled in this study. Expression levels of MCM3AP Antisense RNA 1 (MCM3AP-AS1), microRNA...
Jing, Huang Xiuhong, Wu Ying, Yu Zhenrong, Liao Xiyun, Cheng Deping, Luo Changmei, Shen Qi, Wang Tao, Peng Yiyun, Pan
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Published in
World Journal of Surgical Oncology
ObjectiveThis study aimed to evaluate the clinical outcomes for patients with stage IB2/IIA2 cervical squamous cell carcinoma treated with neoadjuvant chemotherapy combined with radical surgery.MethodsA total of 68 patients with cervical squamous cell carcinoma were randomly divided into the experimental group (n = 35) and the control group (n = 33...
Zeng, Ziyang Li, Kang Wang, Xianze Ouyang, Siwen Zhang, Zimu Liu, Zhen Sun, Juan Ye, Xin Kang, Weiming Yu, Jianchun
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Published in
World Journal of Surgical Oncology
BackgroundAn abrupt increase of thyroid cancer has been witnessed paralleling the supplemented iodine intake in formerly iodine-deficient countries. And increased iodine intake has been linked to the rising incidence rate of papillary thyroid cancer (PTC). However, the correlation between iodine and clinicopathological features of PTC has not been ...
