Campos-Murguía, Alejandro Román-Calleja, Berenice M González-Regueiro, José A Hurtado-Díaz-de-León, Ivonne Solís-Ortega, Alberto Adrián Flores-García, Nayelli C García-Juárez, Ignacio Ruiz-Margáin, Astrid Macías-Rodríguez, Ricardo Ulises
Published in
World Journal of Gastroenterology
Metabolic diseases are highly prevalent worldwide and have been associated with adverse clinical outcomes, including mortality, in patients developing coronavirus disease (COVID-19). Because of the close relationship between metabolic diseases such as type 2 diabetes mellitus and obesity and the presence of metabolic-associated fatty liver disease ...
Chu, Zi-Qiang Zhang, Ke-Cheng Chen, Lin
Published in
World Journal of Gastroenterology
Gastrointestinal (GI) cancer is a high-risk malignancy and is characterized by high mortality and morbidity worldwide. Neutrophil extracellular traps (NETs), a weblike structure consisting of chromatin DNA with interspersed cytoplasmic and granule proteins, are extruded by activated neutrophils to entrap and kill bacteria and fungi. However, accumu...
Wang, Huanhuan Esemu-Ezewu, Paul Pan, Jingyi Ivanovska, Julijana Gauda, Estelle B Belik, Jaques
Published in
World Journal of Gastroenterology
BACKGROUND Oral intake is dependent on the gastric ability to accommodate the food bolus. Comparatively, neonates have a smaller gastric capacity than adults and this may limit the volume of their milk intake. Yet, we previously reported that the newborn rat gastric milk volume is greatest after birth and, when normalized to body weight, decreases ...
Milosevic, Ivana Russo, Edda Vujovic, Ankica Barac, Aleksandra Stevanovic, Olja Gitto, Stefano Amedei, Amedeo
Published in
World Journal of Gastroenterology
Changes in gut microbiota influence both the gut and liver, which are strictly connected by the so-called “gut–liver axis”. The gut microbiota acts as a major determinant of this relationship in the onset and clinical course of liver diseases. According to the results of several studies, gut dysbiosis is linked to viral hepatitis, mainly hepatitis ...
Hagiwara, Hiroaki Moki, Fumitaka Yamashita, Yukiko Saji, Kazuki Iesaki, Keigo Suda, Hiromitsu
Published in
World Journal of Gastroenterology
BACKGROUND Despite its decreased incidence in Japan, gastric cancer continues among the leading causes of cancer-related deaths in both men and women. Accordingly, efforts are still required to lower the mortality rate of gastric cancer in Japan. Maebashi City introduced endoscopic gastric cancer screening in 2004, and participants are able to choo...
White, Brian Sterrett, John D Grigoryan, Zoya Lally, Lauren Heinze, Jared D Alikhan, Hyder Lowry, Christopher A Perez, Lark J DeSipio, Joshua Phadtare, Sangita
...
Published in
World Journal of Gastroenterology
BACKGROUND Helicobacter pylori ( H. pylori ) , a bacterium that infects approximately half of the world’s population, is associated with various gastrointestinal diseases, including peptic ulcers, non-ulcer dyspepsia, gastric adenocarcinoma, and gastric lymphoma. As the burden of antibiotic resistance increases, the need for new adjunct therapies d...
Wei, Yan-Xia Zheng, Kui-Yang Wang, Yu-Gang
Published in
World Journal of Gastroenterology
A significant breakthrough in the field of obesity research was the demonstration that an obese phenotype could be manipulated by modulating the gut microbiota. An important next step is to elucidate a human-relevant “map’’ of microbiota-host interactions that regulate the metabolic health of the host. An improved understanding of this crosstalk is...
Demirtas, Coskun Ozer Brunetto, Maurizia Rossana
Published in
World Journal of Gastroenterology
Surveillance with abdominal ultrasound with or without alpha-fetoprotein is recommended by clinical practice guidelines for patients who are considered to be at risk of developing hepatocellular carcinoma (HCC), including those with cirrhosis, advanced fibrosis and special subgroups of chronic hepatitis B (CHB). Application of the standard surveill...
Garg, Pankaj Kaur, Baljit Yagnik, Vipul D Dawka, Sushil Menon, Geetha R
Published in
World Journal of Gastroenterology
Magnetic resonance imaging (MRI) is considered the gold standard for the evaluation of anal fistulas. There is sufficient literature available outlining the interpretation of fistula MRI before performing surgery. However, the interpretation of MRI becomes quite challenging in the postoperative period after the surgery of fistula has been undertake...
Li, Mou Jin, Yu-Mei Zhang, Yong-Chang Zhao, Ya-Li Huang, Chen-Cui Liu, Sheng-Mei Song, Bin
Published in
World Journal of Gastroenterology
BACKGROUND Perineural invasion (PNI), as a key pathological feature of tumor spread, has emerged as an independent prognostic factor in patients with rectal cancer (RC). The preoperative stratification of RC patients according to PNI status is beneficial for individualized treatment and improved prognosis. However, the preoperative evaluation of PN...
