Demirli Atici, Semra Kamer, Erdinc
Published in
World Journal of Gastroenterology
Evaluation of response to chemotherapy in colorectal cancer patients with synchronous liver metastases is important in terms of treatment management. In this Letter to the Editor, several issues in the article are discussed. For the comparison of carbohydrate antigen 19-9 (CA19-9) values referenced in the study, the patient group was not matched fo...
Hillestad, Eline Margrete Randulff van der Meeren, Aina Nagaraja, Bharat Halandur Bjørsvik, Ben René Haleem, Noman Benitez-Paez, Alfonso Sanz, Yolanda Hausken, Trygve Lied, Gülen Arslan Lundervold, Arvid
...
Published in
World Journal of Gastroenterology
Irritable bowel syndrome (IBS) is a common clinical label for medically unexplained gastrointestinal symptoms, recently described as a disturbance of the microbiota-gut-brain axis. Despite decades of research, the pathophysiology of this highly heterogeneous disorder remains elusive. However, a dramatic change in the understanding of the underlying...
Xiao, Fang Wang, Hong-Wu Hu, Jun-Jian Tao, Ran Weng, Xin-Xin Wang, Peng Wu, Di Wang, Xiao-Jing Yan, Wei-Ming Xi, Dong
...
Published in
World Journal of Gastroenterology
BACKGROUND Heterogeneous macrophages play an important role in multiple liver diseases, including viral fulminant hepatitis (VFH). Fibrinogen-like protein 2 (FGL2) is expressed on macrophages and regulates VFH pathogenesis; however, the underlying mechanism remains unclear. AIM To explore how FGL2 regulates macrophage function and subsequent liver ...
Hu, Dong-Xin Sun, Qi-Feng Xu, Lin Lu, Hong-Da Zhang, Fan Li, Zhen-Miao Zhang, Ming-Yan
Published in
World Journal of Gastroenterology
BACKGROUND Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent malignancies that seriously threaten people’s health worldwide. DEAD-box helicase 51 (DDX51) is a member of the DEAD-box (DDX) RNA helicase family, and drives or inhibits tumor progression in multiple cancer types. AIM To determine whether DDX51 affects the biological...
Ranković, Ivan Milivojević, Vladimir Pavlović Marković, Aleksandra Bezmarević, Mihailo
Published in
World Journal of Gastroenterology
Elaboration of carotid atherosclerosis in the setting of hepatitis B virus (HBV) infection should emphasize the significance of extrahepatic manifestations of the infection pathogenesis. Diverse processes comprise the pathoevolution of HBV infection, rendering it a multi-systemic disease in its essence. Our work not only exemplified atherosclerosis...
Perisetti, Abhilash Goyal, Hemant Yendala, Rachana Chandan, Saurabh Tharian, Benjamin Thandassery, Ragesh Babu
Published in
World Journal of Gastroenterology
Liver cancer is the second most occurring cancer worldwide and is one of the leading causes of cancer-related deaths. Hepatocellular carcinoma (HCC) is the most common (80%-90%) type among malignant liver cancers. Sarcopenia occurs very early in HCC and can predict and provide an opportunity to improve muscle health before engaging in the treatment...
Araújo, Glauber Rocha Lima Marques, Hanna Santos Santos, Maria Luísa Cordeiro da Silva, Filipe Antônio França da Brito, Breno Bittencourt Correa Santos, Gabriel Lima de Melo, Fabrício Freire
Published in
World Journal of Gastroenterology
The inflammatory pattern during Helicobacter pylori ( H. pylori ) infection is changeable and complex. During childhood, it is possible to observe a predominantly regulatory response, evidenced by high concentrations of key cytokines for the maintenance of Treg responses such as TGF-β1 and IL-10, in addition to high expression of the transcription ...
Gnodi, Elisa Meneveri, Raffaella Barisani, Donatella
Published in
World Journal of Gastroenterology
Celiac disease (CeD) is a multifactorial autoimmune disorder spread worldwide. The exposure to gluten, a protein found in cereals like wheat, barley and rye, is the main environmental factor involved in its pathogenesis. Even if the genetic predisposition represented by HLA-DQ2 or HLA-DQ8 haplotypes is widely recognised as mandatory for CeD develop...
Chrysavgis, Lampros Giannakodimos, Ilias Diamantopoulou, Panagiota Cholongitas, Evangelos
Published in
World Journal of Gastroenterology
Non-alcoholic fatty liver disease (NAFLD) has emerged as the most common liver disorder worldwide mainly attributed to the epidemic spread of obesity and type 2 diabetes mellitus. Although it is considered a benign disease, NAFLD can progress to non-alcoholic steatohepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). Most data regarding t...
Sintusek, Palittiya Thanapirom, Kessarin Komolmit, Piyawat Poovorawan, Yong
Published in
World Journal of Gastroenterology
Viral hepatitis infections are a great burden in children who have received liver transplant. Hepatotropic viruses can cause liver inflammation that can develop into liver graft fibrosis and cirrhosis over the long term. Immunological reactions due to viral hepatitis infections are associated with or can mimic graft rejection, rendering the conditi...
