Morte, Beatriz Gil-Ibañez, Pilar Heuer, Heike Bernal, Juan
Published in
Thyroid : official journal of the American Thyroid Association
The monocarboxylate transporter 8 (Mct8) protein is a primary T4 and T3 (TH) transporter. Mutations of the MCT8-encoding, SLC16A2 gene alters thyroid function and thyroid hormone metabolism and severely impairs neurodevelopment (Allan-Herndon-Dudley syndrome, AHDS). Mct8-deficient mice manifest thyroid alterations but lack neurological signs. It is...
Corrado, Alda Aceto, Romina Silvestri, Roberto Dell'Anno, Irene Ricci, Benedetta Miglietta, Simona Romei, Cristina Giovannoni, Roberto Poliseno, Laura Evangelista, Monica
...
Published in
Thyroid : official journal of the American Thyroid Association
Galectin-3 (LGALS3) is an important glycoprotein involved in the malignant transformation of thyrocytes acting in the extracellular matrix, cytoplasm and nucleus where it regulates TTF-1 and TCF4 transcription factors. Within LGALS3 gene, a common genetic polymorphism (c.191C>A, p.Pro64His; rs4644) encoding for the variant Proline to Histidine at c...
Furman, Ary E Dumitrescu, Alexandra M Refetoff, Samuel Weiss, Roy E
Published in
Thyroid : official journal of the American Thyroid Association
Resistance to thyroid hormone alpha (RTHα) is caused by mutations in thyroid hormone receptor α (THRA). Little is known about the natural history and treatment of RTHα, and diagnosis before the age of 1 year has not been previously reported. A de novo heterozygous THRA mutation (pC380SfsX9) was identified in a 10-month-old female investigated for d...
Chung, Sae Rom Choi, Young Jun Lee, Seung Soo Kim, Seon-Ok Lee, Sun-Ah Jeon, Min Ji Kim, Won Gu Lee, Jeong Hyun Baek, Jung Hwan
Published in
Thyroid : official journal of the American Thyroid Association
Active surveillance is recommended as an alternative to immediate surgery for low-risk papillary thyroid microcarcinoma (PTMC), and determining meaningful changes in diameter and volume on ultrasonography (US) is critical. However, interobserver reproducibility of the sonographic measurement of maximum diameter and volume of PTMC has not been well ...
Lee, Young Ah Yun, Hyo Ri Lee, Juneyoung Moon, Hyemi Shin, Choong Ho Kim, Sin Gon Park, Young Joo
Published in
Thyroid : official journal of the American Thyroid Association
Background: The incidence of thyroid cancer has increased worldwide. We investigated nationwide trends in the incidence and treatment course of pediatric thyroid cancer in South Korea. Methods: Using the National Health Information Database, we analyzed 1580 patients (324 males)
Silva de Morais, Nathalie Ayres Saraiva, Débora Corcino, Carolina Berbara, Tatiana Schtscherbyna, Annie Moreira, Karina Vaisman, Mario Alexander, Erik K Teixeira, Patrícia
Published in
Thyroid : official journal of the American Thyroid Association
Background: Insufficient or excessive iodine intake during gestation may compromise adaptive mechanisms in maternal thyroid function and lead to adverse pregnancy outcomes. In this context, we aimed to study the effects of maternal iodine status in the first and third trimesters of gestation on obstetric and neonatal outcomes in an iodine-sufficien...
Bernardi, Stella Giudici, Fabiola Cesareo, Roberto Antonelli, Giovanni Cavallaro, Marco Deandrea, Maurilio Giusti, Massimo Mormile, Alberto Negro, Roberto Palermo, Andrea
...
Published in
Thyroid : official journal of the American Thyroid Association
Background: Radiofrequency ablation (RFA) and laser ablation (LA) are effective treatments for benign thyroid nodules. Due to their relatively recent introduction into clinical practice, there are limited long-term follow-up studies. This study aimed to evaluate technique efficacy, rate of regrowth, and retreatment over 5 years after RFA or LA and ...
Fitzgerald, Stephen P Bean, Nigel G Falhammar, Henrik Tuke, Jono
Published in
Thyroid : official journal of the American Thyroid Association
Background: Though the functional states of other endocrine systems are not defined on the basis of levels of controlling hormones, the assessment of thyroid function is based on levels of the controlling hormone thyrotropin (TSH). We, therefore, addressed the question as to whether levels of thyroid hormones [free thyroxine (fT4), total triiodothy...
Fitzgerald, Stephen P Bean, Nigel G Falhammar, Henrik
Published in
Thyroid : official journal of the American Thyroid Association
Pekova, Barbora Sykorova, Vlasta Dvorakova, Sarka Vaclavikova, Eliska Moravcova, Jitka Katra, Rami Astl, Jaromir Vlcek, Petr Kodetova, Daniela Vcelak, Josef
...
Published in
Thyroid : official journal of the American Thyroid Association
Background: Pediatric papillary thyroid carcinoma (PTC) is a rare malignancy, but with increasing incidence. Pediatric PTCs have distinct clinical and pathological features and even the molecular profile differs from adult PTCs. Somatic point mutations in pediatric PTCs have been previously described and studied, but complex information about fusio...
