Theerasuwipakorn, Nonthikorn Prechawat, Somchai Chokesuwattanaskul, Ronpichai Siranart, Noppachai Marsukjai, Apichai Thumtecho, Suthimon Rungpradubvong, Voravut
Published in
Toxicology Reports
• Cannabis has been increasingly decriminalized or legalized for medical and recreational purposes in recent decades. • The association between cannabis and adverse CV events is still controversial. • This meta-analysis found that cannabis use was not significantly associated with acute MI, stroke, and adverse CV events. • The plausible explanation...
Elmadani, Manar Raatikainen, Sami Mattila, Orvokki Alakoski, Tarja Piuhola, Jarkko Åström, Pirjo Tenhunen, Olli Magga, Johanna Kerkelä, Risto
Published in
Toxicology Reports
• Cardiomyocytes are sensitive to dasatinib-induced cell death. • Dasatinib attenuates the phosphorylation of c-Src target ERK in cardiomyocytes. • Knockdown of c-Src in cardiomyocytes induces cardiomyocyte death. • Dasatinib-resistant mutant of c-Src rescues cardiomyocytes from dasatinib toxicity.
Kim, Boyun Kim, Gaeun Jeon, Soyeon Cho, Wan-Seob Jeon, Hyun Pyo Jung, Jewon
Published in
Toxicology Reports
• Zn2+ causes autophagy-mediated cell death rather than apoptosis. • Inhibition of TRPML1 protects from cell death via interfering with autophagic flux. • Controlling TRPML1 may be potentially used to prevent the kidney from ZnO NPs-induced toxicity.
Yoshino, Yuka Fujii, Yuta Chihara, Kazuhiro Nakae, Aya Enmi, Jun-ichiro Yoshioka, Yoshichika Miyawaki, Izuru
Published in
Toxicology Reports
• 1H-MRS can accurately quantify non-diffuse hepatic steatosis in rats. • Blood biochemistry values were not correlated with histopathology values. • Non-diffuse hepatic steatosis was induced by feeding MCDD in Wistar rats.
Ojo, Oluwafemi Adeleke Nwafor-Ezeh, Pearl Ifunanya Rotimi, Damilare Emmanuel Iyobhebhe, Matthew Ogunlakin, Akingbolabo Daniel Ojo, Adebola Busola
Published in
Toxicology Reports
• Increased apoptosis in both the sperm and ovaries gives off negative effects that contribute to the problem of infertility. • Inflammation performs physiological processes such as ovulation, as well as abnormal sperm production and function. • Overproduction of ROS results in an inflammatory injury in the reproductive tract.
Shabani, Mohammad Bayrami, Deniz Moghadam, Amin Ashena Jamali, Zhaleh Salimi, Ahmad
Published in
Toxicology Reports
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Lamb, Thomas Rahman, Irfan
Published in
Toxicology reports
Macrophages treated with the flavoring chemicals found in flavored electronic cigarettes have been shown to induce an inflammatory response, however, limited data are available on the effect of aerosol exposure to these chemicals. We hypothesized that aerosol exposure to flavoring chemicals found in commercially available flavored e-liquids would r...
Friedman, Nathan Seltzer, Justin Harvey, Helen Ly, Binh Schneir, Aaron
Published in
Toxicology reports
Ethanol remains one of the most frequently abused agents by adolescents, exceeding all others except for vaping nicotine, and use is rising. With increased ethanol use comes a greater risk for dependence and potential for alcohol withdrawal syndromes (AWS). Pediatric AWS is extremely rare and poorly characterized in the literature. Pediatric acute ...
Serra, Loïse Bourdon, Guillaume Estienne, Anthony Fréville, Mathias Ramé, Christelle Chevaleyre, Claire Didier, Philippe Chahnamian, Marine Ganier, Patrice Pinault, Florine
...
Published in
Toxicology Reports
• Triazoles decrease steroidogenesis and lactate production in chicken testis explants. • Triazoles reduce sperm motility and increase ROS production in chicken spermatozoa. • Triazoles increase chicken spermatozoa abnormal morphology. • Triazoles enhance AhR and CAR mRNA expressions in chicken testis explants.
Kasozi, Keneth Iceland Otim, Eric Oloya Zirintunda, Gerald Tamale, Andrew Otim, Ochan
Published in
Toxicology Reports
• We demonstrate how relationships and common sources of metals could be identified among samples in a multivariate space. • The study showed that all beef samples contained these metals, the extent of which were in the order: Fe > Zn >> Ni, Cr > Pb > Cu, Co > Cd.
