Zhang, Qi Xu, Hai-Feng Song, Wen-Yue Zhang, Peng-Jun Song, Yong-Bo
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND In hepatocellular carcinoma (HCC), abnormal expression of multiple microRNAs (miRNAs) has been shown to be involved in the malignant biological behavior of liver cancer. The vast majority of liver cancer cases in China are closely related to hepatitis B virus (HBV) infection, but there are few studies on the changes of miRNA expression i...
Aggarwal, Himani Sheffield, Kristin M Li, Li Lenis, David Sorg, Rachael Barzi, Afsaneh Miksad, Rebecca
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND Primary tumor location is a prognostic factor for metastatic colorectal cancer (mCRC). Post hoc analyses of mCRC clinical trials, including FIRE-3, CALGB/SWOG 80405, suggest that primary tumor location is also predictive of survival benefit with cetuximab or bevacizumab in combination with 5-fluorouracil-based chemotherapy. AIM Evaluate ...
Zhang, Zhi-Guo Xu, Liang Zhang, Peng-Jun Han, Lei
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND In early gastric cancer (GC), tumor markers are increased in the blood. The levels of these markers have been used as important indexes for GC screening, early diagnosis and prognostic evaluation. However, specific tumor markers have not yet been discovered. Diagnosis based on a single tumor marker has limited significance. The detection...
Sun, Chong-Bing Wang, Hong-Yi Han, Xiao-Qing Liu, Yong-Ning Wang, Meng-Chun Zhang, Hong-Xia Gu, You-Feng Leng, Xiao-Gang
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND Gastric cancer (GC) is one of the most aggressive malignancies, with a high incidence and poor prognosis worldwide. Recently, accumulating evidence has illustrated that long noncoding RNAs (lncRNAs) play pivotal roles in many cancers. It has been reported that LINC00511 contributes to tumorigenesis in various diseases. However, the role ...
Li, Cheng-Gang Zhou, Zhi-Peng Tan, Xiang-Long Zhao, Zhi-Ming
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND Hilar cholangiocarcinoma (HCCA) often produces perineural invasion (PNI) extending to extra-biliary sites, while significant confusion in the incidence of PNI in HCCA has occurred in the literature, and the mechanism of that procedure remains unclear. AIM To summarize the incidence of PNI in HCCA and to provide the distribution of nerve ...
Ye, Shan-Ping Zhu, Wei-Quan Liu, Dong-Ning Lei, Xiong Jiang, Qun-Guang Hu, Hui-Min Tang, Bo He, Peng-Hui Gao, Geng-Mei Tang, He-Chun
...
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND Reports in the field of robotic surgery for rectal cancer are increasing year by year. However, most of these studies enroll patients at a relatively early stage and have small sample sizes. In fact, studies only on patients with locally advanced rectal cancer (LARC) and with relatively large sample sizes are lacking. AIM To investigate ...
Li, Ping Cai, Jia-Xun Han, Fei Wang, Jie Zhou, Jia-Jie Shen, Kai-Wen Wang, Liu-Hua
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND The relationship between microRNAs, such as miR-654-5p and miR-376b-3p, and the prognosis of colon cancer has not been studied until now. AIM To evaluate the expression levels of miR-654-5p and miR-376b-3p and their clinical significance in colon cancer. METHODS RT-qPCR was performed to evaluate miR-654-5p and miR-376b-3p expression in 3...
Song, Bong-Il
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND Lymph node (LN) metastasis is an important prognostic factor in patients with gastric cancer (GC). However, the evaluation of LN metastasis status in the preoperative setting is not accurate. Therefore, precise preoperative prediction of LN metastasis status is crucial for optimal treatment in patients with GC. AIM To develop a preoperat...
Li, Jian-Nan Li, Wei Cao, Lan-Qing Liu, Ning Zhang, Kai
Published in
World Journal of Gastrointestinal Oncology
Mesenchymal stem cells (MSCs), which are a kind of stem cell, possess an immune privileged nature, tumour homing features, and multi-lineage differentiation ability. MSCs have been studied in many fields, such as tissue engineering, nervous system diseases, and cancer treatment. In recent years, an increasing number of researchers have focused on t...
Manzini, Giulia Hapke, Fabius Hines, Ian N Henne-Bruns, Doris Kremer, Michael
Published in
World Journal of Gastrointestinal Oncology
BACKGROUND According to the result of the Cochrane review published in 2012, postoperative adjuvant chemotherapy (CTx) is associated with a survival benefit for rectal cancer patients operated for cure in comparison to patients who underwent only the surgical resection. AIM To analyze the quality of the data supporting the advantage of adjuvant CTx...
