Li, Huiqing Gao, Qiang
Published in
Turkish Journal of Biochemistry
ObjectivesHuman serum albumin (HSA) can bind and transport many substances to cells to meet various needs of the organism. The binding efficacy of HSA to these substances directly affects their functions. In this paper two Schiff base compounds were synthesized to explore the interaction between HSA and both compounds.MethodsFluorescence spectra an...
Ardicoglu Akisin, Yasemin Ozis, Salih Erpulat Poyraz, Mustafa Baris Kurt, Halil
Published in
Turkish Journal of Biochemistry
Hepokur, Ceylan Misir, Sema Tunç, Tutku Tutar, Ugur Hepokur, Ali Ihsan Çiçek, Mehmet
Published in
Turkish Journal of Biochemistry
ObjectivesIn this study, we aimed to detect the chemical compounds of Thymbra capitata ethanolic extract (TC-EtOH) as well as to evaluated its antimicrobial, antioxidant, cytotoxic activities, and in vivo wound healing effects.MethodsThe chemical composition of TC-EtOH was analyzed by Gas chromatography-mass spectrometry (GC-MS). Antioxidant and an...
Kısa, Üçler Başar, M. Murad Şipal, Timuçin Ceylan, Özlem Doğan
Published in
Turkish Journal of Biochemistry
ObjectiveThe aim of the present study was to investigate serum ghrelin and orexin levels in patients with varicocele and compare these levels with idiopathic infertile male and healthy control cases.MethodsThis study enrolled 24 men with varicocele, 24 males having idiopathic infertility, and 21 fertile men as the control group. Hormonal analyses, ...
Acan, N. Leyla
Published in
Turkish Journal of Biochemistry
Molecular and kinetic characterizations of the enzymes that lead to the identification of the biochemical reactions constitute an important area of biochemistry. In kinetic studies, kinetic constants and reaction mechanisms are investigated. These studies may lead to novel drug design. Correct results require a precise study and sufficient knowledg...
Baskol, Gulden Mazicioglu, Mumtaz M. Özel, Merve
Published in
Turkish Journal of Biochemistry
The current conditions in the progression of the SARS-CoV2 pandemic changed the current scientific paradigm, and we now observe a novel rhythm and way of evaluating the collected information. Previous experiences in epidemics with similar viruses (viz., SARS-CoV1, and MERS-CoV) and collected information about the viral transmission and replication ...
Abd Elrahman, Hanem G. Ramadan, Abeer Saleh, Eman M. Saleh, Alia A. Sabry, Noha A. Mohamed, Mohamed R.
Published in
Turkish Journal of Biochemistry
GirişAlzheimer Hastalığı, düşünme kapasitesindeki azalma ve kişilikteki değişikliklerle ilişkili genetik olarak heterojen bir beyin hastalığıdır. Alzheimer hastalığının ortaya çıkmasıyla çeşitli gen polimorfizmleri ilişkilendirilebilir.AmaçBu çalışma, Mısır popülasyonunun bir örneğinde ABCA7 rs3764650, CLU rs11136000 ve MS4A6A rs610932 genetik vary...
Matías-Pérez, Diana Pérez-Santiago, Alma Dolores Sánchez-Medina, Marco Antonio García-Montalvo, Iván Antonio
Published in
Turkish Journal of Biochemistry
Yeni koronavirüsün (COVID-19) neden olduğu hastalık, alt solunum yolunu etkilemesine ve yaş, komorbiditeler ve zayıflamış bağışıklık sistemi ile ilişkili olmasının yanı sıra ateş ve öksürük ile karakterizedir. Lenfopeniler şiddetli vakalarda ortaya çıkar ve aşırı inflamatuar sitokin üretimi, COVID-19’un patogenezinde hiperinflamatuar yanıtın rolünü...
Bozaci, Ilter Doğan, Ali Nazmi Can Aktar, Merve Mahşer, Alev Yıldırım, Gizem Serel, Ali Tatar, Erhan
Published in
Turkish Journal of Biochemistry
GirişMetabolik asidoz, kronik böbrek hastalığının (KBH) seyri sırasında sık görülen bir bozukluktur. Bu çalışmada, evre 3–5 kronik böbrek hastalarında Baz açığı (BA), anyon gap (AG) ve delta oranlarının hastalık progresyonu, renal replasman tedavi (RRT) ihtiyacı ve mortalite ile ilişkisini incelemeyi amaçladık.MetodToplam 212 evre 3–5 kronik böbrek...
Yilmaz, Can Bulus, Hakan Oguztuzun, Serpil Cihan, Mehmethan Fidan, Ceylan
Published in
Turkish Journal of Biochemistry
ObjectivesObesity has become an important public health problem because of its increasing prevalence and relation with many diseases and mortality. Studies have shown its association with oxidative stress. In this study, the effect of obesity on total amount of thiol and some glutathione S-transferase (GST) isozymes were investigated which could se...
