Carretero-Barrio, Irene Lop-Gros, Joan Iglesias, Mar Martínez, Carolina Matias-Guiu, Xavier Pérez-Mies, Belén Palacios, José
Published in
Virchows Archiv : an international journal of pathology
This study aimed to assess the impact of the COVID-19 pandemic on the training of Spanish pathology residents by conducting an online survey. It was distributed among the pathologists who had been residents during the pandemic and consisted of 31 questions about the demographics and the impact of the pandemic on their pathology training. In total, ...
Mattiolo, Paola Mafficini, Andrea Lawlor, Rita T Marchegiani, Giovanni Malleo, Giuseppe Pea, Antonio Salvia, Roberto Piccoli, Paola Sciammarella, Concetta Santonicco, Nicola
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Published in
Virchows Archiv : an international journal of pathology
Hepatoid tumors (HTs) represent a rare group of neoplasms that are histologically similar to hepatocellular carcinoma but arise outside the liver. The current World Health Organization classification recognizes the hepatoid morphology of pancreatic tumors only as a possible variant of pancreatic ductal adenocarcinoma (PDAC). Here, we describe two c...
Shinohara, Shizu Bychkov, Andrey Munkhdelger, Jijgee Kuroda, Kishio Yoon, Han-Seung Fujimura, Shota Tabata, Kazuhiro Furusato, Bungo Niino, Daisuke Morimoto, Shinpei
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Virchows Archiv
Consultation by subspecialty experts is the most common mode of rendering diagnosis in challenging cases in pathological practice. Our study aimed to highlight the diagnostic benefits of whole-slide image (WSI)-based remote consultation. We obtained diagnostically challenging cases from two institutions from the years 2010 and 2013, with histologic...
Hladek, Luca Bankov, Katrin von der Grün, Jens Filmann, Natalie Demes, Melanie Vallo, Stefan Wild, Peter J Winkelmann, Ria
Published in
Virchows Archiv : an international journal of pathology
Penile squamous cell carcinomas are rare tumor entities throughout Europe. Early lymphonodal spread urges for aggressive therapeutic approaches in advanced tumor stages. Therefore, understanding tumor biology and its microenvironment and correlation with known survival data is of substantial interest in order to establish treatment strategies adapt...
Lerch, Julia M Pai, Rish K Brown, Ian Gill, Anthony J Jain, Dhanpat Kővári, Bence Kushima, Ryoji Sheahan, Kieran Slavik, Tomas Srivastava, Amitabh
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Published in
Virchows Archiv : an international journal of pathology
The extent of gastric intestinal metaplasia (GIM) can be used to determine the risk of gastric cancer. Eleven international gastrointestinal expert pathologists estimated the extent of GIM on haematoxylin and eosin (H&E)- and Alcian blue-Periodic acid Schiff (AB-PAS)-stained slides of 46 antrum biopsies in 5% increments. Interobserver agreement was...
Seyrek, Neslisah Hollemans, Eva Andrinopoulou, Eleni-Rosalina Osanto, Susanne Pelger, Rob C M van der Poel, Henk G Bekers, Elise Remmers, Sebastiaan Schoots, Ivo G van Leenders, Geert J L H
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Published in
Virchows Archiv : an international journal of pathology
Percentage Gleason pattern 4, invasive cribriform and/or intraductal carcinoma (IC/IDC) and minor pattern 5 are recognized as independent parameters for prostate cancer outcome, but are not incorporated in current grade groups (GGs). Two proof-of-principle studies have proposed alternative grading schemes based on percentage Gleason pattern 4/5 (in...
Santi, Raffaella Ballestriero, Roberta Canzonieri, Vincenzo Gulcznsky, Jacek de Gouveia, Rosa Henriques Ariza, Aurelio Carvalho, Lina Nesi, Gabriella
Published in
Virchows Archiv : an international journal of pathology
While keeping their original purpose of training medical students, pathology museums hold great biological value, offering unique specimens for scientific research through modern radiological, pathological and biomolecular techniques. Moreover, the artefacts, models and drawings displayed in these museums are a precious cultural and artistic herita...
Agaimy, Abbas Meidenbauer, Norbert Sukov, William R Stoehr, Robert Vieth, Michael Roemer, Frank Grützmann, Robert Folpe, Andrew L
Published in
Virchows Archiv : an international journal of pathology
Pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts and hemosiderotic fibrolipomatous tumor (HFLT) are two rare low-grade locally recurring neoplasms with predilection for the foot/ankle. Recent studies support a close link between the two entities, and origin of PHAT from HFLT and occurrence of hybrid HFLT/PHAT have been documented. Bot...
Vasella, Mauro Wagner, Ulrich Fritz, Christine Seidl, Kati Giudici, Luca Exner, Gerhard Ulrich Moch, Holger Wild, Peter Johannes Bode-Lesniewska, Beata
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Virchows Archiv : an international journal of pathology
BCOR-rearranged sarcomas are rare and belong to the Ewing-like sarcomas (ELS). Their morphology and histopathological features make the diagnosis challenging. We present a case, initially diagnosed as an unusual extraskeletal myxoid chondrosarcoma (EMC). A 54-year-old male patient developed an asymptomatic swelling of the lower leg. Imaging showed ...
Yamashita, Hironori Tourna, Aikaterini Akita, Masayuki Itoh, Tomoo Chokshi, Shilpa Ajiki, Tetsuo Fukumoto, Takumi Youngson, Neil A Zen, Yoh
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Virchows Archiv : an international journal of pathology
Mutations in IDH1/2 and the epigenetic silencing of TET2 occur in leukaemia or glioma in a mutually exclusive manner. Although intrahepatic cholangiocarcinoma (iCCA) may harbour IDH1/2 mutations, the contribution of TET2 to carcinogenesis remains unknown. In the present study, the expression and promoter methylation of TET2 were investigated in iCC...