Pronethalol decreases RBPJκ to reduce Sox2 in cerebral arteriovenous malformation.
Published in Vascular medicine (London, England)
Bleeding, death, and costs of care during hospitalization for acute pulmonary embolism: Insights from the Saint Luke's O...
Published in Vascular medicine (London, England)
Limited data exist that comprehensively describe the practical management, in-hospital outcomes, healthcare resource utilization, and rates of post-hospital readmission among patients with submassive and massive pulmonary embolism (PE). Consecutive discharges for acute PE were identified from a single health system over 3 years. Records were audite...
Clinical presentation and outcomes of patients with isolated subsegmental pulmonary embolism: A tertiary care center exp...
...Published in Vascular medicine (London, England)
COVID-19-associated coagulopathy: An exploration of mechanisms.
Published in Vascular medicine (London, England)
An ongoing global pandemic of viral pneumonia (coronavirus disease [COVID-19]), due to the virus SARS-CoV-2, has infected millions of people and remains a threat to many more. Most critically ill patients have respiratory failure and there is an international effort to understand mechanisms and predictors of disease severity. Coagulopathy, characte...
Temporal trends in pharmacologic prophylaxis for venous thromboembolism after hip and knee replacement in older adults.
...Published in Vascular medicine (London, England)
Trends in prescription for venous thromboembolism (VTE) prophylaxis following total hip (THR) and knee replacement (TKR) since the approval of direct oral anticoagulants (DOACs) and the 2012 guideline endorsement of aspirin are unknown, as are the risks of adverse events. We examined practice patterns in the prescription of prophylaxis agents and t...
Endothelium function dependence of acute changes in pulse wave velocity and flow-mediated slowing.
Published in Vascular medicine (London, England)
Flow-mediated slowing (FMS), defined as the minimum pulse wave velocity (PWVmin) during reactive hyperemia, is potentially a simple, user-objective test for examining endothelial function. The purpose of the current study was to determine the effects of a known endothelial dysfunction protocol on arm PWV and PWVmin. Complete data were successfully ...
Circulating miR-106b-5p serves as a diagnostic biomarker for asymptomatic carotid artery stenosis and predicts the occur...
Published in Vascular medicine (London, England)
This study aimed to investigate the expression and diagnostic value of miR-106b-5p in asymptomatic carotid artery stenosis (CAS) patients, and further explore its predictive value for the occurrence of cerebral ischemic events (CIE). A total of 58 asymptomatic CAS cases and 61 healthy controls were recruited. Quantitative RT-PCR was applied for the...
Active smoking is associated with higher rates of incomplete wound healing after endovascular treatment of critical limb...
...Published in Vascular medicine (London, England)
The association between active smoking and wound healing in critical limb ischemia (CLI) is unknown. Our objective was to examine in a retrospective cohort study whether active smoking is associated with higher incomplete wound healing rates in patients with CLI undergoing endovascular interventions. Smoking status was assessed at the time of the i...
Skeletal muscle capillary density is related to anaerobic threshold and claudication in peripheral artery disease.
Published in Vascular medicine (London, England)
Peripheral artery disease (PAD) is characterized by impaired blood flow to the lower extremities, causing claudication and exercise intolerance. Exercise intolerance may result from reduced skeletal muscle capillary density and impaired muscle oxygen delivery. This cross-sectional study tested the hypothesis that capillary density is related to cla...
Melatonin attenuates hypertension and oxidative stress in a rat model of L-NAME-induced gestational hypertension.
Published in Vascular medicine (London, England)
Preeclampsia is a life-threatening multiorgan systemic disease with manifestations including gestational hypertension, oxidative stress, and vascular dysfunction. We aimed to evaluate the therapeutic effects of melatonin on an L-NAME (NLG-nitro-l-arginine methyl ester)-induced rat preeclampsia model. During gestation, L-NAME was added to drinking w...
