Zhang, Jian Liu, Zhichao Zhang, Yuanhang Geng, Feng Wang, Shengfei Fan, Fei Zhang, Qinghua Xu, Qiao
Published in
Micromachines
Silicon carbide (SiC) ceramics are widely used as structural materials for various applications. However, the extraordinarily high hardness, brittleness, low material removal rate, and severe tool wear of these materials significantly impact the performance of conventional mechanical processing techniques. In this study, we investigated the influen...
Kluz, Tomasz Bogaczyk, Anna Wita-Popów, Barbara Habało, Piotr Kluz-Barłowska, Marta
Published in
Medicina (Kaunas, Lithuania)
Giant ovarian tumors are rare, as most cases are diagnosed during routine gynecological check-ups or abdominal ultrasound examinations. They are a challenge for gynecologists and surgeons. Diagnosis in such patients is difficult due to the limitations of the medical apparatus. Perioperative management requires specialized anesthetic medical care an...
Gunduz, Ozgur Sapmaz-Metin, Melike Topuz, Ruhan Deniz Kaya, Oktay Karadag, Cetin Hakan Ulugol, Ahmet
Published in
Medicina (Kaunas, Lithuania)
Background and Objectives: Allergic contact dermatitis is a common type IV hypersensitivity reaction characterised by redness, itching, oedema and thickening of the skin. It occurs in about 7% of the population and its incidence is increasing. It has been observed that the preconditioning of tissues by exposing them to transient ischemia increases ...
Sreekumar, Parameswaran Gangadharan Su, Feng Spee, Christine Hong, Elise Komirisetty, Ravikiran Araujo, Eduardo Nusinowitz, Steven Reddy, Srinivasa T Kannan, Ram
Published in
Antioxidants (Basel, Switzerland)
Although AMD is a complex disease, oxidative stress is a crucial contributor to its development, especially in view of the higher oxygen demand of the retina. Paraoxonase 2 (PON2) is a ubiquitously and constitutively expressed antioxidant protein that is found intracellularly associated with mitochondrial membranes and modulates mitochondrial ROS p...
Miranda, Ana Luísa Soares de Antunes, Bruno Cesar Minozzo, João Carlos Lima, Sabrina de Almeida Botelho, Ana Flávia Machado Campos, Marco Túlio Gomes Chávez-Olórtegui, Carlos Soto-Blanco, Benito
Published in
Toxins
Antivenom production against Loxosceles venom relies on horses being immunized and bled for plasma harvest. One horse can partake in several cycles of antivenom production, which will require years of constant venom and adjuvant inoculation and bleeding. The actual impact on the health of horses that participate in several antivenom-producing cycle...
Chen, Xiaoke Xie, Kejia Sun, Xinzheng Zhang, Chengzhu He, Hui
Published in
International journal of environmental research and public health
(1) Background: The declined function of peripheral circulating endothelial progenitor cells (EPCs) in aging individuals resulted in decreased endothelial cell regeneration and vascular endothelial function. Improving EPCs function in aging individuals plays an important role in preventing cardiovascular diseases. (2) Methods: Thirty aged (18-month...
Lee, Chung-Pei Chen, Mei-Ru
Published in
Viruses
The nuclear envelope (NE) of eukaryotic cells has a highly structural architecture, comprising double lipid-bilayer membranes, nuclear pore complexes, and an underlying nuclear lamina network. The NE structure is held in place through the membrane-bound LINC (linker of nucleoskeleton and cytoskeleton) complex, spanning the inner and outer nuclear m...
Rogers, Jeffrey M Iudicello, Jennifer E Marcondes, Maria Cecilia G Morgan, Erin E Cherner, Mariana Ellis, Ronald J Letendre, Scott L Heaton, Robert K Grant, Igor
Published in
Viruses
Methamphetamine and cannabis are two widely used substances among people living with HIV (PLWH). Whereas methamphetamine use has been found to worsen HIV-associated neurocognitive impairment, the effects of combined cannabis and methamphetamine use disorder on neurocognition in PLWH are not understood. In the present study, we aimed to determine th...
Hammond, Edward Haynes, Nicole M. Cullinane, Carleen Brennan, Todd V. Bampton, Darryn Handley, Paul Karoli, Tomislav Lanksheer, Fleur Lin, Liwen Yang, Yiping
...
Published in
Journal for ImmunoTherapy of Cancer
BackgroundPixatimod (PG545) is a novel clinical-stage immunomodulatory agent capable of inhibiting the infiltration of tumor-associated macrophages (TAMs) yet also stimulate dendritic cells (DCs), leading to activation of natural killer (NK) cells. Preclinically, pixatimod inhibits heparanase (HPSE) which may be associated with its inhibitory effec...
Moga, Radu Andrei Olteanu, Cristian Doru Botez, Mircea Buru, Stefan Marius
Published in
International journal of environmental research and public health
This study examines 0.6 N-4.8 N as the maximum orthodontic force to be applied to dental pulp and apical NVB on intact and 1-8 mm reduced periodontal-ligament (PDL), in connection with movement and ischemic, necrotic and resorptive risk. In addition, it examines whether the Tresca finite-element-analysis (FEA) criterion is more adequate for the exa...