Rondinone, Valeria Pace, Lorenzo Fasanella, Antonio Manzulli, Viviana Parisi, Antonio Capobianchi, Maria Rosaria Ostuni, Angelo Chironna, Maria Caprioli, Elisabetta Labonia, Maria
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Published in
Viruses
The coronavirus disease 2019 (Covid-19) pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and presents a global health emergency that needs urgent intervention. Viruses constantly change through mutation, and new variants of a virus are expected to occur over time. In the United Kingdom (UK), a new variant calle...
Westman, Mark Norris, Jacqueline Malik, Richard Hofmann-Lehmann, Regina Parr, Yasmin A Armstrong, Emma McDonald, Mike Hall, Evelyn Sheehy, Paul Hosie, Margaret J
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Published in
Viruses
A field study undertaken in Australia compared the antibody responses induced in client-owned cats that had been vaccinated using two inactivated whole feline leukaemia virus (FeLV) vaccines, the monovalent vaccine Fel-O-Vax® Lv-K and the polyvalent vaccine Fel-O-Vax® 5. Serum samples from 428 FeLV-uninfected cats (118 FeLV-vaccinated and 310 FeLV-...
Fada, Behdokht Jan Reward, Eleazar Gu, Haidong
Published in
Viruses
Nuclear domains 10 (ND10), a.k.a. promyelocytic leukemia nuclear bodies (PML-NBs), are membraneless subnuclear domains that are highly dynamic in their protein composition in response to cellular cues. They are known to be involved in many key cellular processes including DNA damage response, transcription regulation, apoptosis, oncogenesis, and an...
Deschler, Sebastian Kager, Juliane Erber, Johanna Fricke, Lisa Koyumdzhieva, Plamena Georgieva, Alexandra Lahmer, Tobias Wiessner, Johannes R Voit, Florian Schneider, Jochen
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Published in
Viruses
Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), comprises mild courses of disease as well as progression to severe disease, characterised by lung and other organ failure. The immune system is considered to play a crucial role for the pathogenesis of COVID-19, although espec...
Arnaboldi, Sara Righi, Francesco Filipello, Virginia Trogu, Tiziana Lelli, Davide Bianchi, Alessandro Bonardi, Silvia Pavoni, Enrico Bertasi, Barbara Lavazza, Antonio
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Published in
Viruses
Mammalian orthoreoviruses (MRVs) are emerging infectious agents that may affect wild animals. MRVs are usually associated with asymptomatic or mild respiratory and enteric infections. However, severe clinical manifestations have been occasionally reported in human and animal hosts. An insight into their circulation is essential to minimize the risk...
Shin, Hye Jin Ku, Keun Bon Kim, Soojin Kim, Heon Seok Kim, Yeon-Soo Kim, Bum-Tae Kim, Seong-Jun Kim, Chonsaeng
Published in
Viruses
Genetic screens using CRISPR/Cas9 have been exploited to discover host-virus interactions. These screens have identified viral dependencies on host proteins during their life cycle and potential antiviral strategies. The acyl-CoA binding domain containing 3 (ACBD3) was identified as an essential host factor for the Coxsackievirus B3 (CVB3) infectio...
Rossouw, Esmari Brauer, Marieke Meyer, Pieter du Plessis, Nicolette M Avenant, Theunis Mans, Janet
Published in
Viruses
Viral gastroenteritis remains a major cause of hospitalisation in young children. This study aimed to determine the distribution and diversity of enteric viruses in children ≤5 years, hospitalised with gastroenteritis at Kalafong Provincial Tertiary Hospital, Pretoria, South Africa, between July 2016 and December 2017. Stool specimens (n = 205) wer...
Würzner, Reinhard
Published in
Viruses
Salpini, Romina Piermatteo, Lorenzo Battisti, Arianna Colagrossi, Luna Aragri, Marianna Yu La Rosa, Katia Bertoli, Ada Saccomandi, Patrizia Lichtner, Miriam Marignani, Massimo
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Published in
Viruses
Immune-suppression driven Hepatitis B Virus (HBV)-reactivation poses serious concerns since it occurs in several clinical settings and can result in severe forms of hepatitis. Previous studies showed that HBV strains, circulating in patients with HBV-reactivation, are characterized by an enrichment of immune-escape mutations in HBV surface antigen ...
Chertow, Daniel S Shekhtman, Louis Lurie, Yoav Davey, Richard T Heller, Theo Dahari, Harel
Published in
Viruses
Mathematical modeling of Ebola virus (EBOV)-host dynamics during infection and treatment in vivo is in its infancy due to few studies with frequent viral kinetic data, lack of approved antiviral therapies, and limited insight into the timing of EBOV infection of cells and tissues throughout the body. Current in-host mathematical models simplify EBO...