McIlwain, David R. Chen, Han Apkarian, Maria Affrime, Melton Bock, Bonnie Kim, Kenneth Mukherjee, Nilanjan Nolan, Garry P. McNeal, Monica M.
Published in
Virology Journal
Background Influenza places a significant burden on global health and economics. Individual case management and public health efforts to mitigate the spread of influenza are both strongly impacted by our ability to accurately and efficiently detect influenza viruses in clinical samples. Therefore, it is important to understand the performance chara...
Wei, Qiang Bai, Yilin Song, Yapeng Liu, Yunchao Yu, Wei Sun, Yaning Wang, Li Deng, Ruiguang Xing, Guangxu Zhang, Gaiping
...
Published in
Virology Journal
Classical swine fever (CSF) caused by the classical swine fever virus (CSFV) is a highly contagious swine disease resulting in large economical losses worldwide. The viral envelope glycoprotein E2 and Erns are major targets for eliciting antibodies against CSFV in infected animals. In this report, the glycoprotein E2 and Erns were expressed using t...
Zhao, Kuangjie Yin, Yueyan Hua, Mengying Wang, Shaoxiang Mo, Xiaohan Yuan, Enping Zheng, Hongying Lin, Lin Chen, Hairu Lu, Yuwen
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Published in
Virology Journal
Pepper vein yellows viruses (PeVYV) are phloem-restricted viruses in the genus Polerovirus , family Luteoviridae . Typical viral symptoms of PeVYV including interveinal yellowing of leaves and upward leaf curling were observed in pod pepper plants ( Capsicum frutescens ) growing in Wenshan city, Yunnan province, China. The complete genome sequence ...
Wang, Chao Wei, Tianli Ma, Fenlian Wang, Hao Guo, Jianqiang Chen, Aijun Huang, Yiman Xie, Zhiping Zheng, Lishu
Published in
Virology Journal
Background Acute respiratory tract infections (ARTIs) causes high amounts of morbidity and mortality worldwide every year. Human metapneumovirus (HMPV) is a major pathogen of ARTIs in children. In this study, we aimed to investigate the epidemiology and genotypic diversity of HMPV in children hospitalized with ARTIs in Beijing, China. Methods Hospi...
Freire‑Paspuel, Byron Garcia‑Bereguiain, Miguel Angel
Published in
Virology Journal
Yang, Yuting Zhang, Yun Yang, Changcheng Fang, Fang Wang, Ying Chang, Haiyan Chen, Ze Chen, Ping
Published in
Virology Journal
Background Both the highly pathogenic avian influenza (HPAI) H5N1 and low pathogenic avian influenza (LPAI) H9N2 viruses have been reported to cross species barriers to infect humans. H5N1 viruses can cause severe damage and are associated with a high mortality rate, but H9N2 viruses do not cause such outcomes. Our purpose was to use proteomics tec...
Zheng, Yi Zhao, Youyun Wang, Yefu Rao, Jun
Published in
Virology Journal
Background In recent years, fluorescent quantitative polymerase chain reaction assays for detecting viral DNA are in widespread use throughout the world. However, considering the wide distribution of new herpesvirus among the population, we constructed a method to detect HHV-6, 7, and 8 simultaneously. Methods The blood samples of 74 blood donors a...
Lan, Tingyu Wei, Zhiqiang He, Yulin Wan, Song Liu, Li Cheng, Bin Li, Ruimin Chen, Hongxia Liu, Guohua Meng, Zhongji
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Published in
Virology Journal
Background Hepatitis B virus (HBV) infection is difficult to cure. HBV-specific immune tolerance plays a key role in HBV persistence, and enhancing cellular and humoral immunity will improve the control of HBV infection. The purpose of the study was to explore the anti-HBV and immunostimulatory effects of msiRNAs that introduce unpaired uridine bul...
Li, Xiuli Gu, Min Zheng, Qinmei Gao, Ruyi Liu, Xiufan
Published in
Virology Journal
Influenza A virus (IAV) contains a genome with eight single-stranded, negative-sense RNA segments that encode 17 proteins. During its assembly, all eight separate viral RNA (vRNA) segments are incorporated into virions in a selective manner. Evidence suggested that the highly selective genome packaging mechanism relies on RNA-RNA or protein-RNA int...
Long, Samuel Berkemeier, Brian
Published in
Virology Journal
Background Simian immunodeficiency virus (SIV)-infected rhesus macaques constitute an excellent model of human HIV infection. Sensitive detection of SIV RNA in cell and tissue samples from infected animals subjected to treatment regimens becomes especially critical in determining which therapeutic attempts are successful, and consequently, which in...