Sauvestre, Fanny Belleannée, Geneviève Bréal, Claire Mohr, Catherine Fong, Harold IpKan Cossin, Sébastien Tabrizi, Reza Milpied, Noël Vigouroux, Stéphane Goussot, Jean-François
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Published in
Virchows Archiv : an international journal of pathology
Gastrointestinal (GI) graft-versus-host-disease (GVHD) is a common and severe complication of allogeneic hematopoietic stem cell transplantation, but clinical and histological features are unspecific. The aim of this study was to correlate the histological GI GVHD grade with the clinical outcomes. In a retrospective study of 112 patients with clini...
Patil, Deepa T Odze, Robert D
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Virchows Archiv : an international journal of pathology
Certain types of colitides, such as collagenous colitis, lymphocytic colitis, and ischemic colitis, have distinct histologic features that allow for a specific diagnosis. However, in most colonic biopsy specimens, a definite diagnosis cannot be established on the basis of histology alone. Thus, in most cases of colitis, it is helpful to utilize a s...
Gorkiewicz, Gregor Moschen, Alexander
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Virchows Archiv : an international journal of pathology
The gastrointestinal (GI) tract harbors a diverse and host-specific gut microbial community. Whereas host-microbe interactions are based on homeostasis and mutualism, the microbiome also contributes to disease development. In this review, we summarize recent findings connecting the GI microbiome with GI disease. Starting with a description of bioch...
Cerbelli, Bruna Pisano, Annalinda Colafrancesco, Serena Pignataro, Maria Gemma Biffoni, Marco Berni, Silvia De Luca, Antonia Riccieri, Valeria Priori, Roberta Valesini, Guido
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Virchows Archiv : an international journal of pathology
Anti-synthetase syndrome is an autoimmune disease characterized by autoantibodies toward amino acyl-tRNA synthetases (ARS), anti-Jo 1 being the most commonly detected. Muscle damage develops in up to 90% of ARS-positive patients, characterized by a necrotizing myositis restricted to the perifascicular region. This topographic distribution of muscle...
Saglam, Arzu Balaban, Seda Yıldırım, Tolga Erdem, Yunus Uner, Aysegul Büyükaşık, Yahya
Published in
Virchows Archiv : an international journal of pathology
Moon, Andres Smith, Geoffrey H Kong, Jun Rogers, Thomas E Ellis, Carla L Farris, Alton B Brad 3rd
Published in
Virchows Archiv : an international journal of pathology
Renal allograft rejection diagnosis depends on assessment of parameters such as interstitial inflammation; however, studies have shown interobserver variability regarding interstitial inflammation assessment. Since automated image analysis quantitation can be reproducible, we devised customized analysis methods for CD3+ T-cell staining density as a...
Lambein, Kathleen Van Bockstal, Mieke Vandemaele, Lies Van den Broecke, Rudy Cocquyt, Veronique Geenen, Sofie Denys, Hannelore Libbrecht, Louis
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Virchows Archiv : an international journal of pathology
Although the prognostic and predictive significance of human epidermal growth factor receptor 2 (HER2) in invasive breast cancer is well established, its role in ductal carcinoma in situ (DCIS) remains unclear. Reports on combined evaluation of both HER2 protein expression and HER2 amplification status in pure DCIS and DCIS adjacent to invasive duc...
Teunissen, B T Knuiman, G J Eijkelenboom, A Wauters, C A P Wouda, S Blokx, W A M
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Virchows Archiv : an international journal of pathology
Guyard, Alice Boyez, Alice Pujals, Anaïs Robe, Cyrielle Tran Van Nhieu, Jeanne Allory, Yves Moroch, Julien Georges, Odette Fournet, Jean-Christophe Zafrani, Elie-Serge
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Virchows Archiv : an international journal of pathology
Formalin-fixed paraffin-embedded (FFPE) tissue blocks are widely used to identify clinically actionable molecular alterations or perform retrospective molecular studies. Our goal was to quantify degradation of DNA occurring during mid to long-term storage of samples in usual conditions. We selected 46 FFPE samples of surgically resected carcinomas ...
Vanoli, Alessandro Di Sabatino, Antonio Martino, Michele Dallera, Elena Furlan, Daniela Mescoli, Claudia Macciomei, Maria Cristina Biancone, Livia Neri, Benedetto Grillo, Federica
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Virchows Archiv : an international journal of pathology
